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Items: 1 to 20 of 63

1.

Acute stress enhances heterodimerization and binding of corticosteroid receptors at glucocorticoid target genes in the hippocampus.

Mifsud KR, Reul JM.

Proc Natl Acad Sci U S A. 2016 Oct 4;113(40):11336-11341. Epub 2016 Sep 21.

2.

The FKBP5 Gene Affects Alcohol Drinking in Knockout Mice and Is Implicated in Alcohol Drinking in Humans.

Qiu B, Luczak SE, Wall TL, Kirchhoff AM, Xu Y, Eng MY, Stewart RB, Shou W, Boehm SL, Chester JA, Yong W, Liang T.

Int J Mol Sci. 2016 Aug 5;17(8). pii: E1271. doi: 10.3390/ijms17081271.

3.

The stress regulator FKBP51 drives chronic pain by modulating spinal glucocorticoid signaling.

Maiarù M, Tochiki KK, Cox MB, Annan LV, Bell CG, Feng X, Hausch F, Géranton SM.

Sci Transl Med. 2016 Feb 10;8(325):325ra19. doi: 10.1126/scitranslmed.aab3376.

4.

Differential Regulation of Progesterone Receptor-Mediated Transcription by CDK2 and DNA-PK.

Treviño LS, Bolt MJ, Grimm SL, Edwards DP, Mancini MA, Weigel NL.

Mol Endocrinol. 2016 Feb;30(2):158-72. doi: 10.1210/me.2015-1144. Epub 2015 Dec 11.

5.

Early-Life Adversity Interacts with FKBP5 Genotypes: Altered Working Memory and Cardiac Stress Reactivity in the Oklahoma Family Health Patterns Project.

Lovallo WR, Enoch MA, Acheson A, Cohoon AJ, Sorocco KH, Hodgkinson CA, Vincent AS, Goldman D.

Neuropsychopharmacology. 2016 Jun;41(7):1724-32. doi: 10.1038/npp.2015.347. Epub 2015 Dec 3.

6.

Adipogenesis is under surveillance of Hsp90 and the high molecular weight Immunophilin FKBP51.

Toneatto J, Charó NL, Galigniana NM, Piwien-Pilipuk G.

Adipocyte. 2015 May 13;4(4):239-47. doi: 10.1080/21623945.2015.1049401. eCollection 2015 Oct-Dec. Review.

7.

Progestins Upregulate FKBP51 Expression in Human Endometrial Stromal Cells to Induce Functional Progesterone and Glucocorticoid Withdrawal: Implications for Contraceptive- Associated Abnormal Uterine Bleeding.

Guzeloglu Kayisli O, Kayisli UA, Basar M, Semerci N, Schatz F, Lockwood CJ.

PLoS One. 2015 Oct 5;10(10):e0137855. doi: 10.1371/journal.pone.0137855. eCollection 2015.

8.

Variable telomere length across post-mortem human brain regions and specific reduction in the hippocampus of major depressive disorder.

Mamdani F, Rollins B, Morgan L, Myers RM, Barchas JD, Schatzberg AF, Watson SJ, Akil H, Potkin SG, Bunney WE, Vawter MP, Sequeira PA.

Transl Psychiatry. 2015 Sep 15;5:e636. doi: 10.1038/tp.2015.134.

9.

Gene-Stress-Epigenetic Regulation of FKBP5: Clinical and Translational Implications.

Zannas AS, Wiechmann T, Gassen NC, Binder EB.

Neuropsychopharmacology. 2016 Jan;41(1):261-74. doi: 10.1038/npp.2015.235. Epub 2015 Aug 13. Review.

10.

Steroid Receptor-Associated Immunophilins: A Gateway to Steroid Signalling.

Ratajczak T, Cluning C, Ward BK.

Clin Biochem Rev. 2015 May;36(2):31-52. Review.

11.

Response Element Composition Governs Correlations between Binding Site Affinity and Transcription in Glucocorticoid Receptor Feed-forward Loops.

