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Items: 1 to 20 of 33


Convergence of hepcidin deficiency, systemic iron overloading, heme accumulation, and REV-ERBα/β activation in aryl hydrocarbon receptor-elicited hepatotoxicity.

Fader KA, Nault R, Kirby MP, Markous G, Matthews J, Zacharewski TR.

Toxicol Appl Pharmacol. 2017 Apr 15;321:1-17. doi: 10.1016/j.taap.2017.02.006. Epub 2017 Feb 16.


Loss of Hif-2α Rescues the Hif-1α Deletion Phenotype of Neonatal Respiratory Distress In Mice.

Saini Y, Proper SP, Dornbos P, Greenwood KK, Kopec AK, Lynn SG, Grier E, Burgoon LD, Zacharewski TR, Thomas RS, Harkema JR, LaPres JJ.

PLoS One. 2015 Sep 30;10(9):e0139270. doi: 10.1371/journal.pone.0139270. eCollection 2015.


2,3,7,8-Tetrachlorodibenzo-p-Dioxin Alters Lipid Metabolism and Depletes Immune Cell Populations in the Jejunum of C57BL/6 Mice.

Fader KA, Nault R, Ammendolia DA, Harkema JR, Williams KJ, Crawford RB, Kaminski NE, Potter D, Sharratt B, Zacharewski TR.

Toxicol Sci. 2015 Dec;148(2):567-80. doi: 10.1093/toxsci/kfv206. Epub 2015 Sep 16.


MiR-320e is a novel prognostic biomarker in colorectal cancer.

Perez-Carbonell L, Sinicrope FA, Alberts SR, Oberg AL, Balaguer F, Castells A, Boland CR, Goel A.

Br J Cancer. 2015 Jun 30;113(1):83-90. doi: 10.1038/bjc.2015.168. Epub 2015 Jun 2.


RNA-Seq versus oligonucleotide array assessment of dose-dependent TCDD-elicited hepatic gene expression in mice.

Nault R, Fader KA, Zacharewski T.

BMC Genomics. 2015 May 10;16:373. doi: 10.1186/s12864-015-1527-z.


Loss of HSulf-1 promotes altered lipid metabolism in ovarian cancer.

Roy D, Mondal S, Wang C, He X, Khurana A, Giri S, Hoffmann R, Jung DB, Kim SH, Chini EN, Periera JC, Folmes CD, Mariani A, Dowdy SC, Bakkum-Gamez JN, Riska SM, Oberg AL, Karoly ED, Bell LN, Chien J, Shridhar V.

Cancer Metab. 2014 Aug 18;2:13. doi: 10.1186/2049-3002-2-13. eCollection 2014. Erratum in: Cancer Metab. 2014;2:24.


Comparisons of differential gene expression elicited by TCDD, PCB126, βNF, or ICZ in mouse hepatoma Hepa1c1c7 cells and C57BL/6 mouse liver.

Nault R, Forgacs AL, Dere E, Zacharewski TR.

Toxicol Lett. 2013 Oct 23;223(1):52-9. doi: 10.1016/j.toxlet.2013.08.013. Epub 2013 Aug 29.


Toxicogenomic evaluation of long-term hepatic effects of TCDD in immature, ovariectomized C57BL/6 mice.

Kopec AK, Boverhof DR, Nault R, Harkema JR, Tashiro C, Potter D, Sharratt B, Chittim B, Zacharewski TR.

Toxicol Sci. 2013 Oct;135(2):465-75. doi: 10.1093/toxsci/kft156. Epub 2013 Jul 17.


Comparative analysis of temporal and dose-dependent TCDD-elicited gene expression in human, mouse, and rat primary hepatocytes.

Forgacs AL, Dere E, Angrish MM, Zacharewski TR.

Toxicol Sci. 2013 May;133(1):54-66. doi: 10.1093/toxsci/kft028. Epub 2013 Feb 15.


Comparison of TCDD-elicited genome-wide hepatic gene expression in Sprague-Dawley rats and C57BL/6 mice.

