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Expression and Processing of Amyloid Precursor Protein in Vascular Endothelium.

d'Uscio LV, He T, Katusic ZS.

Physiology (Bethesda). 2017 Jan;32(1):20-32. Review.


β-Amyloid in CSF: Biomarker for preclinical cerebral amyloid angiopathy.

van Etten ES, Verbeek MM, van der Grond J, Zielman R, van Rooden S, van Zwet EW, van Opstal AM, Haan J, Greenberg SM, van Buchem MA, Wermer MJ, Terwindt GM.

Neurology. 2017 Jan 10;88(2):169-176. doi: 10.1212/WNL.0000000000003486. Epub 2016 Nov 30.


Lysosomal dysfunction in the brain of a mouse model with intraneuronal accumulation of carboxyl terminal fragments of the amyloid precursor protein.

Kaur G, Pawlik M, Gandy SE, Ehrlich ME, Smiley JF, Levy E.

Mol Psychiatry. 2016 Oct 25. doi: 10.1038/mp.2016.189. [Epub ahead of print]


The impact of cerebrovascular aging on vascular cognitive impairment and dementia.

Yang T, Sun Y, Lu Z, Leak RK, Zhang F.

Ageing Res Rev. 2017 Mar;34:15-29. doi: 10.1016/j.arr.2016.09.007. Epub 2016 Sep 28. Review.


Development of Cerebral Microbleeds in the APP23-Transgenic Mouse Model of Cerebral Amyloid Angiopathy-A 9.4 Tesla MRI Study.

Reuter B, Venus A, Heiler P, Schad L, Ebert A, Hennerici MG, Grudzenski S, Fatar M.

Front Aging Neurosci. 2016 Jul 8;8:170. doi: 10.3389/fnagi.2016.00170. eCollection 2016.


Intracerebral haemorrhage in Down syndrome: protected or predisposed?

Buss L, Fisher E, Hardy J, Nizetic D, Groet J, Pulford L, Strydom A.

F1000Res. 2016 May 12;5. pii: F1000 Faculty Rev-876. doi: 10.12688/f1000research.7819.1. eCollection 2016. Review.


Vascular basement membranes as pathways for the passage of fluid into and out of the brain.

Morris AW, Sharp MM, Albargothy NJ, Fernandes R, Hawkes CA, Verma A, Weller RO, Carare RO.

Acta Neuropathol. 2016 May;131(5):725-36. doi: 10.1007/s00401-016-1555-z. Epub 2016 Mar 14.


Interictal spikes during sleep are an early defect in the Tg2576 mouse model of β-amyloid neuropathology.

Kam K, Duffy ÁM, Moretto J, LaFrancois JJ, Scharfman HE.

Sci Rep. 2016 Jan 28;6:20119. doi: 10.1038/srep20119.


Vascular cognitive impairment: Modeling a critical neurologic disease in vitro and in vivo.

Helman AM, Murphy MP.

Biochim Biophys Acta. 2016 May;1862(5):975-82. doi: 10.1016/j.bbadis.2015.12.009. Epub 2015 Dec 17. Review.


Murine versus human apolipoprotein E4: differential facilitation of and co-localization in cerebral amyloid angiopathy and amyloid plaques in APP transgenic mouse models.

Liao F, Zhang TJ, Jiang H, Lefton KB, Robinson GO, Vassar R, Sullivan PM, Holtzman DM.

Acta Neuropathol Commun. 2015 Nov 10;3:70. doi: 10.1186/s40478-015-0250-y.


Tissue Transglutaminase and Its Product Isopeptide Are Increased in Alzheimer's Disease and APPswe/PS1dE9 Double Transgenic Mice Brains.

Zhang J, Wang S, Huang W, Bennett DA, Dickson DW, Wang D, Wang R.

Mol Neurobiol. 2016 Oct;53(8):5066-78. doi: 10.1007/s12035-015-9413-x. Epub 2015 Sep 19.


APOE and cerebral amyloid angiopathy in community-dwelling older persons.

Yu L, Boyle PA, Nag S, Leurgans S, Buchman AS, Wilson RS, Arvanitakis Z, Farfel JM, De Jager PL, Bennett DA, Schneider JA.

Neurobiol Aging. 2015 Nov;36(11):2946-53. doi: 10.1016/j.neurobiolaging.2015.08.008. Epub 2015 Aug 15.


A novel BACE inhibitor NB-360 shows a superior pharmacological profile and robust reduction of amyloid-β and neuroinflammation in APP transgenic mice.

Neumann U, Rueeger H, Machauer R, Veenstra SJ, Lueoend RM, Tintelnot-Blomley M, Laue G, Beltz K, Vogg B, Schmid P, Frieauff W, Shimshek DR, Staufenbiel M, Jacobson LH.

Mol Neurodegener. 2015 Sep 3;10:44. doi: 10.1186/s13024-015-0033-8.


Ischemic brain injury in cerebral amyloid angiopathy.

Reijmer YD, van Veluw SJ, Greenberg SM.

J Cereb Blood Flow Metab. 2016 Jan;36(1):40-54. Review.


Minocycline reduces spontaneous hemorrhage in mouse models of cerebral amyloid angiopathy.

Yan P, Zhu A, Liao F, Xiao Q, Kraft AW, Gonzales E, Perez R, Greenberg SM, Holtzman DM, Lee JM.

Stroke. 2015 Jun;46(6):1633-40. doi: 10.1161/STROKEAHA.115.008582. Epub 2015 May 5.


Vascular contributions to cognitive impairment and dementia including Alzheimer's disease.

Snyder HM, Corriveau RA, Craft S, Faber JE, Greenberg SM, Knopman D, Lamb BT, Montine TJ, Nedergaard M, Schaffer CB, Schneider JA, Wellington C, Wilcock DM, Zipfel GJ, Zlokovic B, Bain LJ, Bosetti F, Galis ZS, Koroshetz W, Carrillo MC.

Alzheimers Dement. 2015 Jun;11(6):710-7. doi: 10.1016/j.jalz.2014.10.008. Epub 2014 Dec 12. Review.


Octodon degus: a strong attractor for Alzheimer research.

Castro-Fuentes R, Socas-Pérez R.

Basic Clin Neurosci. 2013 Winter;4(1):91-6.


Altered synaptic structure in the hippocampus in a mouse model of Alzheimer's disease with soluble amyloid-β oligomers and no plaque pathology.

Price KA, Varghese M, Sowa A, Yuk F, Brautigam H, Ehrlich ME, Dickstein DL.

Mol Neurodegener. 2014 Oct 13;9:41. doi: 10.1186/1750-1326-9-41.


The Cerebrovascular Basement Membrane: Role in the Clearance of β-amyloid and Cerebral Amyloid Angiopathy.

Morris AW, Carare RO, Schreiber S, Hawkes CA.

Front Aging Neurosci. 2014 Sep 19;6:251. doi: 10.3389/fnagi.2014.00251. eCollection 2014. Review.

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