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Items: 1 to 20 of 31

1.

Engineered heparins as new anticoagulant drugs.

Vaidyanathan D, Williams A, Dordick JS, Koffas MAG, Linhardt RJ.

Bioeng Transl Med. 2017 Mar;2(1):17-30. doi: 10.1002/btm2.10042. Epub 2016 Nov 21. Review.

2.

Synthesis of 3-O-Sulfated Oligosaccharides to Understand the Relationship between Structures and Functions of Heparan Sulfate.

Wang Z, Hsieh PH, Xu Y, Thieker D, Chai EJ, Xie S, Cooley B, Woods RJ, Chi L, Liu J.

J Am Chem Soc. 2017 Apr 3. doi: 10.1021/jacs.7b01923. [Epub ahead of print]

PMID:
28340300
3.

Structure Based Substrate Specificity Analysis of Heparan Sulfate 6-O-Sulfotransferases.

Xu Y, Moon AF, Xu S, Krahn JM, Liu J, Pedersen LC.

ACS Chem Biol. 2017 Jan 20;12(1):73-82. doi: 10.1021/acschembio.6b00841. Epub 2016 Nov 22.

4.

Structural Analysis of Heparin-Derived 3-O-Sulfated Tetrasaccharides: Antithrombin Binding Site Variants.

Chen Y, Lin L, Agyekum I, Zhang X, St Ange K, Yu Y, Zhang F, Liu J, Amster IJ, Linhardt RJ.

J Pharm Sci. 2017 Apr;106(4):973-981. doi: 10.1016/j.xphs.2016.11.023. Epub 2016 Dec 20.

5.

Bioengineered heparins and heparan sulfates.

Fu L, Suflita M, Linhardt RJ.

Adv Drug Deliv Rev. 2016 Feb 1;97:237-49. doi: 10.1016/j.addr.2015.11.002. Epub 2015 Nov 10. Review.

6.
7.

Heparin and related polysaccharides: synthesis using recombinant enzymes and metabolic engineering.

Suflita M, Fu L, He W, Koffas M, Linhardt RJ.

Appl Microbiol Biotechnol. 2015 Sep;99(18):7465-79. doi: 10.1007/s00253-015-6821-9. Epub 2015 Jul 29. Review.

8.

Comprehensive analysis of herpes simplex virus 1 (HSV-1) entry mediated by zebrafish 3-O-Sulfotransferase isoforms: implications for the development of a zebrafish model of HSV-1 infection.

Yakoub AM, Rawal N, Maus E, Baldwin J, Shukla D, Tiwari V.

J Virol. 2014 Nov;88(21):12915-22. doi: 10.1128/JVI.02071-14. Epub 2014 Aug 20.

9.

Docking server for the identification of heparin binding sites on proteins.

Mottarella SE, Beglov D, Beglova N, Nugent MA, Kozakov D, Vajda S.

J Chem Inf Model. 2014 Jul 28;54(7):2068-78. doi: 10.1021/ci500115j. Epub 2014 Jul 10.

10.

Molecular mechanism of substrate specificity for heparan sulfate 2-O-sulfotransferase.

Liu C, Sheng J, Krahn JM, Perera L, Xu Y, Hsieh PH, Dou W, Liu J, Pedersen LC.

J Biol Chem. 2014 May 9;289(19):13407-18. doi: 10.1074/jbc.M113.530535. Epub 2014 Mar 20.

11.

Heparan sulfate 3-O-sulfation: a rare modification in search of a function.

Thacker BE, Xu D, Lawrence R, Esko JD.

Matrix Biol. 2014 Apr;35:60-72. doi: 10.1016/j.matbio.2013.12.001. Epub 2013 Dec 19. Review.

12.

Crystal structure of human tyrosylprotein sulfotransferase-2 reveals the mechanism of protein tyrosine sulfation reaction.

Teramoto T, Fujikawa Y, Kawaguchi Y, Kurogi K, Soejima M, Adachi R, Nakanishi Y, Mishiro-Sato E, Liu MC, Sakakibara Y, Suiko M, Kimura M, Kakuta Y.

Nat Commun. 2013;4:1572. doi: 10.1038/ncomms2593.

13.

Structural basis of functional group activation by sulfotransferases in complex metabolic pathways.

McCarthy JG, Eisman EB, Kulkarni S, Gerwick L, Gerwick WH, Wipf P, Sherman DH, Smith JL.

ACS Chem Biol. 2012 Dec 21;7(12):1994-2003. doi: 10.1021/cb300385m. Epub 2012 Sep 26.

14.

Understanding the substrate specificity of the heparan sulfate sulfotransferases by an integrated biosynthetic and crystallographic approach.

Liu J, Moon AF, Sheng J, Pedersen LC.

Curr Opin Struct Biol. 2012 Oct;22(5):550-7. doi: 10.1016/j.sbi.2012.07.004. Epub 2012 Jul 26. Review.

15.
16.

Dissecting the substrate recognition of 3-O-sulfotransferase for the biosynthesis of anticoagulant heparin.

Moon AF, Xu Y, Woody SM, Krahn JM, Linhardt RJ, Liu J, Pedersen LC.

Proc Natl Acad Sci U S A. 2012 Apr 3;109(14):5265-70. doi: 10.1073/pnas.1117923109. Epub 2012 Mar 19.

17.

A synthetic heparan sulfate oligosaccharide library reveals the novel enzymatic action of D-glucosaminyl 3-O-sulfotransferase-3a.

Nguyen TK, Arungundram S, Tran VM, Raman K, Al-Mafraji K, Venot A, Boons GJ, Kuberan B.

Mol Biosyst. 2012 Feb;8(2):609-14. doi: 10.1039/c1mb05221g. Epub 2011 Nov 24.

18.

Catalytic mechanism of Golgi-resident human tyrosylprotein sulfotransferase-2: a mass spectrometry approach.

Danan LM, Yu Z, Ludden PJ, Jia W, Moore KL, Leary JA.

J Am Soc Mass Spectrom. 2010 Sep;21(9):1633-42. doi: 10.1016/j.jasms.2010.03.037. Epub 2010 Apr 2.

19.

Using engineered 2-O-sulfotransferase to determine the activity of heparan sulfate C5-epimerase and its mutants.

Li K, Bethea HN, Liu J.

J Biol Chem. 2010 Apr 9;285(15):11106-13. doi: 10.1074/jbc.M109.081059. Epub 2010 Jan 29.

20.

A turn-like structure "KKPE" segment mediates the specific binding of viral protein A27 to heparin and heparan sulfate on cell surfaces.

Shih PC, Yang MS, Lin SC, Ho Y, Hsiao JC, Wang DR, Yu SS, Chang W, Tzou DL.

J Biol Chem. 2009 Dec 25;284(52):36535-46. doi: 10.1074/jbc.M109.037267. Epub 2009 Oct 26.

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