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Items: 12

1.

Postnatal and adult consequences of loss of huntingtin during development: Implications for Huntington's disease.

Arteaga-Bracho EE, Gulinello M, Winchester ML, Pichamoorthy N, Petronglo JR, Zambrano AD, Inocencio J, De Jesus CD, Louie JO, Gokhan S, Mehler MF, Molero AE.

Neurobiol Dis. 2016 Dec;96:144-155. doi: 10.1016/j.nbd.2016.09.006. Epub 2016 Sep 10.

PMID:
27623015
2.

Xyloketal-derived small molecules show protective effect by decreasing mutant Huntingtin protein aggregates in Caenorhabditis elegans model of Huntington's disease.

Zeng Y, Guo W, Xu G, Wang Q, Feng L, Long S, Liang F, Huang Y, Lu X, Li S, Zhou J, Burgunder JM, Pang J, Pei Z.

Drug Des Devel Ther. 2016 Apr 13;10:1443-51. doi: 10.2147/DDDT.S94666. eCollection 2016.

3.

Phosphorylation of mutant huntingtin at serine 116 modulates neuronal toxicity.

Watkin EE, Arbez N, Waldron-Roby E, O'Meally R, Ratovitski T, Cole RN, Ross CA.

PLoS One. 2014 Feb 5;9(2):e88284. doi: 10.1371/journal.pone.0088284. eCollection 2014.

4.

Large Animal Models of Huntington's Disease.

Li XJ, Li S.

Curr Top Behav Neurosci. 2015;22:149-60. doi: 10.1007/7854_2013_246. Review.

5.

The role of chaperone-mediated autophagy in huntingtin degradation.

Qi L, Zhang XD, Wu JC, Lin F, Wang J, DiFiglia M, Qin ZH.

PLoS One. 2012;7(10):e46834. doi: 10.1371/journal.pone.0046834. Epub 2012 Oct 11.

6.

The Aggregation of Huntingtin and α-Synuclein.

Chánez-Cárdenas ME, Vázquez-Contreras E.

J Biophys. 2012;2012:606172. doi: 10.1155/2012/606172. Epub 2012 Jul 26.

7.

Influence of species differences on the neuropathology of transgenic Huntington's disease animal models.

Li XJ, Li S.

J Genet Genomics. 2012 Jun 20;39(6):239-45. doi: 10.1016/j.jgg.2012.05.002. Epub 2012 May 14. Review.

8.

Huntingtin aggregation kinetics and their pathological role in a Drosophila Huntington's disease model.

Weiss KR, Kimura Y, Lee WC, Littleton JT.

Genetics. 2012 Feb;190(2):581-600. doi: 10.1534/genetics.111.133710. Epub 2011 Nov 17.

9.

Perturbation with intrabodies reveals that calpain cleavage is required for degradation of huntingtin exon 1.

Southwell AL, Bugg CW, Kaltenbach LS, Dunn D, Butland S, Weiss A, Paganetti P, Lo DC, Patterson PH.

PLoS One. 2011 Jan 31;6(1):e16676. doi: 10.1371/journal.pone.0016676.

10.

Control of intracellular calcium signaling as a neuroprotective strategy.

Duncan RS, Goad DL, Grillo MA, Kaja S, Payne AJ, Koulen P.

Molecules. 2010 Mar 3;15(3):1168-95. doi: 10.3390/molecules15031168. Review.

11.

Polyglutamine toxicity in non-neuronal cells.

Bradford JW, Li S, Li XJ.

Cell Res. 2010 Apr;20(4):400-7. doi: 10.1038/cr.2010.32. Epub 2010 Mar 16. Review.

12.

Autophagy induced by Alexander disease-mutant GFAP accumulation is regulated by p38/MAPK and mTOR signaling pathways.

Tang G, Yue Z, Talloczy Z, Hagemann T, Cho W, Messing A, Sulzer DL, Goldman JE.

Hum Mol Genet. 2008 Jun 1;17(11):1540-55. doi: 10.1093/hmg/ddn042. Epub 2008 Feb 14.

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