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Items: 1 to 20 of 155

1.

Selective induction of alternatively spliced FynT isoform by TNF facilitates persistent inflammatory responses in astrocytes.

Lee C, Low CY, Wong SY, Lai MK, Tan MG.

Sci Rep. 2017 Mar 7;7:43651. doi: 10.1038/srep43651.

2.

Intrinsic Photosensitivity Enhances Motility of T Lymphocytes.

Phan TX, Jaruga B, Pingle SC, Bandyopadhyay BC, Ahern GP.

Sci Rep. 2016 Dec 20;6:39479. doi: 10.1038/srep39479.

3.

Aurora-A shines on T cell activation through the regulation of Lck.

Blas-Rus N, Bustos-Morán E, Martín-Cófreces NB, Sánchez-Madrid F.

Bioessays. 2017 Feb;39(2). doi: 10.1002/bies.201600156.

PMID:
27910998
4.

A Pyrazolo[3,4-d]pyrimidine Compound Reduces Cell Viability and Induces Apoptosis in Different Hematological Malignancies.

Laurenzana I, Caivano A, La Rocca F, Trino S, De Luca L, D'Alessio F, Schenone S, Falco G, Botta M, Del Vecchio L, Musto P.

Front Pharmacol. 2016 Nov 7;7:416.

5.

Fyn phosphorylates AMPK to inhibit AMPK activity and AMP-dependent activation of autophagy.

Yamada E, Okada S, Bastie CC, Vatish M, Nakajima Y, Shibusawa R, Ozawa A, Pessin JE, Yamada M.

Oncotarget. 2016 Nov 15;7(46):74612-74629. doi: 10.18632/oncotarget.11916.

6.

Structural and Biochemical Basis for Intracellular Kinase Inhibition by Src-specific Peptidic Macrocycles.

Aleem SU, Georghiou G, Kleiner RE, Guja KE, Craddock BP, Lyczek A, Chan AI, Garcia-Diaz M, Miller WT, Liu DR, Seeliger MA.

Cell Chem Biol. 2016 Sep 22;23(9):1103-12. doi: 10.1016/j.chembiol.2016.07.017.

PMID:
27593110
7.

A Pyrazolo[3,4-d]pyrimidine compound inhibits Fyn phosphorylation and induces apoptosis in natural killer cell leukemia.

Laurenzana I, Caivano A, Trino S, De Luca L, La Rocca F, Simeon V, Tintori C, D'Alessio F, Teramo A, Zambello R, Traficante A, Maietti M, Semenzato G, Schenone S, Botta M, Musto P, Del Vecchio L.

Oncotarget. 2016 Oct 4;7(40):65171-65184. doi: 10.18632/oncotarget.11496.

8.

Lipids Regulate Lck Protein Activity through Their Interactions with the Lck Src Homology 2 Domain.

Sheng R, Jung DJ, Silkov A, Kim H, Singaram I, Wang ZG, Xin Y, Kim E, Park MJ, Thiagarajan-Rosenkranz P, Smrt S, Honig B, Baek K, Ryu S, Lorieau J, Kim YM, Cho W.

J Biol Chem. 2016 Aug 19;291(34):17639-50. doi: 10.1074/jbc.M116.720284.

PMID:
27334919
9.

Aurora A drives early signalling and vesicle dynamics during T-cell activation.

Blas-Rus N, Bustos-Morán E, Pérez de Castro I, de Cárcer G, Borroto A, Camafeita E, Jorge I, Vázquez J, Alarcón B, Malumbres M, Martín-Cófreces NB, Sánchez-Madrid F.

Nat Commun. 2016 Apr 19;7:11389. doi: 10.1038/ncomms11389.

10.

Novel autophosphorylation sites of Src family kinases regulate kinase activity and SH2 domain-binding capacity.

Weir ME, Mann JE, Corwin T, Fulton ZW, Hao JM, Maniscalco JF, Kenney MC, Roman Roque KM, Chapdelaine EF, Stelzl U, Deming PB, Ballif BA, Hinkle KL.

FEBS Lett. 2016 Apr;590(8):1042-52. doi: 10.1002/1873-3468.12144.

PMID:
27001024
11.

A Central Nervous System-Dependent Intron-Embedded Gene Encodes a Novel Murine Fyn Binding Protein.

Ben Khalaf N, Taha S, Bakhiet M, Fathallah MD.

PLoS One. 2016 Feb 22;11(2):e0149612. doi: 10.1371/journal.pone.0149612.

12.

The exploration of network motifs as potential drug targets from post-translational regulatory networks.

Zhang XD, Song J, Bork P, Zhao XM.

Sci Rep. 2016 Feb 8;6:20558. doi: 10.1038/srep20558.

13.

The HLA-B*35 allele modulates ER stress, inflammation and proliferation in PBMCs from Limited Cutaneous Systemic Sclerosis patients.

Lenna S, Assassi S, Farina GA, Mantero JC, Scorza R, Lafyatis R, Farber HW, Trojanowska M.

Arthritis Res Ther. 2015 Dec 16;17:363. doi: 10.1186/s13075-015-0881-1.

14.

Src Family Kinases in Brain Edema After Acute Brain Injury.

Liu D, Zhang X, Hu B, Ander BP.

Acta Neurochir Suppl. 2016;121:185-90. doi: 10.1007/978-3-319-18497-5_33.

15.

Differential expression of T cell-related genes in AMI and SA stages of coronary artery disease.

Yan W, Wang L, Jiang J, Xu W, Gong Z, Duan Q, Li C, Song H, Che L, Shen Y, Zhou L.

Int J Clin Exp Med. 2015 Jul 15;8(7):10875-84.

16.

Small molecule inhibition of Csk alters affinity recognition by T cells.

Manz BN, Tan YX, Courtney AH, Rutaganira F, Palmer E, Shokat KM, Weiss A.

Elife. 2015 Aug 24;4. doi: 10.7554/eLife.08088.

17.

Ligands Binding to Cell Surface Ganglioside GD2 Cause Src-Dependent Activation of N-Methyl-D-Aspartate Receptor Signaling and Changes in Cellular Morphology.

Tong W, Maira M, Gagnon M, Saragovi HU.

PLoS One. 2015 Aug 7;10(8):e0134255. doi: 10.1371/journal.pone.0134255.

18.
19.

Discs Large Homolog 1 Splice Variants Regulate p38-Dependent and -Independent Effector Functions in CD8+ T Cells.

Silva O, Crocetti J, Humphries LA, Burkhardt JK, Miceli MC.

PLoS One. 2015 Jul 17;10(7):e0133353. doi: 10.1371/journal.pone.0133353.

20.

Fyn Kinase Regulates Microglial Neuroinflammatory Responses in Cell Culture and Animal Models of Parkinson's Disease.

Panicker N, Saminathan H, Jin H, Neal M, Harischandra DS, Gordon R, Kanthasamy K, Lawana V, Sarkar S, Luo J, Anantharam V, Kanthasamy AG, Kanthasamy A.

J Neurosci. 2015 Jul 8;35(27):10058-77. doi: 10.1523/JNEUROSCI.0302-15.2015.

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