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Proteolysis in Helicobacter pylori-Induced Gastric Cancer.

Posselt G, Crabtree JE, Wessler S.

Toxins (Basel). 2017 Apr 11;9(4). pii: E134. doi: 10.3390/toxins9040134. Review.


Overexpression of the A Disintegrin and Metalloproteinase ADAM15 is linked to a Small but Highly Aggressive Subset of Prostate Cancers.

Burdelski C, Fitzner M, Hube-Magg C, Kluth M, Heumann A, Simon R, Krech T, Clauditz T, Büscheck F, Steurer S, Wittmer C, Hinsch A, Luebke AM, Jacobsen F, Minner S, Tsourlakis MC, Beyer B, Steuber T, Thederan I, Sauter G, Izbicki J, Schlomm T, Wilczak W.

Neoplasia. 2017 Apr;19(4):279-287. doi: 10.1016/j.neo.2017.01.005. Epub 2017 Mar 8.


Platelet integrin α6β1 controls lung metastasis through direct binding to cancer cell-derived ADAM9.

Mammadova-Bach E, Zigrino P, Brucker C, Bourdon C, Freund M, De Arcangelis A, Abrams SI, Orend G, Gachet C, Mangin PH.

JCI Insight. 2016 Sep 8;1(14):e88245.


ADAM9 Expression Is Associate with Glioma Tumor Grade and Histological Type, and Acts as a Prognostic Factor in Lower-Grade Gliomas.

Fan X, Wang Y, Zhang C, Liu L, Yang S, Wang Y, Liu X, Qian Z, Fang S, Qiao H, Jiang T.

Int J Mol Sci. 2016 Aug 26;17(9). pii: E1276. doi: 10.3390/ijms17091276.


The Disintegrin and Metalloprotease ADAM12 Is Associated with TGF-β-Induced Epithelial to Mesenchymal Transition.

Ruff M, Leyme A, Le Cann F, Bonnier D, Le Seyec J, Chesnel F, Fattet L, Rimokh R, Baffet G, Théret N.

PLoS One. 2015 Sep 25;10(9):e0139179. doi: 10.1371/journal.pone.0139179. eCollection 2015.


Recombinant disintegrin domain of human ADAM9 inhibits migration and invasion of DU145 prostate tumor cells.

Martin AC, Cardoso AC, Selistre-de-Araujo HS, Cominetti MR.

Cell Adh Migr. 2015;9(4):293-9. doi: 10.4161/19336918.2014.994917. Epub 2015 Jul 25.


CXCR6 expression in non-small cell lung carcinoma supports metastatic process via modulating metalloproteinases.

Mir H, Singh R, Kloecker GH, Lillard JW Jr, Singh S.

Oncotarget. 2015 Apr 30;6(12):9985-98.


Diagnostic and prognostic value of a disintegrin and metalloproteinase-17 in patients with gliomas.

Wu B, Sha L, Wang Y, Xu W, Yu Y, Feng F, Sun C, Xia L.

Oncol Lett. 2014 Dec;8(6):2616-2620. Epub 2014 Oct 1.


The effect of disintegrin-metalloproteinase ADAM9 in gastric cancer progression.

Kim JM, Jeung HC, Rha SY, Yu EJ, Kim TS, Shin YK, Zhang X, Park KH, Park SW, Chung HC, Powis G.

Mol Cancer Ther. 2014 Dec;13(12):3074-85. doi: 10.1158/1535-7163.MCT-13-1001. Epub 2014 Oct 24.


Aberrant ADAM10 expression correlates with osteosarcoma progression.

Zhao R, Ni D, Tian Y, Ni B, Wang A.

Eur J Med Res. 2014 Feb 18;19:9. doi: 10.1186/2047-783X-19-9.


ADAM-12 as a diagnostic marker for the proliferation, migration and invasion in patients with small cell lung cancer.

Shao S, Li Z, Gao W, Yu G, Liu D, Pan F.

PLoS One. 2014 Jan 21;9(1):e85936. doi: 10.1371/journal.pone.0085936. eCollection 2014.


MicroRNA-149 inhibits proliferation and cell cycle progression through the targeting of ZBTB2 in human gastric cancer.

Wang Y, Zheng X, Zhang Z, Zhou J, Zhao G, Yang J, Xia L, Wang R, Cai X, Hu H, Zhu C, Nie Y, Wu K, Zhang D, Fan D.

PLoS One. 2012;7(10):e41693. doi: 10.1371/journal.pone.0041693. Epub 2012 Oct 29.


mRNA profiling of the cancer degradome in oesophago-gastric adenocarcinoma.

Baren JP, Stewart GD, Stokes A, Gray K, Pennington CJ, O'Neill R, Deans DA, Paterson-Brown S, Riddick AC, Edwards DR, Fearon KC, Ross JA, Skipworth RJ.

Br J Cancer. 2012 Jun 26;107(1):143-9. doi: 10.1038/bjc.2012.239. Epub 2012 Jun 7.


A positive feedback loop between HER2 and ADAM12 in human head and neck cancer cells increases migration and invasion.

Rao VH, Kandel A, Lynch D, Pena Z, Marwaha N, Deng C, Watson P, Hansen LA.

Oncogene. 2012 Jun 7;31(23):2888-98. doi: 10.1038/onc.2011.460. Epub 2011 Oct 10.


ADAM12 produced by tumor cells rather than stromal cells accelerates breast tumor progression.

Fröhlich C, Nehammer C, Albrechtsen R, Kronqvist P, Kveiborg M, Sehara-Fujisawa A, Mercurio AM, Wewer UM.

Mol Cancer Res. 2011 Nov;9(11):1449-61. doi: 10.1158/1541-7786.MCR-11-0100. Epub 2011 Aug 29.


ADAM12 transmembrane and secreted isoforms promote breast tumor growth: a distinct role for ADAM12-S protein in tumor metastasis.

Roy R, Rodig S, Bielenberg D, Zurakowski D, Moses MA.

J Biol Chem. 2011 Jun 10;286(23):20758-68. doi: 10.1074/jbc.M110.216036. Epub 2011 Apr 14.


ADAM12 induces estrogen-independence in breast cancer cells.

Roy R, Moses MA.

Breast Cancer Res Treat. 2012 Feb;131(3):731-41. doi: 10.1007/s10549-011-1431-4. Epub 2011 Mar 9.


ADAM and ADAMTS gene expression in native and wound healing human lens epithelial cells.

Hodgkinson LM, Wang L, Duncan G, Edwards DR, Wormstone IM.

Mol Vis. 2010 Dec 15;16:2765-76.

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