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Items: 1 to 20 of 195

1.

RIT1 controls actin dynamics via complex formation with RAC1/CDC42 and PAK1.

Meyer Zum B├╝schenfelde U, Brandenstein LI, von Elsner L, Flato K, Holling T, Zenker M, Rosenberger G, Kutsche K.

PLoS Genet. 2018 May 7;14(5):e1007370. doi: 10.1371/journal.pgen.1007370. eCollection 2018 May.

2.

Complement Receptor 3-Mediated Inhibition of Inflammasome Priming by Ras GTPase-Activating Protein During Francisella tularensis Phagocytosis by Human Mononuclear Phagocytes.

Hoang KV, Rajaram MVS, Curry HM, Gavrilin MA, Wewers MD, Schlesinger LS.

Front Immunol. 2018 Mar 26;9:561. doi: 10.3389/fimmu.2018.00561. eCollection 2018.

3.

Physiological genomics identifies genetic modifiers of long QT syndrome type 2 severity.

Chai S, Wan X, Ramirez-Navarro A, Tesar PJ, Kaufman ES, Ficker E, George AL Jr., Deschênes I.

J Clin Invest. 2018 Mar 1;128(3):1043-1056. doi: 10.1172/JCI94996. Epub 2018 Feb 12.

4.

Recurrent De Novo Mutations Disturbing the GTP/GDP Binding Pocket of RAB11B Cause Intellectual Disability and a Distinctive Brain Phenotype.

Lamers IJC, Reijnders MRF, Venselaar H, Kraus A; DDD Study, Jansen S, de Vries BBA, Houge G, Gradek GA, Seo J, Choi M, Chae JH, van der Burgt I, Pfundt R, Letteboer SJF, van Beersum SEC, Dusseljee S, Brunner HG, Doherty D, Kleefstra T, Roepman R.

Am J Hum Genet. 2017 Nov 2;101(5):824-832. doi: 10.1016/j.ajhg.2017.09.015. Epub 2017 Oct 26.

5.

Rab GTPases in cilium formation and function.

Blacque OE, Scheidel N, Kuhns S.

Small GTPases. 2018 Mar 4;9(1-2):76-94. doi: 10.1080/21541248.2017.1353847. Epub 2017 Oct 26.

6.

Regulation of NOTCH signaling by RAB7 and RAB8 requires carboxyl methylation by ICMT.

Court H, Ahearn IM, Amoyel M, Bach EA, Philips MR.

J Cell Biol. 2017 Dec 4;216(12):4165-4182. doi: 10.1083/jcb.201701053. Epub 2017 Oct 19.

PMID:
29051265
7.

Rab25 GTPase: Functional roles in cancer.

Wang S, Hu C, Wu F, He S.

Oncotarget. 2017 Jul 26;8(38):64591-64599. doi: 10.18632/oncotarget.19571. eCollection 2017 Sep 8. Review.

8.

Evaluation of the selectivity and sensitivity of isoform- and mutation-specific RAS antibodies.

Waters AM, Ozkan-Dagliyan I, Vaseva AV, Fer N, Strathern LA, Hobbs GA, Tessier-Cloutier B, Gillette WK, Bagni R, Whiteley GR, Hartley JL, McCormick F, Cox AD, Houghton PJ, Huntsman DG, Philips MR, Der CJ.

Sci Signal. 2017 Sep 26;10(498). pii: eaao3332. doi: 10.1126/scisignal.aao3332.

9.

RAC1 Missense Mutations in Developmental Disorders with Diverse Phenotypes.

Reijnders MRF, Ansor NM, Kousi M, Yue WW, Tan PL, Clarkson K, Clayton-Smith J, Corning K, Jones JR, Lam WWK, Mancini GMS, Marcelis C, Mohammed S, Pfundt R, Roifman M, Cohn R, Chitayat D; Deciphering Developmental Disorders Study, Millard TH, Katsanis N, Brunner HG, Banka S.

Am J Hum Genet. 2017 Sep 7;101(3):466-477. doi: 10.1016/j.ajhg.2017.08.007.

