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Conjugate Vaccine Immunotherapy for Substance Use Disorder.

Bremer PT, Janda KD.

Pharmacol Rev. 2017 Jul;69(3):298-315. doi: 10.1124/pr.117.013904. Review.


The effects of a repeated dose of a recombinant humanized anti-cocaine monoclonal antibody on cocaine self-administration in rats.

Wetzel HN, Tsibulsky VL, Norman AB.

Drug Alcohol Depend. 2016 Nov 1;168:287-292. doi: 10.1016/j.drugalcdep.2016.09.024. Epub 2016 Oct 6.


The Health Effect of Psychostimulants: A Literature Review.

Favrod-Coune T, Broers B.

Pharmaceuticals (Basel). 2010 Jul 22;3(7):2333-2361. Review.


Efficacy of an adenovirus-based anti-cocaine vaccine to reduce cocaine self-administration and reacqusition using a choice procedure in rhesus macaques.

Evans SM, Foltin RW, Hicks MJ, Rosenberg JB, De BP, Janda KD, Kaminsky SM, Crystal RG.

Pharmacol Biochem Behav. 2016 Nov - Dec;150-151:76-86. doi: 10.1016/j.pbb.2016.09.008. Epub 2016 Sep 30.


Combatting Synthetic Designer Opioids: A Conjugate Vaccine Ablates Lethal Doses of Fentanyl Class Drugs.

Bremer PT, Kimishima A, Schlosburg JE, Zhou B, Collins KC, Janda KD.

Angew Chem Int Ed Engl. 2016 Mar 7;55(11):3772-5. doi: 10.1002/anie.201511654. Epub 2016 Feb 16.


Addiction pharmacogenetics: a systematic review of the genetic variation of the dopaminergic system.

Patriquin MA, Bauer IE, Soares JC, Graham DP, Nielsen DA.

Psychiatr Genet. 2015 Oct;25(5):181-93. doi: 10.1097/YPG.0000000000000095. Review.


Flagellin as carrier and adjuvant in cocaine vaccine development.

Lockner JW, Eubanks LM, Choi JL, Lively JM, Schlosburg JE, Collins KC, Globisch D, Rosenfeld-Gunn RJ, Wilson IA, Janda KD.

Mol Pharm. 2015 Feb 2;12(2):653-62. doi: 10.1021/mp500520r. Epub 2015 Jan 7.


Attenuation of cocaine-induced locomotor activity in male and female mice by active immunization.

Kosten TA, Shen XY, Kinsey BM, Kosten TR, Orson FM.

Am J Addict. 2014 Nov-Dec;23(6):604-7. doi: 10.1111/j.1521-0391.2014.12152.x. Epub 2014 Sep 22.


Vaccines against drugs of abuse: where are we now?

Kinsey B.

Ther Adv Vaccines. 2014 Jul;2(4):106-17. doi: 10.1177/2051013614537818. Review.


The future potential for cocaine vaccines.

Orson FM, Wang R, Brimijoin S, Kinsey BM, Singh RA, Ramakrishnan M, Wang HY, Kosten TR.

Expert Opin Biol Ther. 2014 Sep;14(9):1271-83. doi: 10.1517/14712598.2014.920319. Epub 2014 May 16. Review.


Hapten optimization for cocaine vaccine with improved cocaine recognition.

Ramakrishnan M, Kinsey BM, Singh RA, Kosten TR, Orson FM.

Chem Biol Drug Des. 2014 Sep;84(3):354-63. doi: 10.1111/cbdd.12326. Epub 2014 Jul 29.


Vaccine for cocaine dependence: a randomized double-blind placebo-controlled efficacy trial.

Kosten TR, Domingo CB, Shorter D, Orson F, Green C, Somoza E, Sekerka R, Levin FR, Mariani JJ, Stitzer M, Tompkins DA, Rotrosen J, Thakkar V, Smoak B, Kampman K.

Drug Alcohol Depend. 2014 Jul 1;140:42-7. doi: 10.1016/j.drugalcdep.2014.04.003. Epub 2014 Apr 16.


A recombinant humanized anti-cocaine monoclonal antibody inhibits the distribution of cocaine to the brain in rats.

Norman AB, Gooden FC, Tabet MR, Ball WJ.

Drug Metab Dispos. 2014 Jul;42(7):1125-31. doi: 10.1124/dmd.114.057034. Epub 2014 Apr 14.


Psychostimulant addiction treatment.

Phillips KA, Epstein DH, Preston KL.

Neuropharmacology. 2014 Dec;87:150-60. doi: 10.1016/j.neuropharm.2014.04.002. Epub 2014 Apr 12. Review.


The κ-opioid receptor gene as a predictor of response in a cocaine vaccine clinical trial.

Nielsen DA, Hamon SC, Kosten TR.

Psychiatr Genet. 2013 Dec;23(6):225-32. doi: 10.1097/YPG.0000000000000008.


Probing the effects of hapten stability on cocaine vaccine immunogenicity.

Cai X, Whitfield T, Moreno AY, Grant Y, Hixon MS, Koob GF, Janda KD.

Mol Pharm. 2013 Nov 4;10(11):4176-84. doi: 10.1021/mp400214w. Epub 2013 Oct 4.


Vaccination protects rats from methamphetamine-induced impairment of behavioral responding for food.

Rüedi-Bettschen D, Wood SL, Gunnell MG, West CM, Pidaparthi RR, Carroll FI, Blough BE, Owens SM.

Vaccine. 2013 Sep 23;31(41):4596-602. doi: 10.1016/j.vaccine.2013.07.038. Epub 2013 Jul 29.


Gene transfer of mutant mouse cholinesterase provides high lifetime expression and reduced cocaine responses with no evident toxicity.

Geng L, Gao Y, Chen X, Hou S, Zhan CG, Radic Z, Parks RJ, Russell SJ, Pham L, Brimijoin S.

PLoS One. 2013 Jun 28;8(6):e67446. doi: 10.1371/journal.pone.0067446. Print 2013.


Dynamic vaccine blocks relapse to compulsive intake of heroin.

Schlosburg JE, Vendruscolo LF, Bremer PT, Lockner JW, Wade CL, Nunes AA, Stowe GN, Edwards S, Janda KD, Koob GF.

Proc Natl Acad Sci U S A. 2013 May 28;110(22):9036-41. doi: 10.1073/pnas.1219159110. Epub 2013 May 6.


Preventing sin: the ethics of vaccines against smoking.

Lieber SR, Millum J.

Hastings Cent Rep. 2013 May-Jun;43(3):23-33. doi: 10.1002/hast.159. No abstract available.

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