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Ibuprofen results in alterations of human fetal testis development.

Ben Maamar M, Lesné L, Hennig K, Desdoits-Lethimonier C, Kilcoyne KR, Coiffec I, Rolland AD, Chevrier C, Kristensen DM, Lavoué V, Antignac JP, Le Bizec B, Dejucq-Rainsford N, Mitchell RT, Mazaud-Guittot S, Jégou B.

Sci Rep. 2017 Mar 10;7:44184. doi: 10.1038/srep44184.


A risk assessment of a common drug using xenograft model.

Kodama M, Kurokawa J.

Ann Transl Med. 2017 Feb;5(4):88. doi: 10.21037/atm.2017.01.59. No abstract available.


Acetylsalicylic acid interferes with embryonic kidney growth and development by a prostaglandin-independent mechanism.

Welham SJ, Sparrow AJ, Gardner DS, Elmes MJ.

World J Nephrol. 2017 Jan 6;6(1):21-28. doi: 10.5527/wjn.v6.i1.21.


Association of Prenatal Ibuprofen Exposure with Birth Weight and Gestational Age: A Population-Based Sibling Study.

Nezvalová-Henriksen K, Wood M, Spigset O, Nordeng H.

PLoS One. 2016 Dec 9;11(12):e0166971. doi: 10.1371/journal.pone.0166971.


Preconception use of pain-relievers and time-to-pregnancy: a prospective cohort study.

McInerney KA, Hatch EE, Wesselink AK, Rothman KJ, Mikkelsen EM, Wise LA.

Hum Reprod. 2017 Jan;32(1):103-111.


Pregnancy-Associated Changes in Pharmacokinetics: A Systematic Review.

Pariente G, Leibson T, Carls A, Adams-Webber T, Ito S, Koren G.

PLoS Med. 2016 Nov 1;13(11):e1002160. doi: 10.1371/journal.pmed.1002160.


Prenatal paracetamol exposure is associated with shorter anogenital distance in male infants.

Fisher BG, Thankamony A, Hughes IA, Ong KK, Dunger DB, Acerini CL.

Hum Reprod. 2016 Nov;31(11):2642-2650. Epub 2016 Sep 8.


Association of Acetaminophen Use During Pregnancy With Behavioral Problems in Childhood: Evidence Against Confounding.

Stergiakouli E, Thapar A, Davey Smith G.

JAMA Pediatr. 2016 Oct 1;170(10):964-970. doi: 10.1001/jamapediatrics.2016.1775.


Placental control of drug delivery.

Al-Enazy S, Ali S, Albekairi N, El-Tawil M, Rytting E.

Adv Drug Deliv Rev. 2016 Aug 12. pii: S0169-409X(16)30234-4. doi: 10.1016/j.addr.2016.08.002. [Epub ahead of print] Review.


Urinary paracetamol and time-to-pregnancy.

Smarr MM, Grantz KL, Sundaram R, Maisog JM, Honda M, Kannan K, Buck Louis GM.

Hum Reprod. 2016 Sep;31(9):2119-27. doi: 10.1093/humrep/dew172.


Is There a Causal Relation between Maternal Acetaminophen Administration and ADHD?

Saad A, Hegde S, Kechichian T, Gamble P, Rahman M, Stutz SJ, Anastasio NC, Alshehri W, Lei J, Mori S, Kajs B, Cunningham KA, Saade G, Burd I, Costantine M.

PLoS One. 2016 Jun 13;11(6):e0157380. doi: 10.1371/journal.pone.0157380.


Direct-to-Patient Research: Piloting a New Approach to Understanding Drug Safety During Pregnancy.

Dreyer NA, Blackburn SC, Mt-Isa S, Richardson JL, Thomas S, Laursen M, Zetstra-van der Woude P, Jamry-Dziurla A, Hliva V, Bourke A, de Jong-van den Berg L.

JMIR Public Health Surveill. 2015 Dec 22;1(2):e22. doi: 10.2196/publichealth.4939.


Analgesic exposure in pregnant rats affects fetal germ cell development with inter-generational reproductive consequences.

Dean A, van den Driesche S, Wang Y, McKinnell C, Macpherson S, Eddie SL, Kinnell H, Hurtado-Gonzalez P, Chambers TJ, Stevenson K, Wolfinger E, Hrabalkova L, Calarrao A, Bayne RA, Hagen CP, Mitchell RT, Anderson RA, Sharpe RM.

Sci Rep. 2016 Jan 27;6:19789. doi: 10.1038/srep19789.


Medication use during pregnancy, gestational age and date of delivery: agreement between maternal self-reports and health database information in a cohort.

Pisa FE, Casetta A, Clagnan E, Michelesio E, Vecchi Brumatti L, Barbone F.

BMC Pregnancy Childbirth. 2015 Nov 25;15:310. doi: 10.1186/s12884-015-0745-3.


A case-control study of sporadic retinoblastoma in relation to maternal health conditions and reproductive factors: a report from the Children's Oncology group.

Heck JE, Omidakhsh N, Azary S, Ritz B, von Ehrenstein OS, Bunin GR, Ganguly A.

BMC Cancer. 2015 Oct 19;15:735. doi: 10.1186/s12885-015-1773-0.


Do the Levels of Maternal Plasma Trace Elements Affect Fetal Nuchal Translucency Thickness?

Liao KW, Tsai MS, Chang CH, Chien LC, Mao IF, Tsai YA, Chen ML.

PLoS One. 2015 Sep 14;10(9):e0138145. doi: 10.1371/journal.pone.0138145.


Prolonged exposure to acetaminophen reduces testosterone production by the human fetal testis in a xenograft model.

van den Driesche S, Macdonald J, Anderson RA, Johnston ZC, Chetty T, Smith LB, McKinnell C, Dean A, Homer NZ, Jorgensen A, Camacho-Moll ME, Sharpe RM, Mitchell RT.

Sci Transl Med. 2015 May 20;7(288):288ra80. doi: 10.1126/scitranslmed.aaa4097.


NSAIDs and spontaneous abortions - true effect or an indication bias?

Daniel S, Koren G, Lunenfeld E, Levy A.

Br J Clin Pharmacol. 2015 Oct;80(4):750-4. doi: 10.1111/bcp.12653.


Next steps for birth defects research and prevention: The birth defects study to evaluate pregnancy exposures (BD-STEPS).

Tinker SC, Carmichael SL, Anderka M, Browne ML, Caspers Conway KM, Meyer RE, Nembhard WN, Olney RS, Reefhuis J; Birth Defects Study To Evaluate Pregnancy exposureS..

Birth Defects Res A Clin Mol Teratol. 2015 Aug;103(8):733-40. doi: 10.1002/bdra.23373.


Antihistamines and birth defects: a systematic review of the literature.

Gilboa SM, Ailes EC, Rai RP, Anderson JA, Honein MA.

Expert Opin Drug Saf. 2014 Dec;13(12):1667-98. doi: 10.1517/14740338.2014.970164. Review.

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