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Items: 19


Knowledge-driven binning approach for rare variant association analysis: application to neuroimaging biomarkers in Alzheimer's disease.

Kim D, Basile AO, Bang L, Horgusluoglu E, Lee S, Ritchie MD, Saykin AJ, Nho K.

BMC Med Inform Decis Mak. 2017 May 18;17(Suppl 1):61. doi: 10.1186/s12911-017-0454-0.


Fancb deficiency impairs hematopoietic stem cell function.

Du W, Amarachintha S, Erden O, Wilson A, Meetei AR, Andreassen PR, Namekawa SH, Pang Q.

Sci Rep. 2015 Dec 11;5:18127. doi: 10.1038/srep18127.


Oxidative stress-associated protein tyrosine kinases and phosphatases in Fanconi anemia.

Li J, Pang Q.

Antioxid Redox Signal. 2014 May 10;20(14):2290-301. doi: 10.1089/ars.2013.5715. Epub 2014 Mar 11. Review.


FANCL ubiquitinates β-catenin and enhances its nuclear function.

Dao KH, Rotelli MD, Petersen CL, Kaech S, Nelson WD, Yates JE, Hanlon Newell AE, Olson SB, Druker BJ, Bagby GC.

Blood. 2012 Jul 12;120(2):323-34. doi: 10.1182/blood-2011-11-388355. Epub 2012 May 31.


Fanconi anemia links reactive oxygen species to insulin resistance and obesity.

Li J, Sipple J, Maynard S, Mehta PA, Rose SR, Davies SM, Pang Q.

Antioxid Redox Signal. 2012 Oct 15;17(8):1083-98. doi: 10.1089/ars.2011.4417. Epub 2012 Jun 25.


p38 MAPK inhibition suppresses the TLR-hypersensitive phenotype in FANCC- and FANCA-deficient mononuclear phagocytes.

Anur P, Yates J, Garbati MR, Vanderwerf S, Keeble W, Rathbun K, Hays LE, Tyner JW, Svahn J, Cappelli E, Dufour C, Bagby GC.

Blood. 2012 Mar 1;119(9):1992-2002. doi: 10.1182/blood-2011-06-354647. Epub 2012 Jan 10.


Fanconi anemia complementation group A (FANCA) protein has intrinsic affinity for nucleic acids with preference for single-stranded forms.

Yuan F, Qian L, Zhao X, Liu JY, Song L, D'Urso G, Jain C, Zhang Y.

J Biol Chem. 2012 Feb 10;287(7):4800-7. doi: 10.1074/jbc.M111.315366. Epub 2011 Dec 21.


The role of stat1b in zebrafish hematopoiesis.

Song H, Yan YL, Titus T, He X, Postlethwait JH.

Mech Dev. 2011 Sep-Dec;128(7-10):442-56. doi: 10.1016/j.mod.2011.08.004. Epub 2011 Sep 3.


Direct inhibition of TNF-α promoter activity by Fanconi anemia protein FANCD2.

Matsushita N, Endo Y, Sato K, Kurumizaka H, Yamashita T, Takata M, Yanagi S.

PLoS One. 2011;6(8):e23324. doi: 10.1371/journal.pone.0023324. Epub 2011 Aug 31.


Sex reversal in zebrafish fancl mutants is caused by Tp53-mediated germ cell apoptosis.

Rodríguez-Marí A, Cañestro C, Bremiller RA, Nguyen-Johnson A, Asakawa K, Kawakami K, Postlethwait JH.

PLoS Genet. 2010 Jul 22;6(7):e1001034. doi: 10.1371/journal.pgen.1001034.


Genetic disruption of both Fancc and Fancg in mice recapitulates the hematopoietic manifestations of Fanconi anemia.

Pulliam-Leath AC, Ciccone SL, Nalepa G, Li X, Si Y, Miravalle L, Smith D, Yuan J, Li J, Anur P, Orazi A, Vance GH, Yang FC, Hanenberg H, Bagby GC, Clapp DW.

Blood. 2010 Oct 21;116(16):2915-20. doi: 10.1182/blood-2009-08-240747. Epub 2010 Jul 6.


Several tetratricopeptide repeat (TPR) motifs of FANCG are required for assembly of the BRCA2/D1-D2-G-X3 complex, FANCD2 monoubiquitylation and phleomycin resistance.

Wilson JB, Blom E, Cunningham R, Xiao Y, Kupfer GM, Jones NJ.

Mutat Res. 2010 Jul 7;689(1-2):12-20. doi: 10.1016/j.mrfmmm.2010.04.003. Epub 2010 May 5.


TLR8-dependent TNF-(alpha) overexpression in Fanconi anemia group C cells.

Vanderwerf SM, Svahn J, Olson S, Rathbun RK, Harrington C, Yates J, Keeble W, Anderson DC, Anur P, Pereira NF, Pilonetto DV, Pasquini R, Bagby GC.

Blood. 2009 Dec 17;114(26):5290-8. doi: 10.1182/blood-2009-05-222414. Epub 2009 Oct 22.


Mouse models of Fanconi anemia.

Parmar K, D'Andrea A, Niedernhofer LJ.

Mutat Res. 2009 Jul 31;668(1-2):133-40. doi: 10.1016/j.mrfmmm.2009.03.015. Epub 2009 Apr 10. Review.


Myelodysplasia and acute leukemia as late complications of marrow failure: future prospects for leukemia prevention.

Bagby GC, Meyers G.

Hematol Oncol Clin North Am. 2009 Apr;23(2):361-76. doi: 10.1016/j.hoc.2009.01.006. Review.


The Fanconi anemia pathway and ubiquitin.

Jacquemont C, Taniguchi T.

BMC Biochem. 2007 Nov 22;8 Suppl 1:S10. Review.


Continuous in vivo infusion of interferon-gamma (IFN-gamma) enhances engraftment of syngeneic wild-type cells in Fanca-/- and Fancg-/- mice.

Si Y, Ciccone S, Yang FC, Yuan J, Zeng D, Chen S, van de Vrugt HJ, Critser J, Arwert F, Haneline LS, Clapp DW.

Blood. 2006 Dec 15;108(13):4283-7. Epub 2006 Aug 31.


RAX, the PKR activator, sensitizes cells to inflammatory cytokines, serum withdrawal, chemotherapy, and viral infection.

Bennett RL, Blalock WL, Abtahi DM, Pan Y, Moyer SA, May WS.

Blood. 2006 Aug 1;108(3):821-9.


Enhanced TNF-alpha-induced apoptosis in Fanconi anemia type C-deficient cells is dependent on apoptosis signal-regulating kinase 1.

Bijangi-Vishehsaraei K, Saadatzadeh MR, Werne A, McKenzie KA, Kapur R, Ichijo H, Haneline LS.

Blood. 2005 Dec 15;106(13):4124-30. Epub 2005 Aug 18.

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