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Items: 18


PP2A binds to the LIM domains of lipoma-preferred partner through its PR130/B″ subunit to regulate cell adhesion and migration.

Janssens V, Zwaenepoel K, Rossé C, Petit MM, Goris J, Parker PJ.

J Cell Sci. 2016 Apr 15;129(8):1605-18. doi: 10.1242/jcs.175778.


Kinase-interacting substrate screening is a novel method to identify kinase substrates.

Amano M, Hamaguchi T, Shohag MH, Kozawa K, Kato K, Zhang X, Yura Y, Matsuura Y, Kataoka C, Nishioka T, Kaibuchi K.

J Cell Biol. 2015 Jun 22;209(6):895-912. doi: 10.1083/jcb.201412008.


Biotin ligase tagging identifies proteins proximal to E-cadherin, including lipoma preferred partner, a regulator of epithelial cell-cell and cell-substrate adhesion.

Van Itallie CM, Tietgens AJ, Aponte A, Fredriksson K, Fanning AS, Gucek M, Anderson JM.

J Cell Sci. 2014 Feb 15;127(Pt 4):885-95. doi: 10.1242/jcs.140475.


The N and C termini of ZO-1 are surrounded by distinct proteins and functional protein networks.

Van Itallie CM, Aponte A, Tietgens AJ, Gucek M, Fredriksson K, Anderson JM.

J Biol Chem. 2013 May 10;288(19):13775-88. doi: 10.1074/jbc.M113.466193.


A complex containing LPP and α-actinin mediates TGFβ-induced migration and invasion of ErbB2-expressing breast cancer cells.

Ngan E, Northey JJ, Brown CM, Ursini-Siegel J, Siegel PM.

J Cell Sci. 2013 May 1;126(Pt 9):1981-91. doi: 10.1242/jcs.118315.


Scribble is required for normal epithelial cell-cell contacts and lumen morphogenesis in the mammalian lung.

Yates LL, Schnatwinkel C, Hazelwood L, Chessum L, Paudyal A, Hilton H, Romero MR, Wilde J, Bogani D, Sanderson J, Formstone C, Murdoch JN, Niswander LA, Greenfield A, Dean CH.

Dev Biol. 2013 Jan 15;373(2):267-80. doi: 10.1016/j.ydbio.2012.11.012.


Nucleocytoplasmic shuttling of cytoskeletal proteins: molecular mechanism and biological significance.

Kumeta M, Yoshimura SH, Hejna J, Takeyasu K.

Int J Cell Biol. 2012;2012:494902. doi: 10.1155/2012/494902.


A protein complex of SCRIB, NOS1AP and VANGL1 regulates cell polarity and migration, and is associated with breast cancer progression.

Anastas JN, Biechele TL, Robitaille M, Muster J, Allison KH, Angers S, Moon RT.

Oncogene. 2012 Aug 9;31(32):3696-708. doi: 10.1038/onc.2011.528.


DomPep--a general method for predicting modular domain-mediated protein-protein interactions.

Li L, Zhao B, Du J, Zhang K, Ling CX, Li SS.

PLoS One. 2011;6(10):e25528. doi: 10.1371/journal.pone.0025528.


The mechanism and implications of hScrib regulation of ERK.

Nagasaka K, Massimi P, Pim D, Subbaiah VK, Kranjec C, Nakagawa S, Yano T, Taketani Y, Banks L.

Small GTPases. 2010 Sep;1(2):108-112.


The cytoskeletal regulator zyxin is required for viability in Drosophila melanogaster.

Renfranz PJ, Blankman E, Beckerle MC.

Anat Rec (Hoboken). 2010 Sep;293(9):1455-69. doi: 10.1002/ar.21193.


Tissue polarity-dependent control of mammary epithelial homeostasis and cancer development: an epigenetic perspective.

Lelièvre SA.

J Mammary Gland Biol Neoplasia. 2010 Mar;15(1):49-63. doi: 10.1007/s10911-010-9168-y. Review.


Tumor suppressor scribble regulates assembly of tight junctions in the intestinal epithelium.

Ivanov AI, Young C, Den Beste K, Capaldo CT, Humbert PO, Brennwald P, Parkos CA, Nusrat A.

Am J Pathol. 2010 Jan;176(1):134-45. doi: 10.2353/ajpath.2010.090220.


Cell Adhesion and Transcriptional Activity - Defining the Role of the Novel Protooncogene LPP.

Grunewald TG, Pasedag SM, Butt E.

Transl Oncol. 2009 Aug 18;2(3):107-16.


Lasp1 gene disruption is linked to enhanced cell migration and tumor formation.

Zhang H, Chen X, Bollag WB, Bollag RJ, Sheehan DJ, Chew CS.

Physiol Genomics. 2009 Aug 7;38(3):372-85. doi: 10.1152/physiolgenomics.00048.2009.


Cytoplasmic Ig-domain proteins: cytoskeletal regulators with a role in human disease.

Otey CA, Dixon R, Stack C, Goicoechea SM.

Cell Motil Cytoskeleton. 2009 Aug;66(8):618-34. doi: 10.1002/cm.20385. Review.


The LIM domain protein LPP is a coactivator for the ETS domain transcription factor PEA3.

Guo B, Sallis RE, Greenall A, Petit MM, Jansen E, Young L, Van de Ven WJ, Sharrocks AD.

Mol Cell Biol. 2006 Jun;26(12):4529-38.


The mammalian Scribble polarity protein regulates epithelial cell adhesion and migration through E-cadherin.

Qin Y, Capaldo C, Gumbiner BM, Macara IG.

J Cell Biol. 2005 Dec 19;171(6):1061-71.

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