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Items: 1 to 20 of 31


Transforming growth factor-β enhances Rho-kinase activity and contraction in airway smooth muscle via the nucleotide exchange factor ARHGEF1.

Shaifta Y, MacKay CE, Irechukwu N, O'Brien KA, Wright DB, Ward JPT, Knock GA.

J Physiol. 2018 Jan 1;596(1):47-66. doi: 10.1113/JP275033. Epub 2017 Nov 23.


The Biology of Eosinophils and Their Role in Asthma.

McBrien CN, Menzies-Gow A.

Front Med (Lausanne). 2017 Jun 30;4:93. doi: 10.3389/fmed.2017.00093. eCollection 2017. Review.


Transforming Growth Factor β1 Function in Airway Remodeling and Hyperresponsiveness. The Missing Link?

Ojiaku CA, Yoo EJ, Panettieri RA Jr.

Am J Respir Cell Mol Biol. 2017 Apr;56(4):432-442. doi: 10.1165/rcmb.2016-0307TR. Review.


Emerging concepts in smooth muscle contributions to airway structure and function: implications for health and disease.

Prakash YS.

Am J Physiol Lung Cell Mol Physiol. 2016 Dec 1;311(6):L1113-L1140. doi: 10.1152/ajplung.00370.2016. Epub 2016 Oct 14. Review.


Airway smooth muscle in airway reactivity and remodeling: what have we learned?

Prakash YS.

Am J Physiol Lung Cell Mol Physiol. 2013 Dec;305(12):L912-33. doi: 10.1152/ajplung.00259.2013. Epub 2013 Oct 18. Review.


Bronchoconstriction Induces TGF-β Release and Airway Remodelling in Guinea Pig Lung Slices.

Oenema TA, Maarsingh H, Smit M, Groothuis GM, Meurs H, Gosens R.

PLoS One. 2013 Jun 26;8(6):e65580. doi: 10.1371/journal.pone.0065580. Print 2013.


Transforming growth factor-β-induced differentiation of airway smooth muscle cells is inhibited by fibroblast growth factor-2.

Schuliga M, Javeed A, Harris T, Xia Y, Qin C, Wang Z, Zhang X, Lee PV, Camoretti-Mercado B, Stewart AG.

Am J Respir Cell Mol Biol. 2013 Mar;48(3):346-53. doi: 10.1165/rcmb.2012-0151OC. Epub 2012 Dec 13.


PCR based bronchoscopic detection of common respiratory pathogens in chronic cough: a case control study.

West PW, Kelsall A, Decalmer S, Dove W, Bishop PW, Stewart JP, Woodcock AA, Smith JA.

Cough. 2012 Sep 14;8(1):5. doi: 10.1186/1745-9974-8-5.


The pivotal role of airway smooth muscle in asthma pathophysiology.

Ozier A, Allard B, Bara I, Girodet PO, Trian T, Marthan R, Berger P.

J Allergy (Cairo). 2011;2011:742710. doi: 10.1155/2011/742710. Epub 2011 Dec 11.


Transforming growth factor-β and nuclear factor E2–related factor 2 regulate antioxidant responses in airway smooth muscle cells: role in asthma.

Michaeloudes C, Chang PJ, Petrou M, Chung KF.

Am J Respir Crit Care Med. 2011 Oct 15;184(8):894-903. doi: 10.1164/rccm.201011-1780OC.


Reconstruction is not renovation - the role of remodeling in asthma.

Weckmann M, Trian T, Oliver BG.

J Asthma Allergy. 2009 Mar 16;2:33-42.


Akt activation induces hypertrophy without contractile phenotypic maturation in airway smooth muscle.

Ma L, Brown M, Kogut P, Serban K, Li X, McConville J, Chen B, Bentley JK, Hershenson MB, Dulin N, Solway J, Camoretti-Mercado B.

Am J Physiol Lung Cell Mol Physiol. 2011 May;300(5):L701-9. doi: 10.1152/ajplung.00119.2009. Epub 2011 Mar 4.


Hydrogen sulfide inhibits proliferation and release of IL-8 from human airway smooth muscle cells.

Perry MM, Hui CK, Whiteman M, Wood ME, Adcock I, Kirkham P, Michaeloudes C, Chung KF.

Am J Respir Cell Mol Biol. 2011 Oct;45(4):746-52. doi: 10.1165/rcmb.2010-0304OC. Epub 2011 Feb 4.


Caveolin-1 is required for contractile phenotype expression by airway smooth muscle cells.

Gosens R, Stelmack GL, Bos ST, Dueck G, Mutawe MM, Schaafsma D, Unruh H, Gerthoffer WT, Zaagsma J, Meurs H, Halayko AJ.

J Cell Mol Med. 2011 Nov;15(11):2430-42. doi: 10.1111/j.1582-4934.2010.01246.x.


TGF-β regulates Nox4, MnSOD and catalase expression, and IL-6 release in airway smooth muscle cells.

Michaeloudes C, Sukkar MB, Khorasani NM, Bhavsar PK, Chung KF.

Am J Physiol Lung Cell Mol Physiol. 2011 Feb;300(2):L295-304. doi: 10.1152/ajplung.00134.2010. Epub 2010 Dec 3.


Stretch augments TGF-beta1 expression through RhoA/ROCK1/2, PTK, and PI3K in airway smooth muscle cells.

Mohamed JS, Boriek AM.

Am J Physiol Lung Cell Mol Physiol. 2010 Sep;299(3):L413-24. doi: 10.1152/ajplung.90628.2008. Epub 2010 May 28.


Interferons modulate mitogen-induced protein synthesis in airway smooth muscle.

Goncharova EA, Lim PN, Chisolm A, Fogle HW 3rd, Taylor JH, Goncharov DA, Eszterhas A, Panettieri RA Jr, Krymskaya VP.

Am J Physiol Lung Cell Mol Physiol. 2010 Jul;299(1):L25-35. doi: 10.1152/ajplung.00228.2009. Epub 2010 Apr 9.


Pulmonary artery smooth muscle hypertrophy: roles of glycogen synthase kinase-3beta and p70 ribosomal S6 kinase.

Deng H, Hershenson MB, Lei J, Anyanwu AC, Pinsky DJ, Bentley JK.

Am J Physiol Lung Cell Mol Physiol. 2010 Jun;298(6):L793-803. doi: 10.1152/ajplung.00108.2009. Epub 2010 Feb 26.


Chronic inflammation and asthma.

Murdoch JR, Lloyd CM.

Mutat Res. 2010 Aug 7;690(1-2):24-39. doi: 10.1016/j.mrfmmm.2009.09.005. Epub 2009 Sep 19. Review.


p70 Ribosomal S6 kinase is required for airway smooth muscle cell size enlargement but not increased contractile protein expression.

Deng H, Hershenson MB, Lei J, Bitar KN, Fingar DC, Solway J, Bentley JK.

Am J Respir Cell Mol Biol. 2010 Jun;42(6):744-52. doi: 10.1165/rcmb.2009-0037OC. Epub 2009 Jul 31.

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