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Effect of dihydroarteminin combined with siRNA targeting Notch1 on Notch1/c-Myc signaling in T-cell lymphoma cells.

Huo L, Wei W, Wu S, Zhao X, Zhao C, Zhao H, Sun L.

Exp Ther Med. 2018 Mar;15(3):3059-3065. doi: 10.3892/etm.2018.5784. Epub 2018 Jan 23.


Pluripotency transcription factors and Metabolic reprogramming of mitochondria in tumor-initiating stem-like cells.

Machida K.

Antioxid Redox Signal. 2017 Dec 19. doi: 10.1089/ars.2017.7241. [Epub ahead of print]


Clinical and experimental aspects of notch receptor signaling: Hajdu-Cheney syndrome and related disorders.

Canalis E.

Metabolism. 2018 Mar;80:48-56. doi: 10.1016/j.metabol.2017.08.002. Epub 2017 Aug 24.


C-terminal deletion of NOTCH1 intracellular domain (N1ICD) increases its stability but does not amplify and recapitulate N1ICD-dependent signalling.

Blain J, Bédard J, Thompson M, Boisvert FM, Boucher MJ.

Sci Rep. 2017 Jul 11;7(1):5034. doi: 10.1038/s41598-017-05119-0.


Limiting Thymic Precursor Supply Increases the Risk of Lymphoid Malignancy in Murine X-Linked Severe Combined Immunodeficiency.

Ginn SL, Hallwirth CV, Liao SH, Teber ET, Arthur JW, Wu J, Lee HC, Tay SS, Hu M, Reddel RR, McCormack MP, Thrasher AJ, Cavazzana M, Alexander SI, Alexander IE.

Mol Ther Nucleic Acids. 2017 Mar 17;6:1-14. doi: 10.1016/j.omtn.2016.11.011. Epub 2016 Dec 10.


Notch Signaling and the Skeleton.

Zanotti S, Canalis E.

Endocr Rev. 2016 Jun;37(3):223-53. doi: 10.1210/er.2016-1002. Epub 2016 Apr 13. Review.


A Phase 1 study of the novel gamma-secretase inhibitor PF-03084014 in patients with T-cell acute lymphoblastic leukemia and T-cell lymphoblastic lymphoma.

Papayannidis C, DeAngelo DJ, Stock W, Huang B, Shaik MN, Cesari R, Zheng X, Reynolds JM, English PA, Ozeck M, Aster JC, Kuo F, Huang D, Lira PD, McLachlan KR, Kern KA, Garcia-Manero G, Martinelli G.

Blood Cancer J. 2015 Sep 25;5:e350. doi: 10.1038/bcj.2015.80. No abstract available.


Notch and hedgehog signaling cooperate to maintain self-renewal of human embryonic stem cells exposed to low oxygen concentration.

Weli SC, Fink T, Cetinkaya C, Prasad MS, Pennisi CP, Zachar V.

Int J Stem Cells. 2010 May;3(2):129-37.


Notch and PKC are involved in formation of the lateral region of the dorso-ventral axis in Drosophila embryos.

Tremmel DM, Resad S, Little CJ, Wesley CS.

PLoS One. 2013 Jul 4;8(7):e67789. doi: 10.1371/journal.pone.0067789. Print 2013.


γ-Secretase inhibitors and modulators.

Golde TE, Koo EH, Felsenstein KM, Osborne BA, Miele L.

Biochim Biophys Acta. 2013 Dec;1828(12):2898-907. doi: 10.1016/j.bbamem.2013.06.005. Epub 2013 Jun 17. Review.


Cancer genome landscapes.

Vogelstein B, Papadopoulos N, Velculescu VE, Zhou S, Diaz LA Jr, Kinzler KW.

Science. 2013 Mar 29;339(6127):1546-58. doi: 10.1126/science.1235122. Review.


MicroRNAs and Glucocorticoid-Induced Apoptosis in Lymphoid Malignancies.

Sionov RV.

ISRN Hematol. 2013;2013:348212. doi: 10.1155/2013/348212. Epub 2013 Jan 29.


Presenilins and γ-secretase: structure, function, and role in Alzheimer Disease.

De Strooper B, Iwatsubo T, Wolfe MS.

Cold Spring Harb Perspect Med. 2012 Jan;2(1):a006304. doi: 10.1101/cshperspect.a006304. Review.


An overview of notch signaling in adult tissue renewal and maintenance.

Sato C, Zhao G, Ilagan MX.

Curr Alzheimer Res. 2012 Feb;9(2):227-40. Review.


Hes1 expression and CYLD repression are essential events downstream of Notch1 in T-cell leukemia.

D'Altri T, Gonzalez J, Aifantis I, Espinosa L, Bigas A.

Cell Cycle. 2011 Apr 1;10(7):1031-6. Epub 2011 Apr 1.


T-lymphoblastic lymphoma cells express high levels of BCL2, S1P1, and ICAM1, leading to a blockade of tumor cell intravasation.

Feng H, Stachura DL, White RM, Gutierrez A, Zhang L, Sanda T, Jette CA, Testa JR, Neuberg DS, Langenau DM, Kutok JL, Zon LI, Traver D, Fleming MD, Kanki JP, Look AT.

Cancer Cell. 2010 Oct 19;18(4):353-66. doi: 10.1016/j.ccr.2010.09.009.


Modeling T-cell acute lymphoblastic leukemia induced by the SCL and LMO1 oncogenes.

Tremblay M, Tremblay CS, Herblot S, Aplan PD, Hébert J, Perreault C, Hoang T.

Genes Dev. 2010 Jun 1;24(11):1093-105. doi: 10.1101/gad.1897910.


Notch target gene deregulation and maintenance of the leukemogenic phenotype do not require RBP-J kappa in Ikaros null mice.

Chari S, Umetsu SE, Winandy S.

J Immunol. 2010 Jul 1;185(1):410-7. doi: 10.4049/jimmunol.0903688. Epub 2010 May 28.


Glycogen synthase kinase-3 plays a central role in mediating glucocorticoid-induced apoptosis.

Spokoini R, Kfir-Erenfeld S, Yefenof E, Sionov RV.

Mol Endocrinol. 2010 Jun;24(6):1136-50. doi: 10.1210/me.2009-0466. Epub 2010 Apr 6.

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