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Items: 1 to 20 of 41


Dual-Targeting Nanoparticles for In Vivo Delivery of Suicide Genes to Chemotherapy-Resistant Ovarian Cancer Cells.

Cocco E, Deng Y, Shapiro EM, Bortolomai I, Lopez S, Lin K, Bellone S, Cui J, Menderes G, Black JD, Schwab CL, Bonazzoli E, Yang F, Predolini F, Zammataro L, Altwerger G, de Haydu C, Clark M, Alvarenga J, Ratner E, Azodi M, Silasi DA, Schwartz PE, Litkouhi B, Saltzman WM, Santin AD.

Mol Cancer Ther. 2017 Feb;16(2):323-333. doi: 10.1158/1535-7163.MCT-16-0501. Epub 2016 Dec 12.


Non-metallic nanomaterials in cancer theranostics: a review of silica- and carbon-based drug delivery systems.

Chen YC, Huang XC, Luo YL, Chang YC, Hsieh YZ, Hsu HY.

Sci Technol Adv Mater. 2013 Aug 16;14(4):044407. eCollection 2013 Aug 16. Review.


Poly-beta-amino-esters nano-vehicles based drug delivery system for cartilage.

Perni S, Prokopovich P.

Nanomedicine. 2017 Feb;13(2):539-548. doi: 10.1016/j.nano.2016.10.001. Epub 2016 Oct 13.


The transition from linear to highly branched poly(β-amino ester)s: Branching matters for gene delivery.

Zhou D, Cutlar L, Gao Y, Wang W, O'Keeffe-Ahern J, McMahon S, Duarte B, Larcher F, Rodriguez BJ, Greiser U, Wang W.

Sci Adv. 2016 Jun 17;2(6):e1600102. doi: 10.1126/sciadv.1600102. eCollection 2016 Jun 17.


Non-viral nucleic acid containing nanoparticles as cancer therapeutics.

Kozielski KL, Rui Y, Green JJ.

Expert Opin Drug Deliv. 2016 Oct;13(10):1475-87. doi: 10.1080/17425247.2016.1190707. Epub 2016 Jun 6.


Logical Analysis of Data in Structure-Activity Investigation of Polymeric Gene Delivery.

Gubskaya AV, Bonates TO, Kholodovych V, Hammer P, Welsh WJ, Langer R, Kohn J.

Macromol Theory Simul. 2011 May 23;20(4):275-285.


Biosafe nanoscale pharmaceutical adjuvant materials.

Jin S, Li S, Wang C, Liu J, Yang X, Wang PC, Zhang X, Liang XJ.

J Biomed Nanotechnol. 2014 Sep;10(9):2393-419. Review.


Small Molecule End Group of Linear Polymer Determines Cell-type Gene Delivery Efficacy.

Sunshine J, Green JJ, Mahon KP, Yang F, Eltoukhy AA, Nguyen DN, Langer R, Anderson DG.

Adv Mater. 2009 Dec 28;21(48):4947-4951. No abstract available.


Niemann-Pick C1 affects the gene delivery efficacy of degradable polymeric nanoparticles.

Eltoukhy AA, Sahay G, Cunningham JM, Anderson DG.

ACS Nano. 2014 Aug 26;8(8):7905-13. doi: 10.1021/nn501630h. Epub 2014 Jul 16.


Trigger-responsive, fast-degradable poly(β-amino ester)s for enhanced DNA unpackaging and reduced toxicity.

Deng X, Zheng N, Song Z, Yin L, Cheng J.

Biomaterials. 2014 Jun;35(18):5006-15. doi: 10.1016/j.biomaterials.2014.03.005. Epub 2014 Mar 24.


Development of poly(β-amino ester)-based biodegradable nanoparticles for nonviral delivery of minicircle DNA.

Keeney M, Ong SG, Padilla A, Yao Z, Goodman S, Wu JC, Yang F.

ACS Nano. 2013 Aug 27;7(8):7241-50. doi: 10.1021/nn402657d. Epub 2013 Jul 16.


Degradable terpolymers with alkyl side chains demonstrate enhanced gene delivery potency and nanoparticle stability.

Eltoukhy AA, Chen D, Alabi CA, Langer R, Anderson DG.

Adv Mater. 2013 Mar 13;25(10):1487-93. doi: 10.1002/adma.201204346. Epub 2013 Jan 4.


Facile functionalization of polyesters through thiol-yne chemistry for the design of degradable, cell-penetrating and gene delivery dual-functional agents.

Zhang Z, Yin L, Xu Y, Tong R, Lu Y, Ren J, Cheng J.

Biomacromolecules. 2012 Nov 12;13(11):3456-62. doi: 10.1021/bm301333w. Epub 2012 Oct 26.


Advances in polymeric and inorganic vectors for nonviral nucleic acid delivery.

Sunshine JC, Bishop CJ, Green JJ.

Ther Deliv. 2011 Apr;2(4):493-521. Review.


Effect of molecular weight of amine end-modified poly(β-amino ester)s on gene delivery efficiency and toxicity.

Eltoukhy AA, Siegwart DJ, Alabi CA, Rajan JS, Langer R, Anderson DG.

Biomaterials. 2012 May;33(13):3594-603. doi: 10.1016/j.biomaterials.2012.01.046. Epub 2012 Feb 14.


Transfecting the hard-to-transfect lymphoma/leukemia cells using a simple cationic polymer nanocomplex.

Zhao N, Qi J, Zeng Z, Parekh P, Chang CC, Tung CH, Zu Y.

J Control Release. 2012 Apr 10;159(1):104-10. doi: 10.1016/j.jconrel.2012.01.007. Epub 2012 Jan 15.


Toxin-based therapeutic approaches.

Shapira A, Benhar I.

Toxins (Basel). 2010 Nov;2(11):2519-83. doi: 10.3390/toxins2112519. Epub 2010 Oct 28. Review.


Rad51 promoter-targeted gene therapy is effective for in vivo visualization and treatment of cancer.

Hine CM, Seluanov A, Gorbunova V.

Mol Ther. 2012 Feb;20(2):347-55. doi: 10.1038/mt.2011.215. Epub 2011 Oct 18.


Discovery of cationic polymers for non-viral gene delivery using combinatorial approaches.

Barua S, Ramos J, Potta T, Taylor D, Huang HC, Montanez G, Rege K.

Comb Chem High Throughput Screen. 2011 Dec;14(10):908-24. Review.


Combinatorial synthesis of chemically diverse core-shell nanoparticles for intracellular delivery.

Siegwart DJ, Whitehead KA, Nuhn L, Sahay G, Cheng H, Jiang S, Ma M, Lytton-Jean A, Vegas A, Fenton P, Levins CG, Love KT, Lee H, Cortez C, Collins SP, Li YF, Jang J, Querbes W, Zurenko C, Novobrantseva T, Langer R, Anderson DG.

Proc Natl Acad Sci U S A. 2011 Aug 9;108(32):12996-3001. doi: 10.1073/pnas.1106379108. Epub 2011 Jul 22.

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