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Items: 1 to 20 of 44

1.

Targeting of Chk2 as a countermeasure to dose-limiting toxicity triggered by topoisomerase-II (TOP2) poisons.

Gokare P, Navaraj A, Zhang S, Motoyama N, Sung SS, Finnberg NK.

Oncotarget. 2016 May 17;7(20):29520-30. doi: 10.18632/oncotarget.8790.

2.

Macrophage-epithelial paracrine crosstalk inhibits lung edema clearance during influenza infection.

Peteranderl C, Morales-Nebreda L, Selvakumar B, Lecuona E, Vadász I, Morty RE, Schmoldt C, Bespalowa J, Wolff T, Pleschka S, Mayer K, Gattenloehner S, Fink L, Lohmeyer J, Seeger W, Sznajder JI, Mutlu GM, Budinger GR, Herold S.

J Clin Invest. 2016 Apr 1;126(4):1566-80. doi: 10.1172/JCI83931. Epub 2016 Mar 21.

3.

TNFSF10/TRAIL regulates human T4 effector memory lymphocyte radiosensitivity and predicts radiation-induced acute and subacute dermatitis.

Baijer J, Déchamps N, Perdry H, Morales P, Kerns S, Vasilescu A, Baulande S, Azria D, Roméo PH, Schmitz A.

Oncotarget. 2016 Apr 19;7(16):21416-27. doi: 10.18632/oncotarget.7893.

4.

Pathophysiological Responses in Rat and Mouse Models of Radiation-Induced Brain Injury.

Yang L, Yang J, Li G, Li Y, Wu R, Cheng J, Tang Y.

Mol Neurobiol. 2017 Mar;54(2):1022-1032. doi: 10.1007/s12035-015-9628-x. Epub 2016 Jan 22. Review.

5.

Alcohol stimulates macrophage activation through caspase-dependent hepatocyte derived release of CD40L containing extracellular vesicles.

Verma VK, Li H, Wang R, Hirsova P, Mushref M, Liu Y, Cao S, Contreras PC, Malhi H, Kamath PS, Gores GJ, Shah VH.

J Hepatol. 2016 Mar;64(3):651-60. doi: 10.1016/j.jhep.2015.11.020. Epub 2015 Nov 26.

6.

Agonists of the TRAIL Death Receptor DR5 Sensitize Intestinal Stem Cells to Chemotherapy-Induced Cell Death and Trigger Gastrointestinal Toxicity.

Finnberg NK, Gokare P, Navaraj A, Lang Kuhs KA, Cerniglia G, Yagita H, Takeda K, Motoyama N, El-Deiry WS.

Cancer Res. 2016 Feb 1;76(3):700-12. doi: 10.1158/0008-5472.CAN-15-2759. Epub 2015 Nov 25.

7.

DDR-mediated crosstalk between DNA-damaged cells and their microenvironment.

Malaquin N, Carrier-Leclerc A, Dessureault M, Rodier F.

Front Genet. 2015 Mar 12;6:94. doi: 10.3389/fgene.2015.00094. eCollection 2015 Mar 12. Review.

8.

TRAIL receptor deletion in mice suppresses the inflammation of nutrient excess.

Idrissova L, Malhi H, Werneburg NW, LeBrasseur NK, Bronk SF, Fingas C, Tchkonia T, Pirtskhalava T, White TA, Stout MB, Hirsova P, Krishnan A, Liedtke C, Trautwein C, Finnberg N, El-Deiry WS, Kirkland JL, Gores GJ.

J Hepatol. 2015 May;62(5):1156-63. doi: 10.1016/j.jhep.2014.11.033. Epub 2014 Nov 28.

9.

ER stress regulates myeloid-derived suppressor cell fate through TRAIL-R-mediated apoptosis.

Condamine T, Kumar V, Ramachandran IR, Youn JI, Celis E, Finnberg N, El-Deiry WS, Winograd R, Vonderheide RH, English NR, Knight SC, Yagita H, McCaffrey JC, Antonia S, Hockstein N, Witt R, Masters G, Bauer T, Gabrilovich DI.

J Clin Invest. 2014 Jun;124(6):2626-39. doi: 10.1172/JCI74056. Epub 2014 May 1.

10.

