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FRET binding antenna reports spatiotemporal dynamics of GDI-Cdc42 GTPase interactions.

Hodgson L, Spiering D, Sabouri-Ghomi M, Dagliyan O, DerMardirossian C, Danuser G, Hahn KM.

Nat Chem Biol. 2016 Oct;12(10):802-9. doi: 10.1038/nchembio.2145.


p21-activated kinase 2 regulates HSPC cytoskeleton, migration, and homing via CDC42 activation and interaction with β-Pix.

Reddy PN, Radu M, Xu K, Wood J, Harris CE, Chernoff J, Williams DA.

Blood. 2016 Apr 21;127(16):1967-75. doi: 10.1182/blood-2016-01-693572.


The Role of Rac1 in the Growth Cone Dynamics and Force Generation of DRG Neurons.

Sayyad WA, Fabris P, Torre V.

PLoS One. 2016 Jan 14;11(1):e0146842. doi: 10.1371/journal.pone.0146842.


Structural and Mechanistic Insights into the Regulation of the Fundamental Rho Regulator RhoGDIα by Lysine Acetylation.

Kuhlmann N, Wroblowski S, Knyphausen P, de Boor S, Brenig J, Zienert AY, Meyer-Teschendorf K, Praefcke GJ, Nolte H, Krüger M, Schacherl M, Baumann U, James LC, Chin JW, Lammers M.

J Biol Chem. 2016 Mar 11;291(11):5484-99. doi: 10.1074/jbc.M115.707091.


Regulation of Macropinocytosis by Diacylglycerol Kinase ζ.

Ard R, Mulatz K, Pomoransky JL, Parks RJ, Trinkle-Mulcahy L, Bell JC, Gee SH.

PLoS One. 2015 Dec 23;10(12):e0144942. doi: 10.1371/journal.pone.0144942.


Kinases Mst1 and Mst2 positively regulate phagocytic induction of reactive oxygen species and bactericidal activity.

Geng J, Sun X, Wang P, Zhang S, Wang X, Wu H, Hong L, Xie C, Li X, Zhao H, Liu Q, Jiang M, Chen Q, Zhang J, Li Y, Song S, Wang HR, Zhou R, Johnson RL, Chien KY, Lin SC, Han J, Avruch J, Chen L, Zhou D.

Nat Immunol. 2015 Nov;16(11):1142-52. doi: 10.1038/ni.3268.


Positive regulation of Rho GTPase activity by RhoGDIs as a result of their direct interaction with GAPs.

Ota T, Maeda M, Okamoto M, Tatsuka M.

BMC Syst Biol. 2015 Jan 28;9:3. doi: 10.1186/s12918-015-0143-5.


ADP-ribosylation factor 6 (ARF6) bidirectionally regulates dendritic spine formation depending on neuronal maturation and activity.

Kim Y, Lee SE, Park J, Kim M, Lee B, Hwang D, Chang S.

J Biol Chem. 2015 Mar 20;290(12):7323-35. doi: 10.1074/jbc.M114.634527.


The cognitive defects of neonatally irradiated mice are accompanied by changed synaptic plasticity, adult neurogenesis and neuroinflammation.

Kempf SJ, Casciati A, Buratovic S, Janik D, von Toerne C, Ueffing M, Neff F, Moertl S, Stenerlöw B, Saran A, Atkinson MJ, Eriksson P, Pazzaglia S, Tapio S.

Mol Neurodegener. 2014 Dec 16;9:57. doi: 10.1186/1750-1326-9-57.


Signaling of the p21-activated kinase (PAK1) coordinates insulin-stimulated actin remodeling and glucose uptake in skeletal muscle cells.

Tunduguru R, Chiu TT, Ramalingam L, Elmendorf JS, Klip A, Thurmond DC.

Biochem Pharmacol. 2014 Nov 15;92(2):380-8. doi: 10.1016/j.bcp.2014.08.033.


14-3-3τ promotes breast cancer invasion and metastasis by inhibiting RhoGDIα.

Xiao Y, Lin VY, Ke S, Lin GE, Lin FT, Lin WC.

Mol Cell Biol. 2014 Jul;34(14):2635-49. Erratum in: Mol Cell Biol. 2014 Aug;34(16):3180.


Signaling mechanisms of glucose-induced F-actin remodeling in pancreatic islet β cells.

Kalwat MA, Thurmond DC.

Exp Mol Med. 2013 Aug 23;45:e37. doi: 10.1038/emm.2013.73. Review.


CPK3-phosphorylated RhoGDI1 is essential in the development of Arabidopsis seedlings and leaf epidermal cells.

Wu Y, Zhao S, Tian H, He Y, Xiong W, Guo L, Wu Y.

J Exp Bot. 2013 Aug;64(11):3327-38. doi: 10.1093/jxb/ert171.


Cholecystokinin-mediated RhoGDI phosphorylation via PKCα promotes both RhoA and Rac1 signaling.

Sabbatini ME, Williams JA.

PLoS One. 2013 Jun 11;8(6):e66029. doi: 10.1371/journal.pone.0066029.


Hold on tightly: how to keep the local activation of small GTPases.

Garcia-Cattaneo A, Braga VM.

Cell Adh Migr. 2013 May-Jun;7(3):283-7. doi: 10.4161/cam.24646.


Rictor encounters RhoGDI2: the second pilot is taking a lead.

Agarwal NK, Kazyken D, Sarbassov dos D.

Small GTPases. 2013 Apr-Jun;4(2):102-5. doi: 10.4161/sgtp.23346.


Computational analysis of Rho GTPase cycling.

Falkenberg CV, Loew LM.

PLoS Comput Biol. 2013;9(1):e1002831. doi: 10.1371/journal.pcbi.1002831.


PAK signaling in cancer.

Ye DZ, Field J.

Cell Logist. 2012 Apr 1;2(2):105-116.

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