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Items: 1 to 20 of 57


ROCK1 but not ROCK2 contributes to RhoA signaling and NMIIA-mediated contractility at the epithelial zonula adherens.

Priya R, Liang X, Teo JL, Duszyc K, Yap AS, Gomez GA.

Mol Biol Cell. 2017 Jan 1;28(1):12-20. doi: 10.1091/mbc.E16-04-0262. Epub 2016 Nov 9.


Rnd3-induced cell rounding requires interaction with Plexin-B2.

McColl B, Garg R, Riou P, Riento K, Ridley AJ.

J Cell Sci. 2016 Nov 1;129(21):4046-4056. Epub 2016 Sep 21.


Rho GTPases: Regulation and roles in cancer cell biology.

Haga RB, Ridley AJ.

Small GTPases. 2016 Oct;7(4):207-221. Epub 2016 Sep 14. Review.


Membrane bleb: A seesaw game of two small GTPases.

Ikenouchi J, Aoki K.

Small GTPases. 2017 Apr 3;8(2):85-89. doi: 10.1080/21541248.2016.1199266. Epub 2016 Jun 17. Review.


Structural Mechanisms and Drug Discovery Prospects of Rho GTPases.

Smithers CC, Overduin M.

Cells. 2016 Jun 13;5(2). pii: E26. doi: 10.3390/cells5020026. Review.


Made to measure - keeping Rho kinase at a distance.

Truebestein L, Elsner DJ, Leonard TA.

Small GTPases. 2016 Apr 2;7(2):82-92. doi: 10.1080/21541248.2016.1173770. Epub 2016 Apr 12. Review.


Rnd3 as a Novel Target to Ameliorate Microvascular Leakage.

Breslin JW, Daines DA, Doggett TM, Kurtz KH, Souza-Smith FM, Zhang XE, Wu MH, Yuan SY.

J Am Heart Assoc. 2016 Apr 5;5(4):e003336. doi: 10.1161/JAHA.116.003336.


Chaperone-mediated autophagy regulates proliferation by targeting RND3 in gastric cancer.

Zhou J, Yang J, Fan X, Hu S, Zhou F, Dong J, Zhang S, Shang Y, Jiang X, Guo H, Chen N, Xiao X, Sheng J, Wu K, Nie Y, Fan D.

Autophagy. 2016;12(3):515-28. doi: 10.1080/15548627.2015.1136770.


Pathophysiological Functions of Rnd3/RhoE.

Jie W, Andrade KC, Lin X, Yang X, Yue X, Chang J.

Compr Physiol. 2015 Dec 15;6(1):169-86. doi: 10.1002/cphy.c150018. Review.


The Function of Rho-Associated Kinases ROCK1 and ROCK2 in the Pathogenesis of Cardiovascular Disease.

Hartmann S, Ridley AJ, Lutz S.

Front Pharmacol. 2015 Nov 20;6:276. doi: 10.3389/fphar.2015.00276. eCollection 2015. Review.


RhoE is required for contact inhibition and negatively regulates tumor initiation and progression.

Hernández-Sánchez M, Poch E, Guasch RM, Ortega J, López-Almela I, Palmero I, Pérez-Roger I.

Oncotarget. 2015 Jul 10;6(19):17479-90.


Discovery of novel inhibitors for the treatment of glaucoma.

Cholkar K, Trinh HM, Pal D, Mitra AK.

Expert Opin Drug Discov. 2015 Mar;10(3):293-313. doi: 10.1517/17460441.2015.1000857. Epub 2015 Jan 9. Review.


Genetic deletion of Rnd3/RhoE results in mouse heart calcium leakage through upregulation of protein kinase A signaling.

Yang X, Wang T, Lin X, Yue X, Wang Q, Wang G, Fu Q, Ai X, Chiang DY, Miyake CY, Wehrens XHT, Chang J.

Circ Res. 2015 Jan 2;116(1):e1-e10. doi: 10.1161/CIRCRESAHA.116.304940. Epub 2014 Oct 27.


ROCK is involved in vasculogenic mimicry formation in hepatocellular carcinoma cell line.

Zhang JG, Li XY, Wang YZ, Zhang QD, Gu SY, Wu X, Zhu GH, Li Q, Liu GL.

PLoS One. 2014 Sep 19;9(9):e107661. doi: 10.1371/journal.pone.0107661. eCollection 2014.


Rho-associated coiled-coil containing kinases (ROCK): structure, regulation, and functions.

Julian L, Olson MF.

Small GTPases. 2014;5:e29846. doi: 10.4161/sgtp.29846. Epub 2014 Jul 10. Review.


Genetic and physical interaction of Ssp1 CaMKK and Rad24 14-3-3 during low pH and osmotic stress in fission yeast.

Freitag SI, Wong J, Young PG.

Open Biol. 2014 Jan 22;4:130127. doi: 10.1098/rsob.130127.


The Rho family member RhoE interacts with Skp2 and is degraded at the proteasome during cell cycle progression.

Lonjedo M, Poch E, Mocholí E, Hernández-Sánchez M, Ivorra C, Franke TF, Guasch RM, Pérez-Roger I.

J Biol Chem. 2013 Oct 25;288(43):30872-82. doi: 10.1074/jbc.M113.511105. Epub 2013 Sep 17.


Phosphorylation of Rac1 T108 by extracellular signal-regulated kinase in response to epidermal growth factor: a novel mechanism to regulate Rac1 function.

Tong J, Li L, Ballermann B, Wang Z.

Mol Cell Biol. 2013 Nov;33(22):4538-51. doi: 10.1128/MCB.00822-13. Epub 2013 Sep 16.


Rho kinases in cardiovascular physiology and pathophysiology: the effect of fasudil.

Shi J, Wei L.

J Cardiovasc Pharmacol. 2013 Oct;62(4):341-54. doi: 10.1097/FJC.0b013e3182a3718f. Review.


Rho/Rho-associated coiled-coil forming kinase pathway as therapeutic targets for statins in atherosclerosis.

Sawada N, Liao JK.

Antioxid Redox Signal. 2014 Mar 10;20(8):1251-67. doi: 10.1089/ars.2013.5524. Epub 2013 Sep 24. Review.

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