Sasse SK, Zuo Z, Kadiyala V, Zhang L, Pufall MA, Jain MK, Phang TL, Stormo GD, Gerber AN.

J Biol Chem. 2015 Aug 7;290(32):19756-69. doi: 10.1074/jbc.M115.668558. Epub 2015 Jun 18.

12.

Methylation at the CpG island shore region upregulates Nr3c1 promoter activity after early-life stress.

Bockmühl Y, Patchev AV, Madejska A, Hoffmann A, Sousa JC, Sousa N, Holsboer F, Almeida OF, Spengler D.

Epigenetics. 2015;10(3):247-57. doi: 10.1080/15592294.2015.1017199.

13.

FKBP5 variation is associated with the acute and chronic effects of nicotine.

Jensen KP, Herman AI, Morean ME, Kranzler HR, Gelernter J, Sofuoglu M.

Pharmacogenomics J. 2015 Aug;15(4):340-6. doi: 10.1038/tpj.2014.76. Epub 2014 Dec 23.

14.

Hypothalamic-pituitary-adrenal axis dysfunction and illness progression in bipolar disorder.

Fries GR, Vasconcelos-Moreno MP, Gubert C, dos Santos BT, Sartori J, Eisele B, Ferrari P, Fijtman A, Rüegg J, Gassen NC, Kapczinski F, Rein T, Kauer-Sant'Anna M.

Int J Neuropsychopharmacol. 2014 Oct 31;18(1). pii: pyu043. doi: 10.1093/ijnp/pyu043.

15.

Association of FKBP51 with priming of autophagy pathways and mediation of antidepressant treatment response: evidence in cells, mice, and humans.

Gassen NC, Hartmann J, Zschocke J, Stepan J, Hafner K, Zellner A, Kirmeier T, Kollmannsberger L, Wagner KV, Dedic N, Balsevich G, Deussing JM, Kloiber S, Lucae S, Holsboer F, Eder M, Uhr M, Ising M, Schmidt MV, Rein T.

PLoS Med. 2014 Nov 11;11(11):e1001755. doi: 10.1371/journal.pmed.1001755. eCollection 2014 Nov.

16.

Cyclin A2 and its associated kinase activity are required for optimal induction of progesterone receptor target genes in breast cancer cells.

Moore NL, Edwards DP, Weigel NL.

J Steroid Biochem Mol Biol. 2014 Oct;144 Pt B:471-82. doi: 10.1016/j.jsbmb.2014.09.009. Epub 2014 Sep 16.

17.

The role of FKBP5 genotype in moderating long-term effectiveness of exposure-based psychotherapy for posttraumatic stress disorder.

Wilker S, Pfeiffer A, Kolassa S, Elbert T, Lingenfelder B, Ovuga E, Papassotiropoulos A, de Quervain D, Kolassa IT.

Transl Psychiatry. 2014 Jun 24;4:e403. doi: 10.1038/tp.2014.49.

18.

FKBP51 reciprocally regulates GRα and PPARγ activation via the Akt-p38 pathway.

Stechschulte LA, Hinds TD Jr, Ghanem SS, Shou W, Najjar SM, Sanchez ER.

Mol Endocrinol. 2014 Aug;28(8):1254-64. doi: 10.1210/me.2014-1023. Epub 2014 Jun 16.

19.

FKBP51 controls cellular adipogenesis through p38 kinase-mediated phosphorylation of GRα and PPARγ.

Stechschulte LA, Hinds TD Jr, Khuder SS, Shou W, Najjar SM, Sanchez ER.

Mol Endocrinol. 2014 Aug;28(8):1265-75. doi: 10.1210/me.2014-1022. Epub 2014 Jun 16.

20.

Multiple mineralocorticoid response elements localized in different introns regulate intermediate conductance K+ (Kcnn4) channel expression in the rat distal colon.

O'Hara B, Alvarez de la Rosa D, Rajendran VM.

PLoS One. 2014 Jun 5;9(6):e98695. doi: 10.1371/journal.pone.0098695. eCollection 2014.

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