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Items: 1 to 20 of 98

1.

Pannexin- and Connexin-Mediated Intercellular Communication in Platelet Function.

Molica F, Stierlin FB, Fontana P, Kwak BR.

Int J Mol Sci. 2017 Apr 17;18(4). pii: E850. doi: 10.3390/ijms18040850. Review.

2.

New Concepts and Mechanisms of Platelet Activation Signaling.

Estevez B, Du X.

Physiology (Bethesda). 2017 Mar;32(2):162-177. doi: 10.1152/physiol.00020.2016. Review.

PMID:
28228483
3.

The Phosphatidylinositol 3,4,5-trisphosphate (PI(3,4,5)P3) Binder Rasa3 Regulates Phosphoinositide 3-kinase (PI3K)-dependent Integrin αIIbβ3 Outside-in Signaling.

Battram AM, Durrant TN, Agbani EO, Heesom KJ, Paul DS, Piatt R, Poole AW, Cullen PJ, Bergmeier W, Moore SF, Hers I.

J Biol Chem. 2017 Feb 3;292(5):1691-1704. doi: 10.1074/jbc.M116.746867. Epub 2016 Nov 30.

4.

Breaking barriers: insight into the pathogenesis of neovascular age-related macular degeneration.

Wang H, Wittchen ES, Hartnett ME.

Eye Brain. 2011;3:19-28. Epub 2011 Sep 27.

5.

Pdlim7 Regulates Arf6-Dependent Actin Dynamics and Is Required for Platelet-Mediated Thrombosis in Mice.

Urban AE, Quick EO, Miller KP, Krcmery J, Simon HG.

PLoS One. 2016 Oct 28;11(10):e0164042. doi: 10.1371/journal.pone.0164042. eCollection 2016.

6.

Kv7 Channel Activation Underpins EPAC-Dependent Relaxations of Rat Arteries.

Stott JB, Barrese V, Greenwood IA.

Arterioscler Thromb Vasc Biol. 2016 Dec;36(12):2404-2411. Epub 2016 Oct 27.

7.

Vasodilator-Stimulated Phosphoprotein (VASP)-dependent and -independent pathways regulate thrombin-induced activation of Rap1b in platelets.

Benz PM, Laban H, Zink J, Günther L, Walter U, Gambaryan S, Dib K.

Cell Commun Signal. 2016 Sep 13;14(1):21. doi: 10.1186/s12964-016-0144-z.

8.

Retinal pigment epithelial cell expression of active Rap 1a by scAAV2 inhibits choroidal neovascularization.

Wang H, Han X, Bretz CA, Becker S, Gambhir D, Smith GW, Samulski RJ, Wittchen ES, Quilliam LA, Chrzanowska-Wodnicka M, Hartnett ME.

Mol Ther Methods Clin Dev. 2016 Aug 24;3:16056. doi: 10.1038/mtm.2016.56. eCollection 2016.

9.

Mice Expressing Low Levels of CalDAG-GEFI Exhibit Markedly Impaired Platelet Activation With Minor Impact on Hemostasis.

Piatt R, Paul DS, Lee RH, McKenzie SE, Parise LV, Cowley DO, Cooley BC, Bergmeier W.

Arterioscler Thromb Vasc Biol. 2016 Sep;36(9):1838-46. doi: 10.1161/ATVBAHA.116.307874. Epub 2016 Jul 14.

PMID:
27417588
10.

The Rap1-RIAM-talin axis of integrin activation and blood cell function.

Lagarrigue F, Kim C, Ginsberg MH.

Blood. 2016 Jul 28;128(4):479-87. doi: 10.1182/blood-2015-12-638700. Epub 2016 May 20. Review.

PMID:
27207789
11.

CalDAG-GEFI Deficiency Reduces Atherosclerotic Lesion Development in Mice.

Boulaftali Y, Owens AP 3rd, Beale A, Piatt R, Casari C, Lee RH, Conley PB, Paul DS, Mackman N, Bergmeier W.

Arterioscler Thromb Vasc Biol. 2016 May;36(5):792-9. doi: 10.1161/ATVBAHA.115.306347. Epub 2016 Mar 17.

12.

Platelet signaling: a complex interplay between inhibitory and activatory networks.

Bye AP, Unsworth AJ, Gibbins JM.

J Thromb Haemost. 2016 May;14(5):918-30. doi: 10.1111/jth.13302. Epub 2016 Apr 9. Review.

13.

Mechanism of Diapedesis: Importance of the Transcellular Route.

Filippi MD.

Adv Immunol. 2016;129:25-53. doi: 10.1016/bs.ai.2015.09.001. Epub 2015 Oct 14. Review.

14.

Small GTPase Rap1 Is Essential for Mouse Development and Formation of Functional Vasculature.

Chrzanowska-Wodnicka M, White GC 2nd, Quilliam LA, Whitehead KJ.

PLoS One. 2015 Dec 29;10(12):e0145689. doi: 10.1371/journal.pone.0145689. eCollection 2015.

15.

The Rap1-RIAM pathway prefers β2 integrins.

Calderwood DA.

Blood. 2015 Dec 17;126(25):2658-9. doi: 10.1182/blood-2015-09-668962. No abstract available.

16.

Leukocyte transcellular diapedesis: Rap1b is in control.

Filippi MD.

Tissue Barriers. 2015 May 21;3(3):e1052185. doi: 10.1080/21688370.2015.1052185. eCollection 2015 Jul-Sep.

17.

RAP1-GTPase signaling and platelet function.

Stefanini L, Bergmeier W.

J Mol Med (Berl). 2016 Jan;94(1):13-9. doi: 10.1007/s00109-015-1346-3. Epub 2015 Oct 1. Review.

18.

Loss of the Rap1 effector RIAM results in leukocyte adhesion deficiency due to impaired β2 integrin function in mice.

Klapproth S, Sperandio M, Pinheiro EM, Prünster M, Soehnlein O, Gertler FB, Fässler R, Moser M.

Blood. 2015 Dec 17;126(25):2704-12. doi: 10.1182/blood-2015-05-647453. Epub 2015 Sep 3.

19.

Rap1 and its effector RIAM are required for lymphocyte trafficking.

Su W, Wynne J, Pinheiro EM, Strazza M, Mor A, Montenont E, Berger J, Paul DS, Bergmeier W, Gertler FB, Philips MR.

Blood. 2015 Dec 17;126(25):2695-703. doi: 10.1182/blood-2015-05-644104. Epub 2015 Aug 31.

20.

Actin-tethered junctional complexes in angiogenesis and lymphangiogenesis in association with vascular endothelial growth factor.

Zankov DP, Ogita H.

Biomed Res Int. 2015;2015:314178. doi: 10.1155/2015/314178. Epub 2015 Mar 25. Review.

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