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Items: 1 to 20 of 26

2.

Phosphorylation regulates the ubiquitin-independent degradation of yeast Pah1 phosphatidate phosphatase by the 20S proteasome.

Hsieh LS, Su WM, Han GS, Carman GM.

J Biol Chem. 2015 May 1;290(18):11467-78. doi: 10.1074/jbc.M115.648659. Epub 2015 Mar 25.

3.

Sestrin 2 protein regulates platelet-derived growth factor receptor β (Pdgfrβ) expression by modulating proteasomal and Nrf2 transcription factor functions.

Tomasovic A, Kurrle N, Sürün D, Heidler J, Husnjak K, Poser I, Schnütgen F, Scheibe S, Seimetz M, Jaksch P, Hyman A, Weissmann N, von Melchner H.

J Biol Chem. 2015 Apr 10;290(15):9738-52. doi: 10.1074/jbc.M114.632133. Epub 2015 Feb 25.

4.

The circadian factor Period 2 modulates p53 stability and transcriptional activity in unstressed cells.

Gotoh T, Vila-Caballer M, Santos CS, Liu J, Yang J, Finkielstein CV.

Mol Biol Cell. 2014 Oct 1;25(19):3081-93. doi: 10.1091/mbc.E14-05-0993. Epub 2014 Aug 7.

5.

Understanding the mechanism of proteasome 20S core particle gating.

Latham MP, Sekhar A, Kay LE.

Proc Natl Acad Sci U S A. 2014 Apr 15;111(15):5532-7. doi: 10.1073/pnas.1322079111. Epub 2014 Mar 31.

6.

Emodin and Aloe-Emodin Suppress Breast Cancer Cell Proliferation through ER α Inhibition.

Huang PH, Huang CY, Chen MC, Lee YT, Yue CH, Wang HY, Lin H.

Evid Based Complement Alternat Med. 2013;2013:376123. doi: 10.1155/2013/376123. Epub 2013 Jun 24.

7.

Chloroquine binding reveals flavin redox switch function of quinone reductase 2.

Leung KK, Shilton BH.

J Biol Chem. 2013 Apr 19;288(16):11242-51. doi: 10.1074/jbc.M113.457002. Epub 2013 Mar 7.

8.

Nitazoxanide stimulates autophagy and inhibits mTORC1 signaling and intracellular proliferation of Mycobacterium tuberculosis.

Lam KK, Zheng X, Forestieri R, Balgi AD, Nodwell M, Vollett S, Anderson HJ, Andersen RJ, Av-Gay Y, Roberge M.

PLoS Pathog. 2012;8(5):e1002691. doi: 10.1371/journal.ppat.1002691. Epub 2012 May 10.

9.

MG132 inhibition of proteasome blocks apoptosis induced by severe DNA damage.

Zhang L, Hu JJ, Gong F.

Cell Cycle. 2011 Oct 15;10(20):3515-8. doi: 10.4161/cc.10.20.17789. Epub 2011 Oct 15.

10.

Split T cell tolerance against a self/tumor antigen: spontaneous CD4+ but not CD8+ T cell responses against p53 in cancer patients and healthy donors.

Tsuji T, Matsuzaki J, Ritter E, Miliotto A, Ritter G, Odunsi K, Old LJ, Gnjatic S.

PLoS One. 2011;6(8):e23651. doi: 10.1371/journal.pone.0023651. Epub 2011 Aug 12.

11.

Dimer formation and conformational flexibility ensure cytoplasmic stability and nuclear accumulation of Elk-1.

Evans EL, Saxton J, Shelton SJ, Begitt A, Holliday ND, Hipskind RA, Shaw PE.

Nucleic Acids Res. 2011 Aug;39(15):6390-402. doi: 10.1093/nar/gkr266. Epub 2011 May 4.

12.

A small ribosomal subunit (SSU) processome component, the human U3 protein 14A (hUTP14A) binds p53 and promotes p53 degradation.

Hu L, Wang J, Liu Y, Zhang Y, Zhang L, Kong R, Zheng Z, Du X, Ke Y.

J Biol Chem. 2011 Jan 28;286(4):3119-28. doi: 10.1074/jbc.M110.157842. Epub 2010 Nov 15.

13.

c-Fos proteasomal degradation is activated by a default mechanism, and its regulation by NAD(P)H:quinone oxidoreductase 1 determines c-Fos serum response kinetics.

Adler J, Reuven N, Kahana C, Shaul Y.

Mol Cell Biol. 2010 Aug;30(15):3767-78. doi: 10.1128/MCB.00899-09. Epub 2010 May 24.

14.

Tau protein degradation is catalyzed by the ATP/ubiquitin-independent 20S proteasome under normal cell conditions.

Grune T, Botzen D, Engels M, Voss P, Kaiser B, Jung T, Grimm S, Ermak G, Davies KJ.

Arch Biochem Biophys. 2010 Aug 15;500(2):181-8. doi: 10.1016/j.abb.2010.05.008. Epub 2010 May 15.

15.

Harmonic oscillations in homeostatic controllers: Dynamics of the p53 regulatory system.

Jolma IW, Ni XY, Rensing L, Ruoff P.

Biophys J. 2010 Mar 3;98(5):743-52. doi: 10.1016/j.bpj.2009.11.013.

16.
17.

Non-proteolytic regulation of p53-mediated transcription through destabilization of the activator.promoter complex by the proteasomal ATPases.

Kim YC, Wu SY, Lim HS, Chiang CM, Kodadek T.

J Biol Chem. 2009 Dec 11;284(50):34522-30. doi: 10.1074/jbc.M109.017277. Epub 2009 Oct 21.

18.

Effects of stability on the biological function of p53.

Khoo KH, Mayer S, Fersht AR.

J Biol Chem. 2009 Nov 6;284(45):30974-80. doi: 10.1074/jbc.M109.033183. Epub 2009 Aug 21.

19.

Hypoxia-inducible factor prolyl-4-hydroxylase PHD2 protein abundance depends on integral membrane anchoring of FKBP38.

Barth S, Edlich F, Berchner-Pfannschmidt U, Gneuss S, Jahreis G, Hasgall PA, Fandrey J, Wenger RH, Camenisch G.

J Biol Chem. 2009 Aug 21;284(34):23046-58. doi: 10.1074/jbc.M109.032631. Epub 2009 Jun 22.

20.

Proteasomes can degrade a significant proportion of cellular proteins independent of ubiquitination.

Baugh JM, Viktorova EG, Pilipenko EV.

J Mol Biol. 2009 Feb 27;386(3):814-27. doi: 10.1016/j.jmb.2008.12.081. Epub 2009 Jan 8.

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