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Tannic acid inhibits EGFR/STAT1/3 and enhances p38/STAT1 signalling axis in breast cancer cells.

Darvin P, Joung YH, Kang DY, Sp N, Byun HJ, Hwang TS, Sasidharakurup H, Lee CH, Cho KH, Park KD, Lee HK, Yang YM.

J Cell Mol Med. 2017 Apr;21(4):720-734. doi: 10.1111/jcmm.13015. Epub 2016 Nov 15.


Elevated STAT3 expression in ovarian cancer ascites promotes invasion and metastasis: a potential therapeutic target.

Saini U, Naidu S, ElNaggar AC, Bid HK, Wallbillich JJ, Bixel K, Bolyard C, Suarez AA, Kaur B, Kuppusamy P, Hays J, Goodfellow PJ, Cohn DE, Selvendiran K.

Oncogene. 2017 Jan 12;36(2):168-181. doi: 10.1038/onc.2016.197. Epub 2016 Jun 13.


STATs: An Old Story, Yet Mesmerizing.

Abroun S, Saki N, Ahmadvand M, Asghari F, Salari F, Rahim F.

Cell J. 2015 Fall;17(3):395-411. Epub 2015 Oct 7. Review.


Protein tyrosine kinase 6 promotes ERBB2-induced mammary gland tumorigenesis in the mouse.

Peng M, Ball-Kell SM, Tyner AL.

Cell Death Dis. 2015 Aug 6;6:e1848. doi: 10.1038/cddis.2015.210.


Upregulation of TPX2 by STAT3: identification of a novel STAT3 binding site.

Cocchiola R, Grillo C, Altieri F, Chichiarelli S, Turano C, Eufemi M.

PLoS One. 2014 Nov 17;9(11):e113096. doi: 10.1371/journal.pone.0113096. eCollection 2014.


STAT3 Target Genes Relevant to Human Cancers.

Carpenter RL, Lo HW.

Cancers (Basel). 2014 Apr 16;6(2):897-925. doi: 10.3390/cancers6020897.


Monoallelic loss of tumor suppressor GRIM-19 promotes tumorigenesis in mice.

Kalakonda S, Nallar SC, Jaber S, Keay SK, Rorke E, Munivenkatappa R, Lindner DJ, Fiskum GM, Kalvakolanu DV.

Proc Natl Acad Sci U S A. 2013 Nov 5;110(45):E4213-22. doi: 10.1073/pnas.1303760110. Epub 2013 Oct 21.


Critical analysis of the potential for targeting STAT3 in human malignancy.

Peyser ND, Grandis JR.

Onco Targets Ther. 2013 Jul 30;6:999-1010. doi: 10.2147/OTT.S47903. Print 2013.


STAT3 negatively regulates thyroid tumorigenesis.

Couto JP, Daly L, Almeida A, Knauf JA, Fagin JA, Sobrinho-Simões M, Lima J, Máximo V, Soares P, Lyden D, Bromberg JF.

Proc Natl Acad Sci U S A. 2012 Aug 28;109(35):E2361-70. doi: 10.1073/pnas.1201232109. Epub 2012 Aug 13.


Targeting Stat3 abrogates EGFR inhibitor resistance in cancer.

Sen M, Joyce S, Panahandeh M, Li C, Thomas SM, Maxwell J, Wang L, Gooding WE, Johnson DE, Grandis JR.

Clin Cancer Res. 2012 Sep 15;18(18):4986-96. doi: 10.1158/1078-0432.CCR-12-0792. Epub 2012 Jul 23.


STAT1 gene expression is enhanced by nuclear EGFR and HER2 via cooperation with STAT3.

Han W, Carpenter RL, Cao X, Lo HW.

Mol Carcinog. 2013 Dec;52(12):959-69. doi: 10.1002/mc.21936. Epub 2012 Jun 12.


Effects of magnolol on UVB-induced skin cancer development in mice and its possible mechanism of action.

Chilampalli C, Guillermo R, Zhang X, Kaushik RS, Young A, Zeman D, Hildreth MB, Fahmy H, Dwivedi C.

BMC Cancer. 2011 Oct 20;11:456. doi: 10.1186/1471-2407-11-456.


Investigation into the biological properties of the olive polyphenol, hydroxytyrosol: mechanistic insights by genome-wide mRNA-Seq analysis.

Rafehi H, Smith AJ, Balcerczyk A, Ziemann M, Ooi J, Loveridge SJ, Baker EK, El-Osta A, Karagiannis TC.

Genes Nutr. 2012 Apr;7(2):343-55. doi: 10.1007/s12263-011-0249-3. Epub 2011 Sep 28.


STAT6 expression in glioblastoma promotes invasive growth.

Merk BC, Owens JL, Lopes MB, Silva CM, Hussaini IM.

BMC Cancer. 2011 May 20;11:184. doi: 10.1186/1471-2407-11-184.


HGF/c-met/Stat3 signaling during skin tumor cell invasion: indications for a positive feedback loop.

Syed ZA, Yin W, Hughes K, Gill JN, Shi R, Clifford JL.

BMC Cancer. 2011 May 19;11:180. doi: 10.1186/1471-2407-11-180.


Gambogic acid inhibits STAT3 phosphorylation through activation of protein tyrosine phosphatase SHP-1: potential role in proliferation and apoptosis.

Prasad S, Pandey MK, Yadav VR, Aggarwal BB.

Cancer Prev Res (Phila). 2011 Jul;4(7):1084-94. doi: 10.1158/1940-6207.CAPR-10-0340. Epub 2011 Apr 13.


LYR71, a derivative of trimeric resveratrol, inhibits tumorigenesis by blocking STAT3-mediated matrix metalloproteinase 9 expression.

Kim JE, Kim HS, Shin YJ, Lee CS, Won C, Lee SA, Lee JW, Kim Y, Kang JS, Ye SK, Chung MH.

Exp Mol Med. 2008 Oct 31;40(5):514-22.


IFNalpha and IFNlambda differ in their antiproliferative effects and duration of JAK/STAT signaling activity.

Maher SG, Sheikh F, Scarzello AJ, Romero-Weaver AL, Baker DP, Donnelly RP, Gamero AM.

Cancer Biol Ther. 2008 Jul;7(7):1109-15. Epub 2008 Apr 24.


Loss of protein inhibitors of activated STAT-3 expression in glioblastoma multiforme tumors: implications for STAT-3 activation and gene expression.

Brantley EC, Nabors LB, Gillespie GY, Choi YH, Palmer CA, Harrison K, Roarty K, Benveniste EN.

Clin Cancer Res. 2008 Aug 1;14(15):4694-704. doi: 10.1158/1078-0432.CCR-08-0618.

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