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Items: 1 to 20 of 138


Alterations in Gene Expression of Components of the Renin-Angiotensin System and Its Related Enzymes in Lung Cancer.

Goldstein B, Trivedi M, Speth RC.

Lung Cancer Int. 2017;2017:6914976. doi: 10.1155/2017/6914976. Epub 2017 Jul 16.


The Diverse Roles of Arrestin Scaffolds in G Protein-Coupled Receptor Signaling.

Peterson YK, Luttrell LM.

Pharmacol Rev. 2017 Jul;69(3):256-297. doi: 10.1124/pr.116.013367. Review.


Regulation of G Protein-Coupled Receptors by Ubiquitination.

Skieterska K, Rondou P, Van Craenenbroeck K.

Int J Mol Sci. 2017 Apr 27;18(5). pii: E923. doi: 10.3390/ijms18050923. Review.


β2-Adrenergic receptor activation mobilizes intracellular calcium via a non-canonical cAMP-independent signaling pathway.

Galaz-Montoya M, Wright SJ, Rodriguez GJ, Lichtarge O, Wensel TG.

J Biol Chem. 2017 Jun 16;292(24):9967-9974. doi: 10.1074/jbc.M117.787119. Epub 2017 Apr 25.


Angiotensin II activates CaV 1.2 Ca2+ channels through β-arrestin2 and casein kinase 2 in mouse immature cardiomyocytes.

Kashihara T, Nakada T, Kojima K, Takeshita T, Yamada M.

J Physiol. 2017 Jul 1;595(13):4207-4225. doi: 10.1113/JP273883. Epub 2017 Apr 20.


Sex-biased cellular signaling: molecular basis for sex differences in neuropsychiatric diseases.

Valentino RJ, Bangasser DA.

Dialogues Clin Neurosci. 2016 Dec;18(4):385-393.


Phosphorylation of β-arrestin2 at Thr383 by MEK underlies β-arrestin-dependent activation of Erk1/2 by GPCRs.

Cassier E, Gallay N, Bourquard T, Claeysen S, Bockaert J, Crépieux P, Poupon A, Reiter E, Marin P, Vandermoere F.

Elife. 2017 Feb 7;6. pii: e23777. doi: 10.7554/eLife.23777.


Angiotensin Converting Enzyme Regulates Cell Proliferation and Migration.

Alvarenga EC, Fonseca MC, Carvalho CC, Florentino RM, França A, Matias E, Guimarães PB, Batista C, Freire V, Carmona AK, Pesquero JB, de Paula AM, Foureaux G, Leite MF.

PLoS One. 2016 Dec 19;11(12):e0165371. doi: 10.1371/journal.pone.0165371. eCollection 2016.


Functional competence of a partially engaged GPCR-β-arrestin complex.

Kumari P, Srivastava A, Banerjee R, Ghosh E, Gupta P, Ranjan R, Chen X, Gupta B, Gupta C, Jaiman D, Shukla AK.

Nat Commun. 2016 Nov 9;7:13416. doi: 10.1038/ncomms13416.


Immunomodulatory Effects Mediated by Dopamine.

Arreola R, Alvarez-Herrera S, Pérez-Sánchez G, Becerril-Villanueva E, Cruz-Fuentes C, Flores-Gutierrez EO, Garcés-Alvarez ME, de la Cruz-Aguilera DL, Medina-Rivero E, Hurtado-Alvarado G, Quintero-Fabián S, Pavón L.

J Immunol Res. 2016;2016:3160486. Epub 2016 Oct 4. Review.


Molecular signatures of mu opioid receptor and somatostatin receptor 2 in pancreatic cancer.

Jorand R, Biswas S, Wakefield DL, Tobin SJ, Golfetto O, Hilton K, Ko M, Ramos JW, Small AR, Chu P, Singh G, Jovanovic-Talisman T.

Mol Biol Cell. 2016 Nov 7;27(22):3659-3672. Epub 2016 Sep 28.


Long-Term Reduction of Kappa Opioid Receptor Function by the Biased Ligand, Norbinaltorphimine, Requires c-Jun N-Terminal Kinase Activity and New Protein Synthesis in Peripheral Sensory Neurons.

Jamshidi RJ, Sullivan LC, Jacobs BA, Chavera TA, Berg KA, Clarke WP.

J Pharmacol Exp Ther. 2016 Nov;359(2):319-328. Epub 2016 Sep 7.


Agonist-induced internalization and desensitization of the apelin receptor.

Pope GR, Tilve S, McArdle CA, Lolait SJ, O'Carroll AM.

Mol Cell Endocrinol. 2016 Dec 5;437:108-119. doi: 10.1016/j.mce.2016.07.040. Epub 2016 Aug 1.


Multi-Compartmentalisation in the MAPK Signalling Pathway Contributes to the Emergence of Oscillatory Behaviour and to Ultrasensitivity.

Shuaib A, Hartwell A, Kiss-Toth E, Holcombe M.

PLoS One. 2016 May 31;11(5):e0156139. doi: 10.1371/journal.pone.0156139. eCollection 2016.


Angiotensin II receptors and peritoneal dialysis-induced peritoneal fibrosis.

Morinelli TA, Luttrell LM, Strungs EG, Ullian ME.

Int J Biochem Cell Biol. 2016 Aug;77(Pt B):240-50. doi: 10.1016/j.biocel.2016.04.016. Epub 2016 May 7.


Roles of Dopamine D₂ Receptor Subregions in Interactions with β-Arrestin2.

Zhang X, Choi BG, Kim KM.

Biomol Ther (Seoul). 2016 Sep 1;24(5):517-22. doi: 10.4062/biomolther.2015.198.


The role of kinetic context in apparent biased agonism at GPCRs.

Klein Herenbrink C, Sykes DA, Donthamsetti P, Canals M, Coudrat T, Shonberg J, Scammells PJ, Capuano B, Sexton PM, Charlton SJ, Javitch JA, Christopoulos A, Lane JR.

Nat Commun. 2016 Feb 24;7:10842. doi: 10.1038/ncomms10842.


Practical Strategies and Concepts in GPCR Allosteric Modulator Discovery: Recent Advances with Metabotropic Glutamate Receptors.

Lindsley CW, Emmitte KA, Hopkins CR, Bridges TM, Gregory KJ, Niswender CM, Conn PJ.

Chem Rev. 2016 Jun 8;116(11):6707-41. doi: 10.1021/acs.chemrev.5b00656. Epub 2016 Feb 16. Review.


β-Arrestin drives MAP kinase signalling from clathrin-coated structures after GPCR dissociation.

Eichel K, Jullié D, von Zastrow M.

Nat Cell Biol. 2016 Mar;18(3):303-10. doi: 10.1038/ncb3307. Epub 2016 Feb 1.


Regulation of N-Formyl Peptide Receptor Signaling and Trafficking by Arrestin-Src Kinase Interaction.

Wagener BM, Marjon NA, Prossnitz ER.

PLoS One. 2016 Jan 20;11(1):e0147442. doi: 10.1371/journal.pone.0147442. eCollection 2016.

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