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Items: 15

1.

Human CTP synthase filament structure reveals the active enzyme conformation.

Lynch EM, Hicks DR, Shepherd M, Endrizzi JA, Maker A, Hansen JM, Barry RM, Gitai Z, Baldwin EP, Kollman JM.

Nat Struct Mol Biol. 2017 Jun;24(6):507-514. doi: 10.1038/nsmb.3407. Epub 2017 May 1.

PMID:
28459447
2.

Critical roles of CTP synthase N-terminal in cytoophidium assembly.

Huang Y, Wang JJ, Ghosh S, Liu JL.

Exp Cell Res. 2017 May 15;354(2):122-133. doi: 10.1016/j.yexcr.2017.03.042. Epub 2017 Mar 22.

3.

Inhibition of Escherichia coli CTP Synthetase by NADH and Other Nicotinamides and Their Mutual Interactions with CTP and GTP.

Habrian C, Chandrasekhara A, Shahrvini B, Hua B, Lee J, Jesinghaus R, Barry R, Gitai Z, Kollman J, Baldwin EP.

Biochemistry. 2016 Oct 4;55(39):5554-5565. Epub 2016 Sep 19.

4.

Thiophenecarboxamide Derivatives Activated by EthA Kill Mycobacterium tuberculosis by Inhibiting the CTP Synthetase PyrG.

Mori G, Chiarelli LR, Esposito M, Makarov V, Bellinzoni M, Hartkoorn RC, Degiacomi G, Boldrin F, Ekins S, de Jesus Lopes Ribeiro AL, Marino LB, Centárová I, Svetlíková Z, Blaško J, Kazakova E, Lepioshkin A, Barilone N, Zanoni G, Porta A, Fondi M, Fani R, Baulard AR, Mikušová K, Alzari PM, Manganelli R, de Carvalho LP, Riccardi G, Cole ST, Pasca MR.

Chem Biol. 2015 Jul 23;22(7):917-27. doi: 10.1016/j.chembiol.2015.05.016. Epub 2015 Jun 18.

5.

Nucleotide synthesis is regulated by cytoophidium formation during neurodevelopment and adaptive metabolism.

Aughey GN, Grice SJ, Shen QJ, Xu Y, Chang CC, Azzam G, Wang PY, Freeman-Mills L, Pai LM, Sung LY, Yan J, Liu JL.

Biol Open. 2014 Oct 17;3(11):1045-56. doi: 10.1242/bio.201410165.

6.

Large-scale filament formation inhibits the activity of CTP synthetase.

Barry RM, Bitbol AF, Lorestani A, Charles EJ, Habrian CH, Hansen JM, Li HJ, Baldwin EP, Wingreen NS, Kollman JM, Gitai Z.

Elife. 2014 Jul 16;3:e03638. doi: 10.7554/eLife.03638.

7.

Common regulatory control of CTP synthase enzyme activity and filament formation.

Noree C, Monfort E, Shiau AK, Wilhelm JE.

Mol Biol Cell. 2014 Aug 1;25(15):2282-90. doi: 10.1091/mbc.E14-04-0912. Epub 2014 Jun 11.

8.

Gates of enzymes.

Gora A, Brezovsky J, Damborsky J.

Chem Rev. 2013 Aug 14;113(8):5871-923. doi: 10.1021/cr300384w. Epub 2013 Apr 25. Review. No abstract available.

9.

Only one isoform of Drosophila melanogaster CTP synthase forms the cytoophidium.

Azzam G, Liu JL.

PLoS Genet. 2013;9(2):e1003256. doi: 10.1371/journal.pgen.1003256. Epub 2013 Feb 14.

10.

Structure of the dimeric form of CTP synthase from Sulfolobus solfataricus.

Lauritsen I, Willemoës M, Jensen KF, Johansson E, Harris P.

Acta Crystallogr Sect F Struct Biol Cryst Commun. 2011 Feb 1;67(Pt 2):201-8. doi: 10.1107/S1744309110052334. Epub 2011 Jan 21.

11.

Regulation of human cytidine triphosphate synthetase 2 by phosphorylation.

Kassel KM, Au da R, Higgins MJ, Hines M, Graves LM.

J Biol Chem. 2010 Oct 29;285(44):33727-36. doi: 10.1074/jbc.M110.178566. Epub 2010 Aug 25.

12.

Identification of novel filament-forming proteins in Saccharomyces cerevisiae and Drosophila melanogaster.

Noree C, Sato BK, Broyer RM, Wilhelm JE.

J Cell Biol. 2010 Aug 23;190(4):541-51. doi: 10.1083/jcb.201003001. Epub 2010 Aug 16.

13.

CTP synthetase and its role in phospholipid synthesis in the yeast Saccharomyces cerevisiae.

Chang YF, Carman GM.

Prog Lipid Res. 2008 Sep;47(5):333-9. doi: 10.1016/j.plipres.2008.03.004. Epub 2008 Apr 7. Review.

14.

Phosphorylation of human CTP synthetase 1 by protein kinase C: identification of Ser(462) and Thr(455) as major sites of phosphorylation.

Chang YF, Martin SS, Baldwin EP, Carman GM.

J Biol Chem. 2007 Jun 15;282(24):17613-22. Epub 2007 Apr 26.

15.

Structure of the synthetase domain of human CTP synthetase, a target for anticancer therapy.

Kursula P, Flodin S, Ehn M, Hammarström M, Schüler H, Nordlund P, Stenmark P.

Acta Crystallogr Sect F Struct Biol Cryst Commun. 2006 Jul 1;62(Pt 7):613-7. Epub 2006 Jun 10.

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