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Items: 1 to 20 of 93


miR-198 functions as a tumor suppressor in breast cancer by targeting CUB domain-containing protein 1.

Hu Y, Tang Z, Jiang B, Chen J, Fu Z.

Oncol Lett. 2017 Mar;13(3):1753-1760. doi: 10.3892/ol.2017.5673. Epub 2017 Feb 2.


Protein Kinase C as Regulator of Vascular Smooth Muscle Function and Potential Target in Vascular Disorders.

Ringvold HC, Khalil RA.

Adv Pharmacol. 2017;78:203-301. doi: 10.1016/bs.apha.2016.06.002. Epub 2016 Jul 18.


Enzyme kinetics and distinct modulation of the protein kinase N family of kinases by lipid activators and small molecule inhibitors.

Falk MD, Liu W, Bolaños B, Unsal-Kacmaz K, Klippel A, Grant S, Brooun A, Timofeevski S.

Biosci Rep. 2014 Apr 1;34(2). pii: e00097. Print 2014 Apr 1.


Molecular determinants of KA1 domain-mediated autoinhibition and phospholipid activation of MARK1 kinase.

Emptage RP, Lemmon MA, Ferguson KM.

Biochem J. 2017 Feb 1;474(3):385-398. doi: 10.1042/BCJ20160792. Epub 2016 Nov 22.


Receptor tyrosine kinase (c-Kit) inhibitors: a potential therapeutic target in cancer cells.

Abbaspour Babaei M, Kamalidehghan B, Saleem M, Huri HZ, Ahmadipour F.

Drug Des Devel Ther. 2016 Aug 1;10:2443-59. doi: 10.2147/DDDT.S89114. eCollection 2016. Review.


Phos-tag SDS-PAGE resolves agonist- and isoform-specific activation patterns for PKD2 and PKD3 in cardiomyocytes and cardiac fibroblasts.

Qiu W, Steinberg SF.

J Mol Cell Cardiol. 2016 Oct;99:14-22. doi: 10.1016/j.yjmcc.2016.08.005. Epub 2016 Aug 8.


CUB domain-containing protein 1 and the epidermal growth factor receptor cooperate to induce cell detachment.

Law ME, Ferreira RB, Davis BJ, Higgins PJ, Kim JS, Castellano RK, Chen S, Luesch H, Law BK.

Breast Cancer Res. 2016 Aug 5;18(1):80. doi: 10.1186/s13058-016-0741-1.


Protein kinase C mechanisms that contribute to cardiac remodelling.

Newton AC, Antal CE, Steinberg SF.

Clin Sci (Lond). 2016 Sep 1;130(17):1499-510. doi: 10.1042/CS20160036. Review.


Multifunctional roles of PKCδ: Opportunities for targeted therapy in human disease.

Reyland ME, Jones DN.

Pharmacol Ther. 2016 Sep;165:1-13. doi: 10.1016/j.pharmthera.2016.05.001. Epub 2016 May 11. Review.


Spatio-Temporal Regulation of PKC Isoforms Imparts Signaling Specificity.

Mukherjee A, Roy S, Saha B, Mukherjee D.

Front Immunol. 2016 Feb 17;7:45. doi: 10.3389/fimmu.2016.00045. eCollection 2016. Review. No abstract available.


CDCP1 cleavage is necessary for homodimerization-induced migration of triple-negative breast cancer.

Wright HJ, Arulmoli J, Motazedi M, Nelson LJ, Heinemann FS, Flanagan LA, Razorenova OV.

Oncogene. 2016 Sep 8;35(36):4762-72. doi: 10.1038/onc.2016.7. Epub 2016 Feb 15.


A novel phosphorylation site at Ser130 adjacent to the pseudosubstrate domain contributes to the activation of protein kinase C-δ.

Gong J, Holewinski RJ, Van Eyk JE, Steinberg SF.

Biochem J. 2016 Feb 1;473(3):311-20. doi: 10.1042/BJ20150812. Epub 2015 Nov 6.


Dynamics and Membrane Interactions of Protein Kinase C.

Igumenova TI.

Biochemistry. 2015 Aug 18;54(32):4953-68. doi: 10.1021/acs.biochem.5b00565. Epub 2015 Aug 5. Review.


A phosphorylation switch controls the spatiotemporal activation of Rho GTPases in directional cell migration.

Cao X, Kaneko T, Li JS, Liu AD, Voss C, Li SS.

Nat Commun. 2015 Jul 13;6:7721. doi: 10.1038/ncomms8721. Erratum in: Nat Commun. 2015;6:8320.


Mechanisms for redox-regulation of protein kinase C.

Steinberg SF.

Front Pharmacol. 2015 Jun 23;6:128. doi: 10.3389/fphar.2015.00128. eCollection 2015. Review.


AIP1 Expression in Tumor Niche Suppresses Tumor Progression and Metastasis.

Ji W, Li Y, He Y, Yin M, Zhou HJ, Boggon TJ, Zhang H, Min W.

Cancer Res. 2015 Sep 1;75(17):3492-504. doi: 10.1158/0008-5472.CAN-15-0088. Epub 2015 Jul 2.


The tyrosine phosphatase SHP2 associates with CUB domain-containing protein-1 (CDCP1), regulating its expression at the cell surface in a phosphorylation-dependent manner.

Gandji LY, Proust R, Larue L, Gesbert F.

PLoS One. 2015 Apr 13;10(4):e0123472. doi: 10.1371/journal.pone.0123472. eCollection 2015.


The C2 Domain and Altered ATP-Binding Loop Phosphorylation at Ser³⁵⁹ Mediate the Redox-Dependent Increase in Protein Kinase C-δ Activity.

Gong J, Yao Y, Zhang P, Udayasuryan B, Komissarova EV, Chen J, Sivaramakrishnan S, Van Eyk JE, Steinberg SF.

Mol Cell Biol. 2015 May;35(10):1727-40. doi: 10.1128/MCB.01436-14. Epub 2015 Mar 9.


CUB-domain-containing protein 1 overexpression in solid cancers promotes cancer cell growth by activating Src family kinases.

Leroy C, Shen Q, Strande V, Meyer R, McLaughlin ME, Lezan E, Bentires-Alj M, Voshol H, Bonenfant D, Alex Gaither L.

Oncogene. 2015 Oct 29;34(44):5593-8. doi: 10.1038/onc.2015.19. Epub 2015 Mar 2.


Superdomains in the protein structure hierarchy: The case of PTP-C2.

Haynie DT, Xue B.

Protein Sci. 2015 May;24(5):874-82. doi: 10.1002/pro.2664. Epub 2015 Mar 31.

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