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Items: 1 to 20 of 58

1.

The Hsp70/Hsp90 Chaperone Machinery in Neurodegenerative Diseases.

Lackie RE, Maciejewski A, Ostapchenko VG, Marques-Lopes J, Choy WY, Duennwald ML, Prado VF, Prado MAM.

Front Neurosci. 2017 May 16;11:254. doi: 10.3389/fnins.2017.00254. eCollection 2017. Review.

2.

From the baker to the bedside: yeast models of Parkinson's disease.

Menezes R, Tenreiro S, Macedo D, Santos CN, Outeiro TF.

Microb Cell. 2015 Jul 27;2(8):262-279. doi: 10.15698/mic2015.08.219. Review.

3.

Cellular Regulation of Amyloid Formation in Aging and Disease.

Stroo E, Koopman M, Nollen EA, Mata-Cabana A.

Front Neurosci. 2017 Feb 14;11:64. doi: 10.3389/fnins.2017.00064. eCollection 2017. Review.

4.

Hormetic heat stress and HSF-1 induce autophagy to improve survival and proteostasis in C. elegans.

Kumsta C, Chang JT, Schmalz J, Hansen M.

Nat Commun. 2017 Feb 15;8:14337. doi: 10.1038/ncomms14337.

5.

Chemical Compensation of Mitochondrial Phospholipid Depletion in Yeast and Animal Models of Parkinson's Disease.

Wang S, Zhang S, Xu C, Barron A, Galiano F, Patel D, Lee YJ, Caldwell GA, Caldwell KA, Witt SN.

PLoS One. 2016 Oct 13;11(10):e0164465. doi: 10.1371/journal.pone.0164465. eCollection 2016.

6.

C-Terminal Tyrosine Residue Modifications Modulate the Protective Phosphorylation of Serine 129 of α-Synuclein in a Yeast Model of Parkinson's Disease.

Kleinknecht A, Popova B, Lázaro DF, Pinho R, Valerius O, Outeiro TF, Braus GH.

PLoS Genet. 2016 Jun 24;12(6):e1006098. doi: 10.1371/journal.pgen.1006098. eCollection 2016 Jun.

7.

Hsp90-Associated Immunophilin Homolog Cpr7 Is Required for the Mitotic Stability of [URE3] Prion in Saccharomyces cerevisiae.

Kumar N, Gaur D, Gupta A, Puri A, Sharma D.

PLoS Genet. 2015 Oct 16;11(10):e1005567. doi: 10.1371/journal.pgen.1005567. eCollection 2015 Oct.

8.

Absence of the Yeast Hsp31 Chaperones of the DJ-1 Superfamily Perturbs Cytoplasmic Protein Quality Control in Late Growth Phase.

Amm I, Norell D, Wolf DH.

PLoS One. 2015 Oct 14;10(10):e0140363. doi: 10.1371/journal.pone.0140363. eCollection 2015.

9.

Hsp31 Is a Stress Response Chaperone That Intervenes in the Protein Misfolding Process.

Tsai CJ, Aslam K, Drendel HM, Asiago JM, Goode KM, Paul LN, Rochet JC, Hazbun TR.

J Biol Chem. 2015 Oct 9;290(41):24816-34. doi: 10.1074/jbc.M115.678367. Epub 2015 Aug 25.

10.

Comparative transcriptome profiling of Pyropia yezoensis (Ueda) M.S. Hwang & H.G. Choi in response to temperature stresses.

Sun P, Mao Y, Li G, Cao M, Kong F, Wang L, Bi G.

BMC Genomics. 2015 Jun 17;16:463. doi: 10.1186/s12864-015-1586-1.

11.

Posttranslational Modifications and Clearing of α-Synuclein Aggregates in Yeast.

Popova B, Kleinknecht A, Braus GH.

Biomolecules. 2015 Apr 23;5(2):617-34. doi: 10.3390/biom5020617. Review.

12.

Ubiquitin-dependent proteolysis in yeast cells expressing neurotoxic proteins.

Braun RJ.

Front Mol Neurosci. 2015 Mar 12;8:8. doi: 10.3389/fnmol.2015.00008. eCollection 2015. Review.

13.

Targeting Hsp90/Hsp70-based protein quality control for treatment of adult onset neurodegenerative diseases.

Pratt WB, Gestwicki JE, Osawa Y, Lieberman AP.

Annu Rev Pharmacol Toxicol. 2015;55:353-71. doi: 10.1146/annurev-pharmtox-010814-124332. Epub 2014 Sep 25. Review.

14.

Chaperone-dependent Neurodegeneration: A Molecular Perspective on Therapeutic Intervention.

Carman A, Kishinevsky S, Koren J 3rd, Lou W, Chiosis G.

J Alzheimers Dis Parkinsonism. 2013 Apr;2013(Suppl 10). pii: 007.

15.

Chaperones ameliorate beta cell dysfunction associated with human islet amyloid polypeptide overexpression.

Cadavez L, Montane J, Alcarraz-Vizán G, Visa M, Vidal-Fàbrega L, Servitja JM, Novials A.

PLoS One. 2014 Jul 10;9(7):e101797. doi: 10.1371/journal.pone.0101797. eCollection 2014.

16.

Heat shock protein-70 (Hsp-70) suppresses paraquat-induced neurodegeneration by inhibiting JNK and caspase-3 activation in Drosophila model of Parkinson's disease.

Shukla AK, Pragya P, Chaouhan HS, Tiwari AK, Patel DK, Abdin MZ, Chowdhuri DK.

PLoS One. 2014 Jun 2;9(6):e98886. doi: 10.1371/journal.pone.0098886. eCollection 2014.

17.

Genome-wide analysis of Saccharomyces cerevisiae identifies cellular processes affecting intracellular aggregation of Alzheimer's amyloid-β42: importance of lipid homeostasis.

Nair S, Traini M, Dawes IW, Perrone GG.

Mol Biol Cell. 2014 Aug 1;25(15):2235-49. doi: 10.1091/mbc.E13-04-0216. Epub 2014 May 28.

18.

Chronic treatment with novel small molecule Hsp90 inhibitors rescues striatal dopamine levels but not α-synuclein-induced neuronal cell loss.

McFarland NR, Dimant H, Kibuuka L, Ebrahimi-Fakhari D, Desjardins CA, Danzer KM, Danzer M, Fan Z, Schwarzschild MA, Hirst W, McLean PJ.

PLoS One. 2014 Jan 20;9(1):e86048. doi: 10.1371/journal.pone.0086048. eCollection 2014.

19.

Targeting heat shock proteins to modulate α-synuclein toxicity.

Jones DR, Moussaud S, McLean P.

Ther Adv Neurol Disord. 2014 Jan;7(1):33-51. doi: 10.1177/1756285613493469. Review.

20.

Molecular chaperones and protein folding as therapeutic targets in Parkinson's disease and other synucleinopathies.

Ebrahimi-Fakhari D, Saidi LJ, Wahlster L.

Acta Neuropathol Commun. 2013 Dec 5;1:79. doi: 10.1186/2051-5960-1-79. Review.

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