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Items: 1 to 20 of 30

1.

Childhood Acute Lymphoblastic Leukemia: Progress Through Collaboration.

Pui CH, Yang JJ, Hunger SP, Pieters R, Schrappe M, Biondi A, Vora A, Baruchel A, Silverman LB, Schmiegelow K, Escherich G, Horibe K, Benoit YC, Izraeli S, Yeoh AE, Liang DC, Downing JR, Evans WE, Relling MV, Mullighan CG.

J Clin Oncol. 2015 Sep 20;33(27):2938-48. doi: 10.1200/JCO.2014.59.1636. Epub 2015 Aug 24. Review.

2.

Methotrexate resistance in relation to treatment outcome in childhood acute lymphoblastic leukemia.

Wojtuszkiewicz A, Peters GJ, van Woerden NL, Dubbelman B, Escherich G, Schmiegelow K, Sonneveld E, Pieters R, van de Ven PM, Jansen G, Assaraf YG, Kaspers GJ, Cloos J.

J Hematol Oncol. 2015 May 29;8:61. doi: 10.1186/s13045-015-0158-9.

3.

The flow cytometry-defined light chain cytoplasmic immunoglobulin index and an associated 12-gene expression signature are independent prognostic factors in multiple myeloma.

Papanikolaou X, Alapat D, Rosenthal A, Stein C, Epstein J, Owens R, Yaccoby S, Johnson S, Bailey C, Heuck C, Tian E, Joiner A, van Rhee F, Khan R, Zangari M, Jethava Y, Waheed S, Davies F, Morgan G, Barlogie B.

Leukemia. 2015 Aug;29(8):1713-20. doi: 10.1038/leu.2015.65. Epub 2015 Mar 10.

4.

Genetic variant in folate homeostasis is associated with lower warfarin dose in African Americans.

Daneshjou R, Gamazon ER, Burkley B, Cavallari LH, Johnson JA, Klein TE, Limdi N, Hillenmeyer S, Percha B, Karczewski KJ, Langaee T, Patel SR, Bustamante CD, Altman RB, Perera MA.

Blood. 2014 Oct 2;124(14):2298-305. doi: 10.1182/blood-2014-04-568436. Epub 2014 Jul 30.

5.

Mercaptopurine/Methotrexate maintenance therapy of childhood acute lymphoblastic leukemia: clinical facts and fiction.

Schmiegelow K, Nielsen SN, Frandsen TL, Nersting J.

J Pediatr Hematol Oncol. 2014 Oct;36(7):503-17. doi: 10.1097/MPH.0000000000000206. Review.

6.

FPGS rs1544105 polymorphism is associated with treatment outcome in pediatric B-cell precursor acute lymphoblastic leukemia.

Liu SG, Gao C, Zhang RD, Jiao Y, Cui L, Li WJ, Chen ZP, Wu MY, Zheng HY, Zhao XX, Yue ZX, Li ZG.

Cancer Cell Int. 2013 Oct 29;13(1):107. doi: 10.1186/1475-2867-13-107.

7.

Mathematical modeling of folate metabolism.

Panetta JC, Paugh SW, Evans WE.

Wiley Interdiscip Rev Syst Biol Med. 2013 Sep-Oct;5(5):603-13. doi: 10.1002/wsbm.1227. Epub 2013 May 22.

8.

A health-care system perspective on implementing genomic medicine: pediatric acute lymphoblastic leukemia as a paradigm.

Evans WE, Crews KR, Pui CH.

Clin Pharmacol Ther. 2013 Aug;94(2):224-9. doi: 10.1038/clpt.2013.9. Epub 2013 Jan 17. Review.

9.

Gene-expression signatures differ between different clinical forms of familial hemophagocytic lymphohistiocytosis.

Sumegi J, Nestheide SV, Barnes MG, Villanueva J, Zhang K, Grom AA, Filipovich AH.

Blood. 2013 Feb 14;121(7):e14-24. doi: 10.1182/blood-2012-05-425769. Epub 2012 Dec 20.

10.

Molecular diagnostics, targeted therapy, and the indication for allogeneic stem cell transplantation in acute lymphoblastic leukemia.

Oyekunle A, Haferlach T, Kröger N, Klyuchnikov E, Zander AR, Schnittger S, Bacher U.

