Cited In for PMID: 15225702

Year	Number of Results
2004	1
2005	2
2007	2
2008	1
2009	1
2010	1
2011	1
2012	2
2014	1
2016	3
2017	2
2020	2
2021	1
2023	1
2024	0

1

Definition of the heterocyclic pharmacophore of bacterial methionyl tRNA synthetase inhibitors: potent antibacterially active non-quinolone analogues.

Jarvest RL, Armstrong SA, Berge JM, Brown P, Elder JS, Brown MJ, Copley RC, Forrest AK, Hamprecht DW, O'Hanlon PJ, Mitchell DJ, Rittenhouse S, Witty DR. Jarvest RL, et al. Bioorg Med Chem Lett. 2004 Aug 2;14(15):3937-41. doi: 10.1016/j.bmcl.2004.05.070. Bioorg Med Chem Lett. 2004. PMID: 15225702

2

Exploring Proteus mirabilis Methionine tRNA Synthetase Active Site: Homology Model Construction, Molecular Dynamics, Pharmacophore and Docking Validation.

Elbaramawi SS, Eissa AG, Noureldin NA, Simons C. Elbaramawi SS, et al. Pharmaceuticals (Basel). 2023 Sep 6;16(9):1263. doi: 10.3390/ph16091263. Pharmaceuticals (Basel). 2023. PMID: 37765071 Free PMC article.

3

Molecular basis for diaryldiamine selectivity and competition with tRNA in a type 2 methionyl-tRNA synthetase from a Gram-negative bacterium.

Mercaldi GF, Andrade MO, Zanella JL, Cordeiro AT, Benedetti CE. Mercaldi GF, et al. J Biol Chem. 2021 Jan-Jun;296:100658. doi: 10.1016/j.jbc.2021.100658. Epub 2021 Apr 12. J Biol Chem. 2021. PMID: 33857480 Free PMC article.

4

Structure-guided discovery of selective methionyl-tRNA synthetase inhibitors with potent activity against Trypanosoma brucei.

Zhang Z, Barros-Álvarez X, Gillespie JR, Ranade RM, Huang W, Shibata S, Molasky NMR, Faghih O, Mushtaq A, Choy RKM, de Hostos E, Hol WGJ, Verlinde CLMJ, Buckner FS, Fan E. Zhang Z, et al. RSC Med Chem. 2020 May 18;11(8):885-895. doi: 10.1039/d0md00057d. eCollection 2020 Aug 1. RSC Med Chem. 2020. PMID: 33479683 Free PMC article.

5

One-Pot Multicomponent Synthesis and Bioevaluation of Tetrahydroquinoline Derivatives as Potential Antioxidants, α-Amylase Enzyme Inhibitors, Anti-Cancerous and Anti-Inflammatory Agents.

Farooq S, Mazhar A, Ghouri A, Ihsan-Ul-Haq, Ullah N. Farooq S, et al. Molecules. 2020 Jun 11;25(11):2710. doi: 10.3390/molecules25112710. Molecules. 2020. PMID: 32545290 Free PMC article.

6

Development of Methionyl-tRNA Synthetase Inhibitors as Antibiotics for Gram-Positive Bacterial Infections.

Faghih O, Zhang Z, Ranade RM, Gillespie JR, Creason SA, Huang W, Shibata S, Barros-Álvarez X, Verlinde CLMJ, Hol WGJ, Fan E, Buckner FS. Faghih O, et al. Antimicrob Agents Chemother. 2017 Oct 24;61(11):e00999-17. doi: 10.1128/AAC.00999-17. Print 2017 Nov. Antimicrob Agents Chemother. 2017. PMID: 28848016 Free PMC article.

7

Optimization of a binding fragment targeting the "enlarged methionine pocket" leads to potent Trypanosoma brucei methionyl-tRNA synthetase inhibitors.

Huang W, Zhang Z, Ranade RM, Gillespie JR, Barros-Álvarez X, Creason SA, Shibata S, Verlinde CLMJ, Hol WGJ, Buckner FS, Fan E. Huang W, et al. Bioorg Med Chem Lett. 2017 Jun 15;27(12):2702-2707. doi: 10.1016/j.bmcl.2017.04.048. Epub 2017 Apr 17. Bioorg Med Chem Lett. 2017. PMID: 28465105 Free PMC article.

8

Structure-guided design of novel Trypanosoma brucei Methionyl-tRNA synthetase inhibitors.

Huang W, Zhang Z, Barros-Álvarez X, Koh CY, Ranade RM, Gillespie JR, Creason SA, Shibata S, Verlinde CLMJ, Hol WGJ, Buckner FS, Fan E. Huang W, et al. Eur J Med Chem. 2016 Nov 29;124:1081-1092. doi: 10.1016/j.ejmech.2016.10.024. Epub 2016 Oct 14. Eur J Med Chem. 2016. PMID: 27788467 Free PMC article.

9

5-Fluoroimidazo[4,5-b]pyridine Is a Privileged Fragment That Conveys Bioavailability to Potent Trypanosomal Methionyl-tRNA Synthetase Inhibitors.

Zhang Z, Koh CY, Ranade RM, Shibata S, Gillespie JR, Hulverson MA, Huang W, Nguyen J, Pendem N, Gelb MH, Verlinde CL, Hol WG, Buckner FS, Fan E. Zhang Z, et al. ACS Infect Dis. 2016 Jun 10;2(6):399-404. doi: 10.1021/acsinfecdis.6b00036. Epub 2016 Apr 11. ACS Infect Dis. 2016. PMID: 27627628 Free PMC article.

10

Synthesis and fungicidal activity of pyrazole derivatives containing 1,2,3,4-tetrahydroquinoline.

Lei P, Zhang X, Xu Y, Xu G, Liu X, Yang X, Zhang X, Ling Y. Lei P, et al. Chem Cent J. 2016 Jul 4;10:40. doi: 10.1186/s13065-016-0186-8. eCollection 2016. Chem Cent J. 2016. PMID: 27382411 Free PMC article.

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