Nault R, Kim S, Zacharewski TR.

Toxicol Appl Pharmacol. 2013 Mar 1;267(2):184-91. doi: 10.1016/j.taap.2012.11.028. Epub 2012 Dec 11.


Statistical methods for quantitative mass spectrometry proteomic experiments with labeling.

Oberg AL, Mahoney DW.

BMC Bioinformatics. 2012;13 Suppl 16:S7. doi: 10.1186/1471-2105-13-S16-S7. Epub 2012 Nov 5. Review.


MIPHENO: data normalization for high throughput metabolite analysis.

Bell SM, Burgoon LD, Last RL.

BMC Bioinformatics. 2012 Jan 13;13:10. doi: 10.1186/1471-2105-13-10.


Non-additive hepatic gene expression elicited by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) and 2,2',4,4',5,5'-hexachlorobiphenyl (PCB153) co-treatment in C57BL/6 mice.

Kopec AK, D'Souza ML, Mets BD, Burgoon LD, Reese SE, Archer KJ, Potter D, Tashiro C, Sharratt B, Harkema JR, Zacharewski TR.

Toxicol Appl Pharmacol. 2011 Oct 15;256(2):154-67. doi: 10.1016/j.taap.2011.08.002. Epub 2011 Aug 7.


Relative quantification: characterization of bias, variability and fold changes in mass spectrometry data from iTRAQ-labeled peptides.

Mahoney DW, Therneau TM, Heppelmann CJ, Higgins L, Benson LM, Zenka RM, Jagtap P, Nelsestuen GL, Bergen HR, Oberg AL.

J Proteome Res. 2011 Sep 2;10(9):4325-33. doi: 10.1021/pr2001308. Epub 2011 Aug 2.


miRNA expression in colon polyps provides evidence for a multihit model of colon cancer.

Oberg AL, French AJ, Sarver AL, Subramanian S, Morlan BW, Riska SM, Borralho PM, Cunningham JM, Boardman LA, Wang L, Smyrk TC, Asmann Y, Steer CJ, Thibodeau SN.

PLoS One. 2011;6(6):e20465. doi: 10.1371/journal.pone.0020465. Epub 2011 Jun 9.


Differences in TCDD-elicited gene expression profiles in human HepG2, mouse Hepa1c1c7 and rat H4IIE hepatoma cells.

Dere E, Lee AW, Burgoon LD, Zacharewski TR.

BMC Genomics. 2011 Apr 15;12:193. doi: 10.1186/1471-2164-12-193.


Genome-wide computational analysis of dioxin response element location and distribution in the human, mouse, and rat genomes.

Dere E, Forgacs AL, Zacharewski TR, Burgoon LD.

Chem Res Toxicol. 2011 Apr 18;24(4):494-504. doi: 10.1021/tx100328r. Epub 2011 Mar 17.


Optimizing high dimensional gene expression studies for immune response following smallpox vaccination using Taqman® low density immune arrays.

Oberg AL, Dhiman N, Grill DE, Ryan JE, Kennedy RB, Poland GA.

J Immunol Methods. 2011 Mar 7;366(1-2):69-78. doi: 10.1016/j.jim.2011.01.011. Epub 2011 Jan 28.


Differential gene expression in well-healed and poorly healed experimental aneurysms after coil treatment.

Kadirvel R, Ding YH, Dai D, Lewis DA, Kallmes DF.

Radiology. 2010 Nov;257(2):418-26. doi: 10.1148/radiol.10100362. Epub 2010 Sep 9.


Automated dose-response analysis and comparative toxicogenomic evaluation of the hepatic effects elicited by TCDD, TCDF, and PCB126 in C57BL/6 mice.

Kopec AK, Burgoon LD, Ibrahim-Aibo D, Burg AR, Lee AW, Tashiro C, Potter D, Sharratt B, Harkema JR, Rowlands JC, Budinsky RA, Zacharewski TR.

Toxicol Sci. 2010 Nov;118(1):286-97. doi: 10.1093/toxsci/kfq236. Epub 2010 Aug 11.

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