10.

Endocytosis and Enamel Formation.

Pham CD, Smith CE, Hu Y, Hu JC, Simmer JP, Chun YP.

Front Physiol. 2017 Jul 31;8:529. doi: 10.3389/fphys.2017.00529. eCollection 2017. Review.

11.

The Prenylated Rab GTPase Receptor PRA1.F4 Contributes to Protein Exit from the Golgi Apparatus.

Lee MH, Yoo YJ, Kim DH, Hanh NH, Kwon Y, Hwang I.

Plant Physiol. 2017 Jul;174(3):1576-1594. doi: 10.1104/pp.17.00466. Epub 2017 May 9.

PMID:
28487479
12.

K-RAS and N-RAS mutations in testicular germ cell tumors.

Hacioglu BM, Kodaz H, Erdogan B, Cinkaya A, Tastekin E, Hacibekiroglu I, Turkmen E, Kostek O, Genc E, Uzunoglu S, Cicin I.

Bosn J Basic Med Sci. 2017 May 20;17(2):159-163. doi: 10.17305/bjbms.2017.1764.

13.

Rab GTPases: master regulators that establish the secretory and endocytic pathways.

Pfeffer SR.

Mol Biol Cell. 2017 Mar 15;28(6):712-715. doi: 10.1091/mbc.E16-10-0737. Review.

14.

Ras-like family small GTPases genes in Nilaparvata lugens: Identification, phylogenetic analysis, gene expression and function in nymphal development.

Wang W, Li K, Wan P, Lai F, Fu Q, Zhu T.

PLoS One. 2017 Feb 27;12(2):e0172701. doi: 10.1371/journal.pone.0172701. eCollection 2017.

15.

Multivalent Small-Molecule Pan-RAS Inhibitors.

Welsch ME, Kaplan A, Chambers JM, Stokes ME, Bos PH, Zask A, Zhang Y, Sanchez-Martin M, Badgley MA, Huang CS, Tran TH, Akkiraju H, Brown LM, Nandakumar R, Cremers S, Yang WS, Tong L, Olive KP, Ferrando A, Stockwell BR.

Cell. 2017 Feb 23;168(5):878-889.e29. doi: 10.1016/j.cell.2017.02.006.

16.

Protein Interactions at Endothelial Junctions and Signaling Mechanisms Regulating Endothelial Permeability.

Komarova YA, Kruse K, Mehta D, Malik AB.

Circ Res. 2017 Jan 6;120(1):179-206. doi: 10.1161/CIRCRESAHA.116.306534. Review.

17.

RIT1 GTPase Regulates Sox2 Transcriptional Activity and Hippocampal Neurogenesis.

Mir S, Cai W, Andres DA.

J Biol Chem. 2017 Feb 10;292(6):2054-2064. doi: 10.1074/jbc.M116.749770. Epub 2016 Dec 22.

18.

A Novel HRAS Mutation Independently Contributes to Left Ventricular Hypertrophy in a Family with a Known MYH7 Mutation.

Sana ME, Quilliam LA, Spitaleri A, Pezzoli L, Marchetti D, Lodrini C, Candiago E, Lincesso AR, Ferrazzi P, Iascone M.

PLoS One. 2016 Dec 21;11(12):e0168501. doi: 10.1371/journal.pone.0168501. eCollection 2016.

19.

A Fungus-Specific Protein Domain Is Essential for RasA-Mediated Morphogenetic Signaling in Aspergillus fumigatus.

Al Abdallah Q, Norton TS, Hill AM, LeClaire LL, Fortwendel JR.

mSphere. 2016 Nov 30;1(6). pii: e00234-16. eCollection 2016 Nov-Dec.

20.

RasIns: Genetically Encoded Intrabodies of Activated Ras Proteins.

Cetin M, Evenson WE, Gross GG, Jalali-Yazdi F, Krieger D, Arnold D, Takahashi TT, Roberts RW.

J Mol Biol. 2017 Feb 17;429(4):562-573. doi: 10.1016/j.jmb.2016.11.008. Epub 2016 Nov 16.

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