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Items: 1 to 20 of 24

1.

Positive feedback loop mediated by protein phosphatase 1α mobilization of P-TEFb and basal CDK1 drives androgen receptor in prostate cancer.

Liu X, Gao Y, Ye H, Gerrin S, Ma F, Wu Y, Zhang T, Russo J, Cai C, Yuan X, Liu J, Chen S, Balk SP.

Nucleic Acids Res. 2017 Apr 20;45(7):3738-3751. doi: 10.1093/nar/gkw1291.

PMID:
28062857
2.

Protein Phosphatase-1 Regulates Expression of Neuregulin-1.

Ammosova T, Washington K, Rotimi J, Kumari N, Smith KA, Niu X, Jerebtsova M, Nekhai S.

Biology (Basel). 2016 Dec 2;5(4). pii: E49.

PMID:
27918433
3.

P-TEFb goes viral.

Zaborowska J, Isa NF, Murphy S.

Inside Cell. 2016 Apr;1(2):106-116. Epub 2015 Nov 25. Review.

PMID:
27398404
4.

PP2A as a master regulator of the cell cycle.

Wlodarchak N, Xing Y.

Crit Rev Biochem Mol Biol. 2016 May-Jun;51(3):162-84. doi: 10.3109/10409238.2016.1143913. Epub 2016 Feb 24. Review.

PMID:
26906453
5.

Role of protein phosphatase 1 in dephosphorylation of Ebola virus VP30 protein and its targeting for the inhibition of viral transcription.

Ilinykh PA, Tigabu B, Ivanov A, Ammosova T, Obukhov Y, Garron T, Kumari N, Kovalskyy D, Platonov MO, Naumchik VS, Freiberg AN, Nekhai S, Bukreyev A.

J Biol Chem. 2014 Aug 15;289(33):22723-38. doi: 10.1074/jbc.M114.575050. Epub 2014 Jun 16.

PMID:
24936058
6.

Regulation of CDK9 activity by phosphorylation and dephosphorylation.

Nekhai S, Petukhov M, Breuer D.

Biomed Res Int. 2014;2014:964964. doi: 10.1155/2014/964964. Epub 2014 Jan 12. Review.

PMID:
24524087
7.

Transcription factors mediate the enzymatic disassembly of promoter-bound 7SK snRNP to locally recruit P-TEFb for transcription elongation.

McNamara RP, McCann JL, Gudipaty SA, D'Orso I.

Cell Rep. 2013 Dec 12;5(5):1256-68. doi: 10.1016/j.celrep.2013.11.003. Epub 2013 Dec 5.

PMID:
24316072
8.

Transcription factor Sp3 represses expression of p21CIP¹ via inhibition of productive elongation by RNA polymerase II.

Valin A, Ouyang J, Gill G.

Mol Cell Biol. 2013 Apr;33(8):1582-93. doi: 10.1128/MCB.00323-12. Epub 2013 Feb 11.

PMID:
23401853
9.

Nucleolar protein trafficking in response to HIV-1 Tat: rewiring the nucleolus.

Jarboui MA, Bidoia C, Woods E, Roe B, Wynne K, Elia G, Hall WW, Gautier VW.

PLoS One. 2012;7(11):e48702. doi: 10.1371/journal.pone.0048702. Epub 2012 Nov 15.

PMID:
23166591
10.

Small molecules targeted to a non-catalytic "RVxF" binding site of protein phosphatase-1 inhibit HIV-1.

Ammosova T, Platonov M, Yedavalli VR, Obukhov Y, Gordeuk VR, Jeang KT, Kovalskyy D, Nekhai S.

PLoS One. 2012;7(6):e39481. doi: 10.1371/journal.pone.0039481. Epub 2012 Jun 29.

PMID:
22768081
11.

Mechanisms of HIV Transcriptional Regulation and Their Contribution to Latency.

Schiralli Lester GM, Henderson AJ.

Mol Biol Int. 2012;2012:614120. doi: 10.1155/2012/614120. Epub 2012 Jun 3.

PMID:
22701796
12.

Sickle cell disease is associated with decreased HIV but higher HBV and HCV comorbidities in U.S. hospital discharge records: a cross-sectional study.

Nouraie M, Nekhai S, Gordeuk VR.

Sex Transm Infect. 2012 Nov;88(7):528-33. doi: 10.1136/sextrans-2011-050459. Epub 2012 May 24.

PMID:
22628662
13.

Dual function of histone H3 lysine 36 methyltransferase ASH1 in regulation of Hox gene expression.

Tanaka Y, Kawahashi K, Katagiri Z, Nakayama Y, Mahajan M, Kioussis D.

PLoS One. 2011;6(11):e28171. doi: 10.1371/journal.pone.0028171. Epub 2011 Nov 28.

PMID:
22140534
14.

Protein phosphatase-1 activates CDK9 by dephosphorylating Ser175.

Ammosova T, Obukhov Y, Kotelkin A, Breuer D, Beullens M, Gordeuk VR, Bollen M, Nekhai S.

PLoS One. 2011 Apr 21;6(4):e18985. doi: 10.1371/journal.pone.0018985.

PMID:
21533037
15.

Curing HIV: Pharmacologic approaches to target HIV-1 latency.

Choudhary SK, Margolis DM.

Annu Rev Pharmacol Toxicol. 2011;51:397-418. doi: 10.1146/annurev-pharmtox-010510-100237. Review.

PMID:
21210747
16.

Expression of a protein phosphatase 1 inhibitor, cdNIPP1, increases CDK9 threonine 186 phosphorylation and inhibits HIV-1 transcription.

Ammosova T, Yedavalli VR, Niu X, Jerebtsova M, Van Eynde A, Beullens M, Bollen M, Jeang KT, Nekhai S.

J Biol Chem. 2011 Feb 4;286(5):3798-804. doi: 10.1074/jbc.M110.196493. Epub 2010 Nov 22.

PMID:
21098020
17.

Proteomic analyses of the effects of drugs of abuse on monocyte-derived mature dendritic cells.

Reynolds JL, Mahajan SD, Aalinkeel R, Nair B, Sykes DE, Schwartz SA.

Immunol Invest. 2009;38(6):526-50.

PMID:
19811410
18.

Transcriptional restriction of human immunodeficiency virus type 1 gene expression in undifferentiated primary monocytes.

Dong C, Kwas C, Wu L.

J Virol. 2009 Apr;83(8):3518-27. doi: 10.1128/JVI.02665-08. Epub 2009 Feb 11.

PMID:
19211771
19.

Bromodomain protein Brd4 regulates human immunodeficiency virus transcription through phosphorylation of CDK9 at threonine 29.

Zhou M, Huang K, Jung KJ, Cho WK, Klase Z, Kashanchi F, Pise-Masison CA, Brady JN.

J Virol. 2009 Jan;83(2):1036-44. doi: 10.1128/JVI.01316-08. Epub 2008 Oct 29.

PMID:
18971272
20.

Phosphatase PPM1A regulates phosphorylation of Thr-186 in the Cdk9 T-loop.

Wang Y, Dow EC, Liang YY, Ramakrishnan R, Liu H, Sung TL, Lin X, Rice AP.

J Biol Chem. 2008 Nov 28;283(48):33578-84. doi: 10.1074/jbc.M807495200. Epub 2008 Oct 1.

PMID:
18829461

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