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A regulatory circuit composed of DNA methyltransferases and receptor tyrosine kinases controls lung cancer cell aggressiveness.

Yan F, Shen N, Pang J, Zhao N, Deng B, Li B, Yang Y, Yang P, Molina JR, Liu S.

Oncogene. 2017 Dec 14;36(50):6919-6928. doi: 10.1038/onc.2017.305. Epub 2017 Sep 4.


Epigenetic Alterations in Human Papillomavirus-Associated Cancers.

Soto D, Song C, McLaughlin-Drubin ME.

Viruses. 2017 Sep 1;9(9). pii: E248. doi: 10.3390/v9090248. Review.


Vitamin E Modifies High-Fat Diet-Induced Increase of DNA Strand Breaks, and Changes in Expression and DNA Methylation of Dnmt1 and MLH1 in C57BL/6J Male Mice.

Remely M, Ferk F, Sterneder S, Setayesh T, Kepcija T, Roth S, Noorizadeh R, Greunz M, Rebhan I, Wagner KH, Knasmüller S, Haslberger A.

Nutrients. 2017 Jun 14;9(6). pii: E607. doi: 10.3390/nu9060607.


p53 is essential for DNA methylation homeostasis in naïve embryonic stem cells, and its loss promotes clonal heterogeneity.

Tovy A, Spiro A, McCarthy R, Shipony Z, Aylon Y, Allton K, Ainbinder E, Furth N, Tanay A, Barton M, Oren M.

Genes Dev. 2017 May 15;31(10):959-972. doi: 10.1101/gad.299198.117. Epub 2017 Jun 12.


Genotype-specific methylation of HPV in cervical intraepithelial neoplasia.

Hsu YW, Huang RL, Su PH, Chen YC, Wang HC, Liao CC, Lai HC.

J Gynecol Oncol. 2017 Jul;28(4):e56. doi: 10.3802/jgo.2017.28.e56.


Expression of the lncRNA Maternally Expressed Gene 3 (MEG3) Contributes to the Control of Lung Cancer Cell Proliferation by the Rb Pathway.

Kruer TL, Dougherty SM, Reynolds L, Long E, de Silva T, Lockwood WW, Clem BF.

PLoS One. 2016 Nov 10;11(11):e0166363. doi: 10.1371/journal.pone.0166363. eCollection 2016.


Chinese Herbal Mixture, Tien-Hsien Liquid, Induces G2/M Cycle Arrest and Radiosensitivity in MCF-7 Human Breast Cancer Cells through Mechanisms Involving DNMT1 and Rad51 Downregulation.

Yao CJ, Chow JM, Yang CM, Kuo HC, Chang CL, Lee HL, Lai IC, Chuang SE, Lai GM.

Evid Based Complement Alternat Med. 2016;2016:3251046. doi: 10.1155/2016/3251046. Epub 2016 Jul 20.


MUC1-C induces DNA methyltransferase 1 and represses tumor suppressor genes in acute myeloid leukemia.

Tagde A, Rajabi H, Stroopinsky D, Gali R, Alam M, Bouillez A, Kharbanda S, Stone R, Avigan D, Kufe D.

Oncotarget. 2016 Jun 28;7(26):38974-38987. doi: 10.18632/oncotarget.9777.


Deoxyribonucleic acid (DNA) methyltransferase contributes to p16 promoter CpG island methylation in lung adenocarcinoma with smoking.

Sun R, Liu J, Wang B, Ma L, Quan X, Chu Z, Li T.

Int J Clin Exp Med. 2015 Sep 15;8(9):15773-9. eCollection 2015.


Dysregulated transcriptional and post-translational control of DNA methyltransferases in cancer.

Lin RK, Wang YC.

Cell Biosci. 2014 Aug 19;4:46. doi: 10.1186/2045-3701-4-46. eCollection 2014. Review.


HIV-1 Tat induces DNMT over-expression through microRNA dysregulation in HIV-related non Hodgkin lymphomas.

Luzzi A, Morettini F, Gazaneo S, Mundo L, Onnis A, Mannucci S, Rogena EA, Bellan C, Leoncini L, De Falco G.

Infect Agent Cancer. 2014 Dec 9;9:41. doi: 10.1186/1750-9378-9-41. eCollection 2014.


Epigenetic regulation of thyroid hormone receptor beta in renal cancer.

Wojcicka A, Piekielko-Witkowska A, Kedzierska H, Rybicka B, Poplawski P, Boguslawska J, Master A, Nauman A.

PLoS One. 2014 May 21;9(5):e97624. doi: 10.1371/journal.pone.0097624. eCollection 2014.


Human papilloma virus, DNA methylation and microRNA expression in cervical cancer (Review).

Jiménez-Wences H, Peralta-Zaragoza O, Fernández-Tilapa G.

Oncol Rep. 2014 Jun;31(6):2467-76. doi: 10.3892/or.2014.3142. Epub 2014 Apr 16.


ATM mediates pRB function to control DNMT1 protein stability and DNA methylation.

Shamma A, Suzuki M, Hayashi N, Kobayashi M, Sasaki N, Nishiuchi T, Doki Y, Okamoto T, Kohno S, Muranaka H, Kitajima S, Yamamoto K, Takahashi C.

Mol Cell Biol. 2013 Aug;33(16):3113-24. doi: 10.1128/MCB.01597-12. Epub 2013 Jun 10.


DNA-demethylating and anti-tumor activity of synthetic miR-29b mimics in multiple myeloma.

Amodio N, Leotta M, Bellizzi D, Di Martino MT, D'Aquila P, Lionetti M, Fabiani F, Leone E, Gullà AM, Passarino G, Caraglia M, Negrini M, Neri A, Giordano A, Tagliaferri P, Tassone P.

Oncotarget. 2012 Oct;3(10):1246-58.


An insight into the various regulatory mechanisms modulating human DNA methyltransferase 1 stability and function.

Kar S, Deb M, Sengupta D, Shilpi A, Parbin S, Torrisani J, Pradhan S, Patra S.

Epigenetics. 2012 Sep;7(9):994-1007. Epub 2012 Aug 16. Review.


Epigenetic mechanisms in virus-induced tumorigenesis.

Poreba E, Broniarczyk JK, Gozdzicka-Jozefiak A.

Clin Epigenetics. 2011 Aug;2(2):233-47. doi: 10.1007/s13148-011-0026-6. Epub 2011 Mar 23.


Embryonic stem cell miRNAs and their roles in development and disease.

Vidigal JA, Ventura A.

Semin Cancer Biol. 2012 Oct;22(5-6):428-36. doi: 10.1016/j.semcancer.2012.04.009. Epub 2012 May 4. Review.


RB: mitotic implications of a tumour suppressor.

Manning AL, Dyson NJ.

Nat Rev Cancer. 2012 Feb 9;12(3):220-6. doi: 10.1038/nrc3216. Review.

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