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Systematic analysis of human telomeric dysfunction using inducible telosome/shelterin CRISPR/Cas9 knockout cells.

Kim H, Li F, He Q, Deng T, Xu J, Jin F, Coarfa C, Putluri N, Liu D, Songyang Z.

Cell Discov. 2017 Sep 26;3:17034. doi: 10.1038/celldisc.2017.34. eCollection 2017.


Telomeres and telomerase in prostate cancer development and therapy.

Graham MK, Meeker A.

Nat Rev Urol. 2017 Oct;14(10):607-619. doi: 10.1038/nrurol.2017.104. Epub 2017 Jul 4. Review.


Abnormal mRNA Expression Levels of Telomere-Binding Proteins Represent Biomarkers in Myelodysplastic Syndromes: A Case-Control Study.

Liu B, Yan R, Zhang J, Wang B, Sun H, Cui X.

Turk J Haematol. 2017 Aug 2;34(3):200-206. doi: 10.4274/tjh.2016.0364. Epub 2017 Apr 13.


Structural insights into POT1-TPP1 interaction and POT1 C-terminal mutations in human cancer.

Chen C, Gu P, Wu J, Chen X, Niu S, Sun H, Wu L, Li N, Peng J, Shi S, Fan C, Huang M, Wong CC, Gong Q, Kumar-Sinha C, Zhang R, Pusztai L, Rai R, Chang S, Lei M.

Nat Commun. 2017 Apr 10;8:14929. doi: 10.1038/ncomms14929.


Structural and functional analysis of the human POT1-TPP1 telomeric complex.

Rice C, Shastrula PK, Kossenkov AV, Hills R, Baird DM, Showe LC, Doukov T, Janicki S, Skordalakes E.

Nat Commun. 2017 Apr 10;8:14928. doi: 10.1038/ncomms14928.


Fundamental mechanisms of telomerase action in yeasts and mammals: understanding telomeres and telomerase in cancer cells.

Armstrong CA, Tomita K.

Open Biol. 2017 Mar;7(3). pii: 160338. doi: 10.1098/rsob.160338. Review.


Progress in Human and Tetrahymena Telomerase Structure Determination.

Chan H, Wang Y, Feigon J.

Annu Rev Biophys. 2017 May 22;46:199-225. doi: 10.1146/annurev-biophys-062215-011140. Epub 2017 Mar 15. Review.


Control of Cellular Aging, Tissue Function, and Cancer by p53 Downstream of Telomeres.

Roake CM, Artandi SE.

Cold Spring Harb Perspect Med. 2017 May 1;7(5). pii: a026088. doi: 10.1101/cshperspect.a026088. Review.


Telomere Recognition and Assembly Mechanism of Mammalian Shelterin.

Erdel F, Kratz K, Willcox S, Griffith JD, Greene EC, de Lange T.

Cell Rep. 2017 Jan 3;18(1):41-53. doi: 10.1016/j.celrep.2016.12.005.


Endogenous Telomerase Reverse Transcriptase N-Terminal Tagging Affects Human Telomerase Function at Telomeres In Vivo.

Chiba K, Vogan JM, Wu RA, Gill MS, Zhang X, Collins K, Hockemeyer D.

Mol Cell Biol. 2017 Jan 19;37(3). pii: e00541-16. doi: 10.1128/MCB.00541-16. Print 2017 Feb 1.


Pot1 OB-fold mutations unleash telomere instability to initiate tumorigenesis.

Gu P, Wang Y, Bisht KK, Wu L, Kukova L, Smith EM, Xiao Y, Bailey SM, Lei M, Nandakumar J, Chang S.

Oncogene. 2017 Apr 6;36(14):1939-1951. doi: 10.1038/onc.2016.405. Epub 2016 Nov 21.


Low p16INK4a Expression in Early Passage Human Prostate Basal Epithelial Cells Enables Immortalization by Telomerase Expression Alone.

Graham MK, Principessa L, Antony L, Meeker AK, Isaacs JT.

Prostate. 2017 Mar;77(4):374-384. doi: 10.1002/pros.23276. Epub 2016 Nov 8.


Structural and functional consequences of a disease mutation in the telomere protein TPP1.

Bisht K, Smith EM, Tesmer VM, Nandakumar J.

Proc Natl Acad Sci U S A. 2016 Nov 15;113(46):13021-13026. Epub 2016 Nov 2.


Dynamic peptides of human TPP1 fulfill diverse functions in telomere maintenance.

Rajavel M, Orban T, Xu M, Hernandez-Sanchez W, de la Fuente M, Palczewski K, Taylor DJ.

Nucleic Acids Res. 2016 Dec 1;44(21):10467-10479. Epub 2016 Sep 20.


Germ line mutations in shelterin complex genes are associated with familial chronic lymphocytic leukemia.

Speedy HE, Kinnersley B, Chubb D, Broderick P, Law PJ, Litchfield K, Jayne S, Dyer MJS, Dearden C, Follows GA, Catovsky D, Houlston RS.

Blood. 2016 Nov 10;128(19):2319-2326. doi: 10.1182/blood-2016-01-695692. Epub 2016 Aug 15.


De novo assembly and characterization of the Chinese three-keeled pond turtle (Mauremys reevesii) transcriptome: presence of longevity-related genes.

Yin H, Nie L, Zhao F, Zhou H, Li H, Dong X, Zhang H, Wang Y, Shi Q, Li J.

PeerJ. 2016 May 24;4:e2062. doi: 10.7717/peerj.2062. eCollection 2016.


An H2A Histone Isotype, H2ac, Associates with Telomere and Maintains Telomere Integrity.

Su CH, Cheng C, Tzeng TY, Lin IH, Hsu MT.

PLoS One. 2016 May 26;11(5):e0156378. doi: 10.1371/journal.pone.0156378. eCollection 2016.


Preferential extension of short telomeres induced by low extracellular pH.

Ge Y, Wu S, Xue Y, Tao J, Li F, Chen Y, Liu H, Ma W, Huang J, Zhao Y.

Nucleic Acids Res. 2016 Sep 30;44(17):8086-96. doi: 10.1093/nar/gkw464. Epub 2016 May 24.


POT1-TPP1 Binding and Unfolding of Telomere DNA Discriminates against Structural Polymorphism.

Mullins MR, Rajavel M, Hernandez-Sanchez W, de la Fuente M, Biendarra SM, Harris ME, Taylor DJ.

J Mol Biol. 2016 Jul 3;428(13):2695-708. doi: 10.1016/j.jmb.2016.04.031. Epub 2016 May 10.


Stop pulling my strings - what telomeres taught us about the DNA damage response.

Lazzerini-Denchi E, Sfeir A.

Nat Rev Mol Cell Biol. 2016 Jun;17(6):364-78. doi: 10.1038/nrm.2016.43. Epub 2016 May 11. Review.

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