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STAT3 promotes IFNγ/TNFα-induced muscle wasting in an NF-κB-dependent and IL-6-independent manner.

Ma JF, Sanchez BJ, Hall DT, Tremblay AK, Di Marco S, Gallouzi IE.

EMBO Mol Med. 2017 May;9(5):622-637. doi: 10.15252/emmm.201607052.


Down-regulation of common NFκB-iNOS pathway by chronic Thalidomide treatment improves Hepatopulmonary Syndrome and Muscle Wasting in rats with Biliary Cirrhosis.

Li TH, Lee PC, Lee KC, Hsieh YC, Tsai CY, Yang YY, Huang SF, Tsai TH, Hsieh SL, Hou MC, Lin HC, Lee SD.

Sci Rep. 2016 Dec 23;6:39405. doi: 10.1038/srep39405.


The Janus-Faced Role of Antioxidants in Cancer Cachexia: New Insights on the Established Concepts.

Assi M, Rébillard A.

Oxid Med Cell Longev. 2016;2016:9579868. doi: 10.1155/2016/9579868. Epub 2016 Aug 24. Review.


Role of Inflammation in Muscle Homeostasis and Myogenesis.

Costamagna D, Costelli P, Sampaolesi M, Penna F.

Mediators Inflamm. 2015;2015:805172. doi: 10.1155/2015/805172. Epub 2015 Oct 5. Review.


Lewis lung carcinoma regulation of mechanical stretch-induced protein synthesis in cultured myotubes.

Gao S, Carson JA.

Am J Physiol Cell Physiol. 2016 Jan 1;310(1):C66-79. doi: 10.1152/ajpcell.00052.2015. Epub 2015 Oct 21.


Large Polyglutamine Repeats Cause Muscle Degeneration in SCA17 Mice.

Huang S, Yang S, Guo J, Yan S, Gaertig MA, Li S, Li XJ.

Cell Rep. 2015 Oct 6;13(1):196-208. doi: 10.1016/j.celrep.2015.08.060. Epub 2015 Sep 17.


Impaired regeneration: A role for the muscle microenvironment in cancer cachexia.

Talbert EE, Guttridge DC.

Semin Cell Dev Biol. 2016 Jun;54:82-91. doi: 10.1016/j.semcdb.2015.09.009. Epub 2015 Sep 16. Review.


Long noncoding RNAs in diseases of aging.

Kim J, Kim KM, Noh JH, Yoon JH, Abdelmohsen K, Gorospe M.

Biochim Biophys Acta. 2016 Jan;1859(1):209-21. doi: 10.1016/j.bbagrm.2015.06.013. Epub 2015 Jul 2. Review.


Inflammatory stimuli induce inhibitory S-nitrosylation of the deacetylase SIRT1 to increase acetylation and activation of p53 and p65.

Shinozaki S, Chang K, Sakai M, Shimizu N, Yamada M, Tanaka T, Nakazawa H, Ichinose F, Yamada Y, Ishigami A, Ito H, Ouchi Y, Starr ME, Saito H, Shimokado K, Stamler JS, Kaneki M.

Sci Signal. 2014 Nov 11;7(351):ra106. doi: 10.1126/scisignal.2005375.


Skeletal muscle myofilament adaptations to aging, disease, and disuse and their effects on whole muscle performance in older adult humans.

Miller MS, Callahan DM, Toth MJ.

Front Physiol. 2014 Sep 26;5:369. doi: 10.3389/fphys.2014.00369. eCollection 2014. Review.


Destabilization of nucleophosmin mRNA by the HuR/KSRP complex is required for muscle fibre formation.

Cammas A, Sanchez BJ, Lian XJ, Dormoy-Raclet V, van der Giessen K, López de Silanes I, Ma J, Wilusz C, Richardson J, Gorospe M, Millevoi S, Giovarelli M, Gherzi R, Di Marco S, Gallouzi IE.

Nat Commun. 2014 Jun 27;5:4190. doi: 10.1038/ncomms5190.


Trans-regulation of RNA-binding protein motifs by microRNA.

Doyle F, Tenenbaum SA.

Front Genet. 2014 Apr 15;5:79. doi: 10.3389/fgene.2014.00079. eCollection 2014.


TNF- α and IFN-s-dependent muscle decay is linked to NF-κB- and STAT-1α-stimulated Atrogin1 and MuRF1 genes in C2C12 myotubes.

Pijet B, Pijet M, Litwiniuk A, Gajewska M, Pająk B, Orzechowski A.

Mediators Inflamm. 2013;2013:171437. doi: 10.1155/2013/171437. Epub 2013 Dec 17.


AMPK activation--protean potential for boosting healthspan.

McCarty MF.

Age (Dordr). 2014 Apr;36(2):641-63. doi: 10.1007/s11357-013-9595-y. Epub 2013 Nov 19. Review.


HuR and miR-1192 regulate myogenesis by modulating the translation of HMGB1 mRNA.

Dormoy-Raclet V, Cammas A, Celona B, Lian XJ, van der Giessen K, Zivojnovic M, Brunelli S, Riuzzi F, Sorci G, Wilhelm BT, Di Marco S, Donato R, Bianchi ME, Gallouzi IE.

Nat Commun. 2013;4:2388. doi: 10.1038/ncomms3388.


AMP-activated protein kinase (AMPK)α2 plays a role in determining the cellular fate of glucose in insulin-resistant mouse skeletal muscle.

Lee-Young RS, Bonner JS, Mayes WH, Iwueke I, Barrick BA, Hasenour CM, Kang L, Wasserman DH.

Diabetologia. 2013 Mar;56(3):608-17. doi: 10.1007/s00125-012-2787-7. Epub 2012 Dec 8.


Apoptotic-induced cleavage shifts HuR from being a promoter of survival to an activator of caspase-mediated apoptosis.

von Roretz C, Lian XJ, Macri AM, Punjani N, Clair E, Drouin O, Dormoy-Raclet V, Ma JF, Gallouzi IE.

Cell Death Differ. 2013 Jan;20(1):154-68. doi: 10.1038/cdd.2012.111. Epub 2012 Sep 7.


The translation inhibitor pateamine A prevents cachexia-induced muscle wasting in mice.

Di Marco S, Cammas A, Lian XJ, Kovacs EN, Ma JF, Hall DT, Mazroui R, Richardson J, Pelletier J, Gallouzi IE.

Nat Commun. 2012 Jun 12;3:896. doi: 10.1038/ncomms1899.


Molecular and cellular mechanisms of skeletal muscle atrophy: an update.

Fanzani A, Conraads VM, Penna F, Martinet W.

J Cachexia Sarcopenia Muscle. 2012 Sep;3(3):163-79. doi: 10.1007/s13539-012-0074-6. Epub 2012 Jun 7.


Late-life enalapril administration induces nitric oxide-dependent and independent metabolic adaptations in the rat skeletal muscle.

Marzetti E, Calvani R, DuPree J, Lees HA, Giovannini S, Seo DO, Buford TW, Sweet K, Morgan D, Strehler KY, Diz D, Borst SE, Moningka N, Krotova K, Carter CS.

Age (Dordr). 2013 Aug;35(4):1061-75. doi: 10.1007/s11357-012-9428-4. Epub 2012 May 26.

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