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Computer modeling of epilepsy: opportunities for drug discovery.

Lytton WW.

Drug Discov Today Dis Models. 2016 Spring;19:27-30. doi: 10.1016/j.ddmod.2017.02.007. Epub 2017 Jun 3.


Otoprotective effects of ethosuximide in NOD/LtJ mice with age-related hearing loss.

Sang L, Zheng T, Min L, Zhang X, Ma X, Entenman S, Su Y, Zheng Q.

Int J Mol Med. 2017 Jul;40(1):146-154. doi: 10.3892/ijmm.2017.3004. Epub 2017 May 26.


Advances in Autoimmune Epilepsy Associated with Antibodies, Their Potential Pathogenic Molecular Mechanisms, and Current Recommended Immunotherapies.

Fang Z, Yang Y, Chen X, Zhang W, Xie Y, Chen Y, Liu Z, Yuan W.

Front Immunol. 2017 Apr 25;8:395. doi: 10.3389/fimmu.2017.00395. eCollection 2017. Review.


Integrated network analysis reveals potentially novel molecular mechanisms and therapeutic targets of refractory epilepsies.

Chu H, Sun P, Yin J, Liu G, Wang Y, Zhao P, Zhu Y, Yang X, Zheng T, Zhou X, Jin W, Sun C.

PLoS One. 2017 Apr 7;12(4):e0174964. doi: 10.1371/journal.pone.0174964. eCollection 2017.


A Novel Strategy for Attenuating Opioid Withdrawal in Neonates.

Santoro GC, Shukla S, Patel K, Kaczmarzyk J, Agorastos S, Scherrer S, Choi YY, Veith C, Carrion J, Silverman R, Mullin D, Ahmed M, Schiffer WK, Brodie JD, Dewey SL.

J Addict Res Ther. 2016 Aug;7(4). pii: 291. doi: 10.4172/2155-6105.1000291. Epub 2016 Aug 11.


Review: Cav2.3 R-type Voltage-Gated Ca2+ Channels - Functional Implications in Convulsive and Non-convulsive Seizure Activity.

Wormuth C, Lundt A, Henseler C, Müller R, Broich K, Papazoglou A, Weiergräber M.

Open Neurol J. 2016 Sep 30;10:99-126. eCollection 2016.


Neurological teratogenic effects of antiepileptic drugs during pregnancy.

Nie Q, Su B, Wei J.

Exp Ther Med. 2016 Oct;12(4):2400-2404. Epub 2016 Aug 29.


Current Status of the New Antiepileptic Drugs in Chronic Pain.

Sidhu HS, Sadhotra A.

Front Pharmacol. 2016 Aug 25;7:276. doi: 10.3389/fphar.2016.00276. eCollection 2016. Review.


Comparative effects of α2δ-1 ligands in mouse models of colonic hypersensitivity.

Meleine M, Boudieu L, Gelot A, Muller E, Lashermes A, Matricon J, Silberberg C, Theodorou V, Eschalier A, Ardid D, Carvalho FA.

World J Gastroenterol. 2016 Aug 21;22(31):7111-23. doi: 10.3748/wjg.v22.i31.7111.


Antiepileptic drug use in a nursing home setting: a retrospective study in older adults.

Callegari C, Ielmini M, Bianchi L, Lucano M, Bertù L, Vender S.

Funct Neurol. 2016 Apr-Jun;31(2):87-93.


Antinociceptive Effects of the Serotonin and Noradrenaline Reuptake Inhibitors Milnacipran and Duloxetine on Vincristine-Induced Neuropathic Pain Model in Mice.

Katsuyama S, Aso H, Otowa A, Yagi T, Kishikawa Y, Komatsu T, Sakurada T, Nakamura H.

ISRN Pain. 2014 Feb 23;2014:915464. doi: 10.1155/2014/915464. eCollection 2014.


Resveratrol attenuates cortical neuron activity: roles of large conductance calcium-activated potassium channels and voltage-gated sodium channels.

Wang YJ, Chan MH, Chen L, Wu SN, Chen HH.

J Biomed Sci. 2016 May 21;23(1):47. doi: 10.1186/s12929-016-0259-y.


Novel antiepileptic drug lacosamide exerts neuroprotective effects by decreasing glial activation in the hippocampus of a gerbil model of ischemic stroke.

Ahn JY, Yan BC, Park JH, Ahn JH, Lee DH, Kim IH, Cho JH, Chen BH, Lee JC, Cho YS, Shin MC, Cho JH, Hong S, Won MH, Kim SK.

Exp Ther Med. 2015 Dec;10(6):2007-2014. Epub 2015 Oct 13.


Treatment of Generalized Convulsive Status Epilepticus in Pediatric Patients.

Alford EL, Wheless JW, Phelps SJ.

J Pediatr Pharmacol Ther. 2015 Jul-Aug;20(4):260-89. doi: 10.5863/1551-6776-20.4.260. Review.


Next steps for birth defects research and prevention: The birth defects study to evaluate pregnancy exposures (BD-STEPS).

Tinker SC, Carmichael SL, Anderka M, Browne ML, Caspers Conway KM, Meyer RE, Nembhard WN, Olney RS, Reefhuis J; Birth Defects Study To Evaluate Pregnancy exposureS.

Birth Defects Res A Clin Mol Teratol. 2015 Aug;103(8):733-40. doi: 10.1002/bdra.23373. Epub 2015 Apr 6.


Antibodies to GABAA receptor α1 and γ2 subunits: clinical and serologic characterization.

Pettingill P, Kramer HB, Coebergh JA, Pettingill R, Maxwell S, Nibber A, Malaspina A, Jacob A, Irani SR, Buckley C, Beeson D, Lang B, Waters P, Vincent A.

Neurology. 2015 Mar 24;84(12):1233-41. doi: 10.1212/WNL.0000000000001326. Epub 2015 Jan 30.


Alterations in the anandamide metabolism in the development of neuropathic pain.

Malek N, Kucharczyk M, Starowicz K.

Biomed Res Int. 2014;2014:686908. doi: 10.1155/2014/686908. Epub 2014 Sep 2.


The riluzole derivative 2-amino-6-trifluoromethylthio-benzothiazole (SKA-19), a mixed KCa2 activator and NaV blocker, is a potent novel anticonvulsant.

Coleman N, Nguyen HM, Cao Z, Brown BM, Jenkins DP, Zolkowska D, Chen YJ, Tanaka BS, Goldin AL, Rogawski MA, Pessah IN, Wulff H.

Neurotherapeutics. 2015 Jan;12(1):234-49. doi: 10.1007/s13311-014-0305-y.


Depression and anxiety in people with epilepsy.

Kwon OY, Park SP.

J Clin Neurol. 2014 Jul;10(3):175-88. doi: 10.3988/jcn.2014.10.3.175. Epub 2014 Jul 3. Review. Erratum in: J Clin Neurol. 2014 Oct;10(4):375.


Convulsive liability of cefepime and meropenem in normal and corneal kindled mice.

Tanaka A, Takechi K, Watanabe S, Tanaka M, Suemaru K, Araki H.

Antimicrob Agents Chemother. 2014 Aug;58(8):4380-3. doi: 10.1128/AAC.02862-14. Epub 2014 May 19.

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