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Items: 1 to 20 of 43

1.

Hedgehog Signaling in Pancreatic Fibrosis and Cancer.

Bai Y, Bai Y, Dong J, Li Q, Jin Y, Chen B, Zhou M.

Medicine (Baltimore). 2016 Mar;95(10):e2996. doi: 10.1097/MD.0000000000002996. Review.

2.
3.

Targeting the Hedgehog Pathway in Pediatric Medulloblastoma.

Huang SY, Yang JY.

Cancers (Basel). 2015 Oct 23;7(4):2110-23. doi: 10.3390/cancers7040880. Review.

4.

KIF7 Controls the Proliferation of Cells of the Respiratory Airway through Distinct Microtubule Dependent Mechanisms.

Coles GL, Baglia LA, Ackerman KG.

PLoS Genet. 2015 Oct 6;11(10):e1005525. doi: 10.1371/journal.pgen.1005525. eCollection 2015 Oct.

5.

Identification of a novel actin-dependent signal transducing module allows for the targeted degradation of GLI1.

Schneider P, Bayo-Fina JM, Singh R, Kumar Dhanyamraju P, Holz P, Baier A, Fendrich V, Ramaswamy A, Baumeister S, Martinez ED, Lauth M.

Nat Commun. 2015 Aug 27;6:8023. doi: 10.1038/ncomms9023. Erratum in: Nat Commun. 2015;6:8741.

6.

LncRNA BCAR4 wires up signaling transduction in breast cancer.

Xing Z, Park PK, Lin C, Yang L.

RNA Biol. 2015;12(7):681-9. doi: 10.1080/15476286.2015.1053687.

7.

Casein kinase 1δ is an APC/C(Cdh1) substrate that regulates cerebellar granule cell neurogenesis.

Penas C, Govek EE, Fang Y, Ramachandran V, Daniel M, Wang W, Maloof ME, Rahaim RJ, Bibian M, Kawauchi D, Finkelstein D, Han JL, Long J, Li B, Robbins DJ, Malumbres M, Roussel MF, Roush WR, Hatten ME, Ayad NG.

Cell Rep. 2015 Apr 14;11(2):249-60. doi: 10.1016/j.celrep.2015.03.016. Epub 2015 Apr 2.

8.

Targeted exploration and analysis of large cross-platform human transcriptomic compendia.

Zhu Q, Wong AK, Krishnan A, Aure MR, Tadych A, Zhang R, Corney DC, Greene CS, Bongo LA, Kristensen VN, Charikar M, Li K, Troyanskaya OG.

Nat Methods. 2015 Mar;12(3):211-4, 3 p following 214. doi: 10.1038/nmeth.3249. Epub 2015 Jan 12.

9.

Hedgehog signaling restrains bladder cancer progression by eliciting stromal production of urothelial differentiation factors.

Shin K, Lim A, Zhao C, Sahoo D, Pan Y, Spiekerkoetter E, Liao JC, Beachy PA.

Cancer Cell. 2014 Oct 13;26(4):521-33. doi: 10.1016/j.ccell.2014.09.001.

10.

Clinicopathological correlates of Gli1 expression in a population-based cohort of patients with newly diagnosed bladder cancer.

Sverrisson EF, Zens MS, Fei DL, Andrews A, Schned A, Robbins D, Kelsey KT, Li H, DiRenzo J, Karagas MR, Seigne JD.

Urol Oncol. 2014 Jul;32(5):539-45. doi: 10.1016/j.urolonc.2014.03.006. Epub 2014 May 22.

11.

Distinct cellular origin and genetic requirement of Hedgehog-Gli in postnatal rhabdomyosarcoma genesis.

Rajurkar M, Huang H, Cotton JL, Brooks JK, Sicklick J, McMahon AP, Mao J.

Oncogene. 2014 Nov 13;33(46):5370-8. doi: 10.1038/onc.2013.480. Epub 2013 Nov 25.

12.

PCAF ubiquitin ligase activity inhibits Hedgehog/Gli1 signaling in p53-dependent response to genotoxic stress.

Mazzà D, Infante P, Colicchia V, Greco A, Alfonsi R, Siler M, Antonucci L, Po A, De Smaele E, Ferretti E, Capalbo C, Bellavia D, Canettieri G, Giannini G, Screpanti I, Gulino A, Di Marcotullio L.

Cell Death Differ. 2013 Dec;20(12):1688-97. doi: 10.1038/cdd.2013.120. Epub 2013 Sep 6.

13.

Gli1 transcriptional activity is negatively regulated by AKT2 in neuroblastoma.

Paul P, Volny N, Lee S, Qiao J, Chung DH.

Oncotarget. 2013 Aug;4(8):1149-57.

14.

Hedgehog signaling regulates bladder cancer growth and tumorigenicity.

Fei DL, Sanchez-Mejias A, Wang Z, Flaveny C, Long J, Singh S, Rodriguez-Blanco J, Tokhunts R, Giambelli C, Briegel KJ, Schulz WA, Gandolfi AJ, Karagas M, Zimmers TA, Jorda M, Bejarano P, Capobianco AJ, Robbins DJ.

Cancer Res. 2012 Sep 1;72(17):4449-58. Epub 2012 Jul 19.

15.

Gli1 protein participates in Hedgehog-mediated specification of osteoblast lineage during endochondral ossification.

Hojo H, Ohba S, Yano F, Saito T, Ikeda T, Nakajima K, Komiyama Y, Nakagata N, Suzuki K, Takato T, Kawaguchi H, Chung UI.

J Biol Chem. 2012 May 18;287(21):17860-9. doi: 10.1074/jbc.M112.347716. Epub 2012 Apr 9.

16.

Identification, functional characterization, and pathobiological significance of GLI1 isoforms in human cancers.

Carpenter RL, Lo HW.

Vitam Horm. 2012;88:115-40. doi: 10.1016/B978-0-12-394622-5.00006-7.

17.

Hedgehog pathway and GLI1 isoforms in human cancer.

Carpenter RL, Lo HW.

Discov Med. 2012 Feb;13(69):105-13. Review.

18.

Matching mice to malignancy: molecular subgroups and models of medulloblastoma.

Lau J, Schmidt C, Markant SL, Taylor MD, Wechsler-Reya RJ, Weiss WA.

Childs Nerv Syst. 2012 Apr;28(4):521-32. doi: 10.1007/s00381-012-1704-1. Review.

19.

GLI1 inhibition promotes epithelial-to-mesenchymal transition in pancreatic cancer cells.

Joost S, Almada LL, Rohnalter V, Holz PS, Vrabel AM, Fernandez-Barrena MG, McWilliams RR, Krause M, Fernandez-Zapico ME, Lauth M.

Cancer Res. 2012 Jan 1;72(1):88-99. doi: 10.1158/0008-5472.CAN-10-4621. Epub 2011 Nov 15.

20.

Sequential activation of Snail1 and N-Myc modulates sonic hedgehog-induced transformation of neural cells.

Colvin Wanshura LE, Galvin KE, Ye H, Fernandez-Zapico ME, Wetmore C.

Cancer Res. 2011 Aug 1;71(15):5336-45. doi: 10.1158/0008-5472.CAN-10-2633. Epub 2011 Jun 6.

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