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Histologically defined intratumoral sequencing uncovers evolutionary cues into conserved molecular events driving gliomagenesis.

Prabhu A, Kesarwani P, Kant S, Graham SF, Chinnaiyan P.

Neuro Oncol. 2017 Nov 29;19(12):1599-1606. doi: 10.1093/neuonc/nox100.


The retinoblastoma protein regulates hypoxia-inducible genetic programs, tumor cell invasiveness and neuroendocrine differentiation in prostate cancer cells.

Labrecque MP, Takhar MK, Nason R, Santacruz S, Tam KJ, Massah S, Haegert A, Bell RH, Altamirano-Dimas M, Collins CC, Lee FJ, Prefontaine GG, Cox ME, Beischlag TV.

Oncotarget. 2016 Apr 26;7(17):24284-302. doi: 10.18632/oncotarget.8301.


NDRG1 promotes growth of hepatocellular carcinoma cells by directly interacting with GSK-3β and Nur77 to prevent β-catenin degradation.

Lu WJ, Chua MS, Wei W, So SK.

Oncotarget. 2015 Oct 6;6(30):29847-59. doi: 10.18632/oncotarget.4913.


Role of GLI1 and NDRG1 in Increased Resistance to Apoptosis Induction.

Wu F, Rom WN, Koshiji M, Mo Y, Hosomi Y, Tchou-Wong KM.

J Environ Pathol Toxicol Oncol. 2015;34(3):213-25.


MicroRNA-769-3p down-regulates NDRG1 and enhances apoptosis in MCF-7 cells during reoxygenation.

Luo EC, Chang YC, Sher YP, Huang WY, Chuang LL, Chiu YC, Tsai MH, Chuang EY, Lai LC.

Sci Rep. 2014 Aug 1;4:5908. doi: 10.1038/srep05908.


The metastasis suppressor, N-myc downstream-regulated gene 1 (NDRG1), inhibits stress-induced autophagy in cancer cells.

Sahni S, Bae DH, Lane DJ, Kovacevic Z, Kalinowski DS, Jansson PJ, Richardson DR.

J Biol Chem. 2014 Apr 4;289(14):9692-709. doi: 10.1074/jbc.M113.529511. Epub 2014 Feb 15.


Global gene expression analysis reveals a link between NDRG1 and vesicle transport.

Askautrud HA, Gjernes E, Gunnes G, Sletten M, Ross DT, Børresen-Dale AL, Iversen N, Tranulis MA, Frengen E.

PLoS One. 2014 Jan 31;9(1):e87268. doi: 10.1371/journal.pone.0087268. eCollection 2014.


FOXD3 is a novel tumor suppressor that affects growth, invasion, metastasis and angiogenesis of neuroblastoma.

Li D, Mei H, Qi M, Yang D, Zhao X, Xiang X, Pu J, Huang K, Zheng L, Tong Q.

Oncotarget. 2013 Nov;4(11):2021-44.


Association of Differentiation-Related Gene-1 (DRG1) with Breast Cancer Survival and in Vitro Impact of DRG1 Suppression.

Baig RM, Sanders AJ, Kayani MA, Jiang WG.

Cancers (Basel). 2012 Jul 10;4(3):658-72. doi: 10.3390/cancers4030658.


Quantitative molecular phenotyping of gill remodeling in a cichlid fish responding to salinity stress.

Kültz D, Li J, Gardell A, Sacchi R.

Mol Cell Proteomics. 2013 Dec;12(12):3962-75. doi: 10.1074/mcp.M113.029827. Epub 2013 Sep 24.


Variable metastatic potentials correlate with differential plectin and vimentin expression in syngeneic androgen independent prostate cancer cells.

Burch TC, Watson MT, Nyalwidhe JO.

PLoS One. 2013 May 22;8(5):e65005. doi: 10.1371/journal.pone.0065005. Print 2013.


Proteolytic cleavage and truncation of NDRG1 in human prostate cancer cells, but not normal prostate epithelial cells.

Ghalayini MK, Dong Q, Richardson DR, Assinder SJ.

Biosci Rep. 2013 Jun 11;33(3). pii: e00042. doi: 10.1042/BSR20130042.


AKT inhibitor suppresses hyperthermia-induced Ndrg2 phosphorylation in gastric cancer cells.

Tao Y, Guo Y, Liu W, Zhang J, Li X, Shen L, Ru Y, Xue Y, Zheng J, Liu X, Zhang J, Yao L.

Braz J Med Biol Res. 2013 Apr;46(4):394-404. Epub 2013 Apr 5.


N-myc downstream regulated 1 (NDRG1) is regulated by eukaryotic initiation factor 3a (eIF3a) during cellular stress caused by iron depletion.

Lane DJ, Saletta F, Suryo Rahmanto Y, Kovacevic Z, Richardson DR.

PLoS One. 2013;8(2):e57273. doi: 10.1371/journal.pone.0057273. Epub 2013 Feb 21. Erratum in: PLoS One. 2016;11(2):e0149922.


Molecular profiles of pre- and postoperative breast cancer tumours reveal differentially expressed genes.

Riis ML, Lüders T, Markert EK, Haakensen VD, Nesbakken AJ, Kristensen VN, Bukholm IR.

ISRN Oncol. 2012;2012:450267. doi: 10.5402/2012/450267. Epub 2012 Nov 26.


Oncogenic but non-essential role of N-myc downstream regulated gene 1 in the progression of esophageal squamous cell carcinoma.

Wei W, Bracher-Manecke JC, Zhao X, Davies NH, Zhou L, Ai R, Oliver L, Vallette F, Hendricks DT.

Cancer Biol Ther. 2013 Feb;14(2):164-74. doi: 10.4161/cbt.22956. Epub 2012 Nov 28.


TMEM45A is essential for hypoxia-induced chemoresistance in breast and liver cancer cells.

Flamant L, Roegiers E, Pierre M, Hayez A, Sterpin C, De Backer O, Arnould T, Poumay Y, Michiels C.

BMC Cancer. 2012 Sep 6;12:391. doi: 10.1186/1471-2407-12-391.


Inhibition of N-Myc down regulated gene 1 in in vitro cultured human glioblastoma cells.

Said HM, Polat B, Stein S, Guckenberger M, Hagemann C, Staab A, Katzer A, Anacker J, Flentje M, Vordermark D.

World J Clin Oncol. 2012 Jul 10;3(7):104-10. doi: 10.5306/wjco.v3.i7.104.


The iron chelators Dp44mT and DFO inhibit TGF-β-induced epithelial-mesenchymal transition via up-regulation of N-Myc downstream-regulated gene 1 (NDRG1).

Chen Z, Zhang D, Yue F, Zheng M, Kovacevic Z, Richardson DR.

J Biol Chem. 2012 May 18;287(21):17016-28. doi: 10.1074/jbc.M112.350470. Epub 2012 Mar 27.


The indolic diet-derivative, 3,3'-diindolylmethane, induced apoptosis in human colon cancer cells through upregulation of NDRG1.

Lerner A, Grafi-Cohen M, Napso T, Azzam N, Fares F.

J Biomed Biotechnol. 2012;2012:256178. doi: 10.1155/2012/256178. Epub 2011 Nov 13.

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