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The Mediator Complex Subunits MED14, MED15, and MED16 Are Involved in Defense Signaling Crosstalk in Arabidopsis.

Wang C, Du X, Mou Z.

Front Plant Sci. 2016 Dec 22;7:1947. doi: 10.3389/fpls.2016.01947. eCollection 2016.


Mediator Undergoes a Compositional Change during Transcriptional Activation.

Petrenko N, Jin Y, Wong KH, Struhl K.

Mol Cell. 2016 Nov 3;64(3):443-454. doi: 10.1016/j.molcel.2016.09.015. Epub 2016 Oct 20.


Functional interplay between Mediator and TFIIB in preinitiation complex assembly in relation to promoter architecture.

Eychenne T, Novikova E, Barrault MB, Alibert O, Boschiero C, Peixeiro N, Cornu D, Redeker V, Kuras L, Nicolas P, Werner M, Soutourina J.

Genes Dev. 2016 Sep 15;30(18):2119-2132. Epub 2016 Sep 29.


Structure of a Complete Mediator-RNA Polymerase II Pre-Initiation Complex.

Robinson PJ, Trnka MJ, Bushnell DA, Davis RE, Mattei PJ, Burlingame AL, Kornberg RD.

Cell. 2016 Sep 8;166(6):1411-1422.e16. doi: 10.1016/j.cell.2016.08.050.


An Integrated Genomic Strategy Delineates Candidate Mediator Genes Regulating Grain Size and Weight in Rice.

Malik N, Dwivedi N, Singh AK, Parida SK, Agarwal P, Thakur JK, Tyagi AK.

Sci Rep. 2016 Mar 22;6:23253. doi: 10.1038/srep23253.


Evolution of disorder in Mediator complex and its functional relevance.

Nagulapalli M, Maji S, Dwivedi N, Dahiya P, Thakur JK.

Nucleic Acids Res. 2016 Feb 29;44(4):1591-612. doi: 10.1093/nar/gkv1135. Epub 2015 Nov 20.


Arabidopsis CBP1 Is a Novel Regulator of Transcription Initiation in Central Cell-Mediated Pollen Tube Guidance.

Li HJ, Zhu SS, Zhang MX, Wang T, Liang L, Xue Y, Shi DQ, Liu J, Yang WC.

Plant Cell. 2015 Oct;27(10):2880-93. doi: 10.1105/tpc.15.00370. Epub 2015 Oct 13.


Molecular architecture of the yeast Mediator complex.

Robinson PJ, Trnka MJ, Pellarin R, Greenberg CH, Bushnell DA, Davis R, Burlingame AL, Sali A, Kornberg RD.

Elife. 2015 Sep 24;4. pii: e08719. doi: 10.7554/eLife.08719.


Mediator independently orchestrates multiple steps of preinitiation complex assembly in vivo.

Eyboulet F, Wydau-Dematteis S, Eychenne T, Alibert O, Neil H, Boschiero C, Nevers MC, Volland H, Cornu D, Redeker V, Werner M, Soutourina J.

Nucleic Acids Res. 2015 Oct 30;43(19):9214-31. doi: 10.1093/nar/gkv782. Epub 2015 Aug 3.


The Arabidopsis Mediator Complex Subunit16 Is a Key Component of Basal Resistance against the Necrotrophic Fungal Pathogen Sclerotinia sclerotiorum.

Wang C, Yao J, Du X, Zhang Y, Sun Y, Rollins JA, Mou Z.

Plant Physiol. 2015 Sep;169(1):856-72. doi: 10.1104/pp.15.00351. Epub 2015 Jul 4.


The Mediator complex: a central integrator of transcription.

Allen BL, Taatjes DJ.

Nat Rev Mol Cell Biol. 2015 Mar;16(3):155-66. doi: 10.1038/nrm3951. Epub 2015 Feb 18. Review.


The Mediator complex of Caenorhabditis elegans: insights into the developmental and physiological roles of a conserved transcriptional coregulator.

Grants JM, Goh GY, Taubert S.

Nucleic Acids Res. 2015 Feb 27;43(4):2442-53. doi: 10.1093/nar/gkv037. Epub 2015 Jan 29. Review.


Reconstitution of active human core Mediator complex reveals a critical role of the MED14 subunit.

Cevher MA, Shi Y, Li D, Chait BT, Malik S, Roeder RG.

Nat Struct Mol Biol. 2014 Dec;21(12):1028-34. doi: 10.1038/nsmb.2914. Epub 2014 Nov 10.


CYCLIN-DEPENDENT KINASE8 differentially regulates plant immunity to fungal pathogens through kinase-dependent and -independent functions in Arabidopsis.

Zhu Y, Schluttenhoffer CM, Wang P, Fu F, Thimmapuram J, Zhu JK, Lee SY, Yun DJ, Mengiste T.

Plant Cell. 2014 Oct;26(10):4149-70. doi: 10.1105/tpc.114.128611. Epub 2014 Oct 3.


Accumulation of a threonine biosynthetic intermediate attenuates general amino acid control by accelerating degradation of Gcn4 via Pho85 and Cdk8.

Rawal Y, Qiu H, Hinnebusch AG.

PLoS Genet. 2014 Jul 31;10(7):e1004534. doi: 10.1371/journal.pgen.1004534. eCollection 2014 Jul.


Pivotal role for a tail subunit of the RNA polymerase II mediator complex CgMed2 in azole tolerance and adherence in Candida glabrata.

Borah S, Shivarathri R, Srivastava VK, Ferrari S, Sanglard D, Kaur R.

Antimicrob Agents Chemother. 2014 Oct;58(10):5976-86. doi: 10.1128/AAC.02786-14. Epub 2014 Jul 28.


PHD and TFIIS-Like domains of the Bye1 transcription factor determine its multivalent genomic distribution.

Pinskaya M, Ghavi-Helm Y, Mariotte-Labarre S, Morillon A, Soutourina J, Werner M.

PLoS One. 2014 Jul 16;9(7):e102464. doi: 10.1371/journal.pone.0102464. eCollection 2014.


Redefining the modular organization of the core Mediator complex.

Wang X, Sun Q, Ding Z, Ji J, Wang J, Kong X, Yang J, Cai G.

Cell Res. 2014 Jul;24(7):796-808. doi: 10.1038/cr.2014.64. Epub 2014 May 9.


Med1 subunit of the mediator complex in nuclear receptor-regulated energy metabolism, liver regeneration, and hepatocarcinogenesis.

Jia Y, Viswakarma N, Reddy JK.

Gene Expr. 2014;16(2):63-75. doi: 10.3727/105221614X13919976902219. Review.

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