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Items: 17


Cancer of the Peripheral Nerve in Neurofibromatosis Type 1.

Staedtke V, Bai RY, Blakeley JO.

Neurotherapeutics. 2017 Apr;14(2):298-306. doi: 10.1007/s13311-017-0518-y. Review.


Branched Gold Nanoparticle Coating of Clostridium novyi-NT Spores for CT-Guided Intratumoral Injection.

Park W, Cho S, Huang X, Larson AC, Kim DH.

Small. 2017 Feb;13(5). doi: 10.1002/smll.201602722. Epub 2016 Nov 15.


Three-dimensional tumor spheroids for in vitro analysis of bacteria as gene delivery vectors in tumor therapy.

Osswald A, Sun Z, Grimm V, Ampem G, Riegel K, Westendorf AM, Sommergruber W, Otte K, Dürre P, Riedel CU.

Microb Cell Fact. 2015 Dec 12;14:199. doi: 10.1186/s12934-015-0383-5.


Combining anaerobic bacterial oncolysis with vaccination that blocks interleukin-10 signaling may achieve better outcomes for late stage cancer management.

Ni G, Wang T, Yang L, Wang Y, Liu X, Wei MQ.

Hum Vaccin Immunother. 2016 Mar 3;12(3):599-606. doi: 10.1080/21645515.2015.1089008.


Clostridium novyi-NT can cause regression of orthotopically implanted glioblastomas in rats.

Staedtke V, Bai RY, Sun W, Huang J, Kibler KK, Tyler BM, Gallia GL, Kinzler K, Vogelstein B, Zhou S, Riggins GJ.

Oncotarget. 2015 Mar 20;6(8):5536-46.


Intratumoral injection of Clostridium novyi-NT spores induces antitumor responses.

Roberts NJ, Zhang L, Janku F, Collins A, Bai RY, Staedtke V, Rusk AW, Tung D, Miller M, Roix J, Khanna KV, Murthy R, Benjamin RS, Helgason T, Szvalb AD, Bird JE, Roy-Chowdhuri S, Zhang HH, Qiao Y, Karim B, McDaniel J, Elpiner A, Sahora A, Lachowicz J, Phillips B, Turner A, Klein MK, Post G, Diaz LA Jr, Riggins GJ, Papadopoulos N, Kinzler KW, Vogelstein B, Bettegowda C, Huso DL, Varterasian M, Saha S, Zhou S.

Sci Transl Med. 2014 Aug 13;6(249):249ra111. doi: 10.1126/scitranslmed.3008982.


Spores of Clostridium engineered for clinical efficacy and safety cause regression and cure of tumors in vivo.

Heap JT, Theys J, Ehsaan M, Kubiak AM, Dubois L, Paesmans K, Mellaert LV, Knox R, Kuehne SA, Lambin P, Minton NP.

Oncotarget. 2014 Apr 15;5(7):1761-9.


Escherichia coli Nissle 1917 targets and restrains mouse B16 melanoma and 4T1 breast tumors through expression of azurin protein.

Zhang Y, Zhang Y, Xia L, Zhang X, Ding X, Yan F, Wu F.

Appl Environ Microbiol. 2012 Nov;78(21):7603-10. doi: 10.1128/AEM.01390-12. Epub 2012 Aug 24.


Evaluation of Clostridium novyi-NT spores in dogs with naturally occurring tumors.

Krick EL, Sorenmo KU, Rankin SC, Cheong I, Kobrin B, Thornton K, Kinzler KW, Vogelstein B, Zhou S, Diaz LA Jr.

Am J Vet Res. 2012 Jan;73(1):112-8. doi: 10.2460/ajvr.73.1.112.


Bacterial immunotherapy of gastrointestinal tumors.

Linnebacher M, Maletzki C, Klier U, Klar E.

Langenbecks Arch Surg. 2012 Apr;397(4):557-68. doi: 10.1007/s00423-011-0892-6. Epub 2011 Dec 22. Review.


Structural characterization of the polar lipids of Clostridium novyi NT. Further evidence for a novel anaerobic biosynthetic pathway to plasmalogens.

Guan Z, Johnston NC, Aygun-Sunar S, Daldal F, Raetz CR, Goldfine H.

Biochim Biophys Acta. 2011 Mar;1811(3):186-93. doi: 10.1016/j.bbalip.2010.12.010. Epub 2010 Dec 30.


Bacteriolytic therapy of experimental pancreatic carcinoma.

Maletzki C, Gock M, Klier U, Klar E, Linnebacher M.

World J Gastroenterol. 2010 Jul 28;16(28):3546-52.


Bacteria in cancer therapy: a novel experimental strategy.

Patyar S, Joshi R, Byrav DS, Prakash A, Medhi B, Das BK.

J Biomed Sci. 2010 Mar 23;17(1):21. doi: 10.1186/1423-0127-17-21. Review.


Imaging virus-associated cancer.

Fu DX, Foss CA, Nimmagadda S, Ambinder RF, Pomper MG.

Curr Pharm Des. 2008;14(28):3048-65. Review.


Optimized clostridium-directed enzyme prodrug therapy improves the antitumor activity of the novel DNA cross-linking agent PR-104.

Liu SC, Ahn GO, Kioi M, Dorie MJ, Patterson AV, Brown JM.

Cancer Res. 2008 Oct 1;68(19):7995-8003. doi: 10.1158/0008-5472.CAN-08-1698.


Imaging of musculoskeletal bacterial infections by [124I]FIAU-PET/CT.

Diaz LA Jr, Foss CA, Thornton K, Nimmagadda S, Endres CJ, Uzuner O, Seyler TM, Ulrich SD, Conway J, Bettegowda C, Agrawal N, Cheong I, Zhang X, Ladenson PW, Vogelstein BN, Mont MA, Zhou S, Kinzler KW, Vogelstein B, Pomper MG.

PLoS One. 2007 Oct 10;2(10):e1007.


Spore coat architecture of Clostridium novyi NT spores.

Plomp M, McCaffery JM, Cheong I, Huang X, Bettegowda C, Kinzler KW, Zhou S, Vogelstein B, Malkin AJ.

J Bacteriol. 2007 Sep;189(17):6457-68. Epub 2007 Jun 22.

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