Adv Hematol. 2011;2011:154745. doi: 10.1155/2011/154745. Epub 2011 Nov 10.

11.

Shortening infusion time for high-dose methotrexate alters antileukemic effects: a randomized prospective clinical trial.

Mikkelsen TS, Sparreboom A, Cheng C, Zhou Y, Boyett JM, Raimondi SC, Panetta JC, Bowman WP, Sandlund JT, Pui CH, Relling MV, Evans WE.

J Clin Oncol. 2011 May 1;29(13):1771-8. doi: 10.1200/JCO.2010.32.5340. Epub 2011 Mar 28.

12.

PharmGKB summary: methotrexate pathway.

Mikkelsen TS, Thorn CF, Yang JJ, Ulrich CM, French D, Zaza G, Dunnenberger HM, Marsh S, McLeod HL, Giacomini K, Becker ML, Gaedigk R, Leeder JS, Kager L, Relling MV, Evans W, Klein TE, Altman RB.

Pharmacogenet Genomics. 2011 Oct;21(10):679-86. doi: 10.1097/FPC.0b013e328343dd93. No abstract available.

13.

Improved prognosis for older adolescents with acute lymphoblastic leukemia.

Pui CH, Pei D, Campana D, Bowman WP, Sandlund JT, Kaste SC, Ribeiro RC, Rubnitz JE, Coustan-Smith E, Jeha S, Cheng C, Metzger ML, Bhojwani D, Inaba H, Raimondi SC, Onciu M, Howard SC, Leung W, Downing JR, Evans WE, Relling MV.

J Clin Oncol. 2011 Feb 1;29(4):386-91. doi: 10.1200/JCO.2010.32.0325. Epub 2010 Dec 20.

14.

Modeling mechanisms of in vivo variability in methotrexate accumulation and folate pathway inhibition in acute lymphoblastic leukemia cells.

Panetta JC, Sparreboom A, Pui CH, Relling MV, Evans WE.

PLoS Comput Biol. 2010 Dec 2;6(12):e1001019. doi: 10.1371/journal.pcbi.1001019.

15.

Pharmacogenomics in pediatric leukemia.

Paugh SW, Stocco G, Evans WE.

Curr Opin Pediatr. 2010 Dec;22(6):703-10. doi: 10.1097/MOP.0b013e32833fde85. Review.

16.

SLC19A1 pharmacogenomics summary.

Yee SW, Gong L, Badagnani I, Giacomini KM, Klein TE, Altman RB.

Pharmacogenet Genomics. 2010 Nov;20(11):708-15. doi: 10.1097/FPC.0b013e32833eca92. No abstract available.

17.

Folylpolyglutamate synthetase gene transcription is regulated by a multiprotein complex that binds the TEL-AML1 fusion in acute lymphoblastic leukemia.

Leclerc GJ, Sanderson C, Hunger S, Devidas M, Barredo JC.

Leuk Res. 2010 Dec;34(12):1601-9. doi: 10.1016/j.leukres.2010.05.012. Epub 2010 Jun 9.

18.

Methotrexate-induced side effects are not due to differences in pharmacokinetics in children with Down syndrome and acute lymphoblastic leukemia.

Buitenkamp TD, Mathôt RA, de Haas V, Pieters R, Zwaan CM.

Haematologica. 2010 Jul;95(7):1106-13. doi: 10.3324/haematol.2009.019778. Epub 2010 Apr 23.

19.

Germline genomic variants associated with childhood acute lymphoblastic leukemia.

Treviño LR, Yang W, French D, Hunger SP, Carroll WL, Devidas M, Willman C, Neale G, Downing J, Raimondi SC, Pui CH, Evans WE, Relling MV.

Nat Genet. 2009 Sep;41(9):1001-5. doi: 10.1038/ng.432. Epub 2009 Aug 16.

20.

Gene polymorphisms in folate metabolizing enzymes in adult acute lymphoblastic leukemia: effects on methotrexate-related toxicity and survival.

Ongaro A, De Mattei M, Della Porta MG, Rigolin G, Ambrosio C, Di Raimondo F, Pellati A, Masieri FF, Caruso A, Catozzi L, Gemmati D.

Haematologica. 2009 Oct;94(10):1391-8. doi: 10.3324/haematol.2009.008326. Epub 2009 Jul 31.

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