TRAIL receptor deficiency sensitizes mice to dextran sodium sulphate-induced colitis and colitis-associated carcinogenesis.

Zhu J, Chen L, Shi J, Liu S, Liu Y, Zheng D.

Immunology. 2014 Feb;141(2):211-21. doi: 10.1111/imm.12181.

11.

Degradation of cIAPs contributes to hepatocyte lipoapoptosis.

Akazawa Y, Guicciardi ME, Cazanave SC, Bronk SF, Werneburg NW, Kakisaka K, Nakao K, Gores GJ.

Am J Physiol Gastrointest Liver Physiol. 2013 Nov;305(9):G611-9. doi: 10.1152/ajpgi.00111.2013. Epub 2013 Sep 5.

12.

Mechanisms of radiation toxicity in transformed and non-transformed cells.

Panganiban RA, Snow AL, Day RM.

Int J Mol Sci. 2013 Jul 31;14(8):15931-58. doi: 10.3390/ijms140815931. Review.

13.

Human embryonic and induced pluripotent stem cells express TRAIL receptors and can be sensitized to TRAIL-induced apoptosis.

Vinarsky V, Krivanek J, Rankel L, Nahacka Z, Barta T, Jaros J, Andera L, Hampl A.

Stem Cells Dev. 2013 Nov 15;22(22):2964-74. doi: 10.1089/scd.2013.0057. Epub 2013 Aug 2.

14.

The effects of antioxidants on gene expression following gamma-radiation (GR) and proton radiation (PR) in mice in vivo.

Finnberg N, Wambi C, Kennedy AR, El-Deiry WS.

Cell Cycle. 2013 Jun 20;12(14). [Epub ahead of print]

15.

Adoptively transferred TRAIL+ T cells suppress GVHD and augment antitumor activity.

Ghosh A, Dogan Y, Moroz M, Holland AM, Yim NL, Rao UK, Young LF, Tannenbaum D, Masih D, Velardi E, Tsai JJ, Jenq RR, Penack O, Hanash AM, Smith OM, Piersanti K, Lezcano C, Murphy GF, Liu C, Palomba ML, Sauer MG, Sadelain M, Ponomarev V, van den Brink MR.

J Clin Invest. 2013 Jun;123(6):2654-62. doi: 10.1172/JCI66301. Epub 2013 May 15.

16.

Death receptors as targets in cancer.

Micheau O, Shirley S, Dufour F.

Br J Pharmacol. 2013 Aug;169(8):1723-44. doi: 10.1111/bph.12238. Review.

17.

Macrophage-expressed IFN-β contributes to apoptotic alveolar epithelial cell injury in severe influenza virus pneumonia.

Högner K, Wolff T, Pleschka S, Plog S, Gruber AD, Kalinke U, Walmrath HD, Bodner J, Gattenlöhner S, Lewe-Schlosser P, Matrosovich M, Seeger W, Lohmeyer J, Herold S.

PLoS Pathog. 2013 Feb;9(2):e1003188. doi: 10.1371/journal.ppat.1003188. Epub 2013 Feb 28. Erratum in: PLoS Pathog. 2016 Jun;12(6):e1005716.

18.

Inefficient boosting of antitumor CD8(+) T cells by dendritic-cell vaccines is rescued by restricting T-cell cytotoxic functions.

Zhi-Iong Ma J, Yang J, Qin JS, Richter A, Perret R, El-Deiry WS, Finnberg N, Ronchese F.

Oncoimmunology. 2012 Dec 1;1(9):1507-1516.

19.

TNF-related apoptosis-inducing ligand (TRAIL) exerts therapeutic efficacy for the treatment of pneumococcal pneumonia in mice.

Steinwede K, Henken S, Bohling J, Maus R, Ueberberg B, Brumshagen C, Brincks EL, Griffith TS, Welte T, Maus UA.

J Exp Med. 2012 Oct 22;209(11):1937-52. doi: 10.1084/jem.20120983. Epub 2012 Oct 15.

20.

Regulation of the human TRAIL gene.

Allen JE, El-Deiry WS.

Cancer Biol Ther. 2012 Oct;13(12):1143-51. doi: 10.4161/cbt.21354. Epub 2012 Aug 15. Review.

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