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Items: 1 to 20 of 532


SIRT1-dependent modulation of methylation and acetylation of histone H3 on lysine 9 (H3K9) in the zygotic pronuclei improves porcine embryo development.

Adamkova K, Yi YJ, Petr J, Zalmanova T, Hoskova K, Jelinkova P, Moravec J, Kralickova M, Sutovsky M, Sutovsky P, Nevoral J.

J Anim Sci Biotechnol. 2017 Nov 1;8:83. doi: 10.1186/s40104-017-0214-0. eCollection 2017.


Alterations of sirtuins in mitochondrial cytochrome c-oxidase deficiency.

Potthast AB, Heuer T, Warneke SJ, Das AM.

PLoS One. 2017 Oct 23;12(10):e0186517. doi: 10.1371/journal.pone.0186517. eCollection 2017.


A comparative study of anti-aging properties and mechanism: resveratrol and caloric restriction.

Li J, Zhang CX, Liu YM, Chen KL, Chen G.

Oncotarget. 2017 Aug 9;8(39):65717-65729. doi: 10.18632/oncotarget.20084. eCollection 2017 Sep 12.


Potent mechanism-based sirtuin-2-selective inhibition by an in situ-generated occupant of the substrate-binding site, "selectivity pocket" and NAD+-binding site.

Mellini P, Itoh Y, Tsumoto H, Li Y, Suzuki M, Tokuda N, Kakizawa T, Miura Y, Takeuchi J, Lahtela-Kakkonen M, Suzuki T.

Chem Sci. 2017 Sep 1;8(9):6400-6408. doi: 10.1039/c7sc02738a. Epub 2017 Jul 21.


Targeting Mitochondrial Dysfunction for the Treatment of Diabetic Complications: Pharmacological Interventions through Natural Products.

Kaikini AA, Kanchan DM, Nerurkar UN, Sathaye S.

Pharmacogn Rev. 2017 Jul-Sep;11(22):128-135. doi: 10.4103/phrev.phrev_41_16. Review.


SIRT1 is a positive regulator of in vivo bone mass and a therapeutic target for osteoporosis.

Zainabadi K, Liu CJ, Caldwell ALM, Guarente L.

PLoS One. 2017 Sep 22;12(9):e0185236. doi: 10.1371/journal.pone.0185236. eCollection 2017.


SIRT1 gene polymorphisms and risk of lung cancer.

Lv Y, Lin S, Peng F.

Cancer Manag Res. 2017 Sep 4;9:381-386. doi: 10.2147/CMAR.S142677. eCollection 2017.


mTOR signaling promotes foam cell formation and inhibits foam cell egress through suppressing the SIRT1 signaling pathway.

Zheng H, Fu Y, Huang Y, Zheng X, Yu W, Wang W.

Mol Med Rep. 2017 Sep;16(3):3315-3323. doi: 10.3892/mmr.2017.7032. Epub 2017 Jul 18.


The Preconditioning of Berberine Suppresses Hydrogen Peroxide-Induced Premature Senescence via Regulation of Sirtuin 1.

Zhu X, Yue H, Guo X, Yang J, Liu J, Liu J, Wang R, Zhu W.

Oxid Med Cell Longev. 2017;2017:2391820. doi: 10.1155/2017/2391820. Epub 2017 Jul 2.


miR-34a and miR-9 are overexpressed and SIRT genes are downregulated in peripheral blood mononuclear cells of aging humans.

Owczarz M, Budzinska M, Domaszewska-Szostek A, Borkowska J, Polosak J, Gewartowska M, Slusarczyk P, Puzianowska-Kuznicka M.

Exp Biol Med (Maywood). 2017 Aug;242(14):1453-1461. doi: 10.1177/1535370217720884. Epub 2017 Jul 12.


Cardioprotective Effects of SIRT6 in a Mouse Model of Transverse Aortic Constriction-Induced Heart Failure.

Li Y, Meng X, Wang W, Liu F, Hao Z, Yang Y, Zhao J, Yin W, Xu L, Zhao R, Hu J.

Front Physiol. 2017 Jun 13;8:394. doi: 10.3389/fphys.2017.00394. eCollection 2017.


Reduction in podocyte SIRT1 accelerates kidney injury in aging mice.

Chuang PY, Cai W, Li X, Fang L, Xu J, Yacoub R, He JC, Lee K.

Am J Physiol Renal Physiol. 2017 Sep 1;313(3):F621-F628. doi: 10.1152/ajprenal.00255.2017. Epub 2017 Jun 14.


Meat Intake and the Dose of Vitamin B3 - Nicotinamide: Cause of the Causes of Disease Transitions, Health Divides, and Health Futures?

Hill LJ, Williams AC.

Int J Tryptophan Res. 2017 May 3;10:1178646917704662. doi: 10.1177/1178646917704662. eCollection 2017. Review.


USP22 Induces Cisplatin Resistance in Lung Adenocarcinoma by Regulating γH2AX-Mediated DNA Damage Repair and Ku70/Bax-Mediated Apoptosis.

Wang A, Ning Z, Lu C, Gao W, Liang J, Yan Q, Tan G, Liu J.

Front Pharmacol. 2017 May 17;8:274. doi: 10.3389/fphar.2017.00274. eCollection 2017.


Effect of dietary restriction and subsequent re-alimentation on the transcriptional profile of bovine ruminal epithelium.

Keogh K, Waters SM, Cormican P, Kelly AK, O'Shea E, Kenny DA.

PLoS One. 2017 May 17;12(5):e0177852. doi: 10.1371/journal.pone.0177852. eCollection 2017.


Association of FGFR2 rs2981582, SIRT1 rs12778366, STAT3 rs744166 gene polymorphisms with pituitary adenoma.

Glebauskiene B, Vilkeviciute A, Liutkeviciene R, Jakstiene S, Kriauciuniene L, Zemaitiene R, Zaliuniene D.

Oncol Lett. 2017 May;13(5):3087-3099. doi: 10.3892/ol.2017.5840. Epub 2017 Mar 10.


Mitochondrial determinants of cancer health disparities.

Choudhury AR, Singh KK.

Semin Cancer Biol. 2017 May 6. pii: S1044-579X(17)30122-0. doi: 10.1016/j.semcancer.2017.05.001. [Epub ahead of print] Review.


Mitochondrial Control and Guidance of Cellular Activities of T Cells.

Chao T, Wang H, Ho PC.

Front Immunol. 2017 Apr 24;8:473. doi: 10.3389/fimmu.2017.00473. eCollection 2017. Review.


Energy sensing pathways: Bridging type 2 diabetes and colorectal cancer?

Yang J, Nishihara R, Zhang X, Ogino S, Qian ZR.

J Diabetes Complications. 2017 Jul;31(7):1228-1236. doi: 10.1016/j.jdiacomp.2017.04.012. Epub 2017 Apr 13. Review.


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