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Recombinant Adenoviruses Displaying Matrix 2 Ectodomain Epitopes on Their Fiber Proteins as Universal Influenza Vaccines.

Tang X, Yang Y, Xia X, Zhang C, Yang X, Song Y, Dai X, Wang M, Zhou D.

J Virol. 2017 Mar 13;91(7). pii: e02462-16. doi: 10.1128/JVI.02462-16. Print 2017 Apr 1.


Recent advancements in combination subunit vaccine development.

Tan M, Jiang X.

Hum Vaccin Immunother. 2017 Jan 2;13(1):180-185. doi: 10.1080/21645515.2016.1229719.


Mechanisms of Cross-protection by Influenza Virus M2-based Vaccines.

Lee YN, Kim MC, Lee YT, Kim YJ, Kang SM.

Immune Netw. 2015 Oct;15(5):213-21. doi: 10.4110/in.2015.15.5.213. Epub 2015 Oct 26. Review.


Cross Protection against Influenza A Virus by Yeast-Expressed Heterologous Tandem Repeat M2 Extracellular Proteins.

Lee YN, Kim MC, Lee YT, Hwang HS, Lee J, Kim C, Kang SM.

PLoS One. 2015 Sep 14;10(9):e0137822. doi: 10.1371/journal.pone.0137822. eCollection 2015.


M2e-Based Universal Influenza A Vaccines.

Deng L, Cho KJ, Fiers W, Saelens X.

Vaccines (Basel). 2015 Feb 13;3(1):105-36. doi: 10.3390/vaccines3010105. Review.


Potential recombinant vaccine against influenza A virus based on M2e displayed on nodaviral capsid nanoparticles.

Yong CY, Yeap SK, Ho KL, Omar AR, Tan WS.

Int J Nanomedicine. 2015 Apr 2;10:2751-63. doi: 10.2147/IJN.S77405. eCollection 2015.


Mucosal vaccination with recombinant Lactobacillus casei-displayed CTA1-conjugated consensus matrix protein-2 (sM2) induces broad protection against divergent influenza subtypes in BALB/c mice.

Chowdhury MY, Li R, Kim JH, Park ME, Kim TH, Pathinayake P, Weeratunga P, Song MK, Son HY, Hong SP, Sung MH, Lee JS, Kim CJ.

PLoS One. 2014 Apr 8;9(4):e94051. doi: 10.1371/journal.pone.0094051. eCollection 2014.


Subviral particle as vaccine and vaccine platform.

Tan M, Jiang X.

Curr Opin Virol. 2014 Jun;6:24-33. doi: 10.1016/j.coviro.2014.02.009. Epub 2014 Mar 21. Review.


Intranasal immunization with influenza antigens conjugated with cholera toxin subunit B stimulates broad spectrum immunity against influenza viruses.

Li J, Arévalo MT, Chen Y, Posadas O, Smith JA, Zeng M.

Hum Vaccin Immunother. 2014;10(5):1211-20. doi: 10.4161/hv.28407. Epub 2014 Mar 14.


New vaccines against influenza virus.

Lee YT, Kim KH, Ko EJ, Lee YN, Kim MC, Kwon YM, Tang Y, Cho MK, Lee YJ, Kang SM.

Clin Exp Vaccine Res. 2014 Jan;3(1):12-28. doi: 10.7774/cevr.2014.3.1.12. Epub 2013 Dec 18. Review.


Nanoclusters self-assembled from conformation-stabilized influenza M2e as broadly cross-protective influenza vaccines.

Wang L, Hess A, Chang TZ, Wang YC, Champion JA, Compans RW, Wang BZ.

Nanomedicine. 2014 Feb;10(2):473-82. doi: 10.1016/j.nano.2013.08.005. Epub 2013 Aug 27.


Virus-like particles containing the tetrameric ectodomain of influenza matrix protein 2 and flagellin induce heterosubtypic protection in mice.

Wang L, Wang YC, Feng H, Ahmed T, Compans RW, Wang BZ.

Biomed Res Int. 2013;2013:686549. doi: 10.1155/2013/686549. Epub 2013 Jul 30.


Gold nanoparticle-M2e conjugate coformulated with CpG induces protective immunity against influenza A virus.

Tao W, Ziemer KS, Gill HS.

Nanomedicine (Lond). 2014 Feb;9(2):237-51. doi: 10.2217/nnm.13.58. Epub 2013 Jul 5.


Multiple heterologous M2 extracellular domains presented on virus-like particles confer broader and stronger M2 immunity than live influenza A virus infection.

Kim MC, Lee JS, Kwon YM, O E, Lee YJ, Choi JG, Wang BZ, Compans RW, Kang SM.

Antiviral Res. 2013 Sep;99(3):328-35. doi: 10.1016/j.antiviral.2013.06.010. Epub 2013 Jun 27.


The prospects and challenges of universal vaccines for influenza.

Subbarao K, Matsuoka Y.

Trends Microbiol. 2013 Jul;21(7):350-8. doi: 10.1016/j.tim.2013.04.003. Epub 2013 May 17. Review.


Immunization with a MOMP-based vaccine protects mice against a pulmonary Chlamydia challenge and identifies a disconnection between infection and pathology.

O'Meara CP, Armitage CW, Harvie MC, Timms P, Lycke NY, Beagley KW.

PLoS One. 2013 Apr 16;8(4):e61962. doi: 10.1371/journal.pone.0061962. Print 2013.


Robust immunity and heterologous protection against influenza in mice elicited by a novel recombinant NP-M2e fusion protein expressed in E. coli.

Wang W, Huang B, Jiang T, Wang X, Qi X, Gao Y, Tan W, Ruan L.

PLoS One. 2012;7(12):e52488. doi: 10.1371/journal.pone.0052488. Epub 2012 Dec 21.


Virus-like particles containing multiple M2 extracellular domains confer improved cross-protection against various subtypes of influenza virus.

Kim MC, Song JM, O E, Kwon YM, Lee YJ, Compans RW, Kang SM.

Mol Ther. 2013 Feb;21(2):485-92. doi: 10.1038/mt.2012.246. Epub 2012 Dec 18.

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