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An update on migraine: current understanding and future directions.

Puledda F, Messina R, Goadsby PJ.

J Neurol. 2017 Sep;264(9):2031-2039. doi: 10.1007/s00415-017-8434-y. Epub 2017 Mar 20.


Neto2 Assembles with Kainate Receptors in DRG Neurons during Development and Modulates Neurite Outgrowth in Adult Sensory Neurons.

Vernon CG, Swanson GT.

J Neurosci. 2017 Mar 22;37(12):3352-3363. doi: 10.1523/JNEUROSCI.2978-16.2017. Epub 2017 Feb 24.


Pathophysiology of Migraine: A Disorder of Sensory Processing.

Goadsby PJ, Holland PR, Martins-Oliveira M, Hoffmann J, Schankin C, Akerman S.

Physiol Rev. 2017 Apr;97(2):553-622. doi: 10.1152/physrev.00034.2015. Review.


Metabotropic glutamate receptor 5: a target for migraine therapy.

Waung MW, Akerman S, Wakefield M, Keywood C, Goadsby PJ.

Ann Clin Transl Neurol. 2016 Jul 1;3(8):560-71. doi: 10.1002/acn3.302. eCollection 2016 Aug.


Release of CGRP from mouse brainstem slices indicates central inhibitory effect of triptans and kynurenate.

Kageneck C, Nixdorf-Bergweiler BE, Messlinger K, Fischer MJ.

J Headache Pain. 2014 Feb 8;15:7. doi: 10.1186/1129-2377-15-7.


Receptor and channel heteromers as pain targets.

Berg KA, Patwardhan AM, Akopian AN.

Pharmaceuticals (Basel). 2012 Feb 23;5(3):249-78. doi: 10.3390/ph5030249.


Kainate receptor signaling in pain pathways.

Bhangoo SK, Swanson GT.

Mol Pharmacol. 2013 Feb;83(2):307-15. doi: 10.1124/mol.112.081398. Epub 2012 Oct 24. Review.


Efficacy of the GluK1/AMPA receptor antagonist LY293558 against seizures and neuropathology in a soman-exposure model without pretreatment and its pharmacokinetics after intramuscular administration.

Apland JP, Aroniadou-Anderjaska V, Figueiredo TH, Green CE, Swezey R, Yang C, Qashu F, Braga MF.

J Pharmacol Exp Ther. 2013 Jan;344(1):133-40. doi: 10.1124/jpet.112.198689. Epub 2012 Oct 5.


Pathophysiology of migraine.

Goadsby PJ.

Ann Indian Acad Neurol. 2012 Aug;15(Suppl 1):S15-22.


Presynaptic facilitation of glutamate release in the basolateral amygdala: a mechanism for the anxiogenic and seizurogenic function of GluK1 receptors.

Aroniadou-Anderjaska V, Pidoplichko VI, Figueiredo TH, Almeida-Suhett CP, Prager EM, Braga MF.

Neuroscience. 2012 Sep 27;221:157-69. doi: 10.1016/j.neuroscience.2012.07.006. Epub 2012 Jul 13.


Medicinal chemistry of competitive kainate receptor antagonists.

Larsen AM, Bunch L.

ACS Chem Neurosci. 2011 Feb 16;2(2):60-74. doi: 10.1021/cn1001039. Epub 2010 Dec 10. Review.


Sumatriptan (subcutaneous route of administration) for acute migraine attacks in adults.

Derry CJ, Derry S, Moore RA.

Cochrane Database Syst Rev. 2012 Feb 15;(2):CD009665. doi: 10.1002/14651858.CD009665. Review.


Kynurenine metabolites and migraine: experimental studies and therapeutic perspectives.

Fejes A, Párdutz A, Toldi J, Vécsei L.

Curr Neuropharmacol. 2011 Jun;9(2):376-87. doi: 10.2174/157015911795596621.


Calcitonin gene-related peptide in migraine: intersection of peripheral inflammation and central modulation.

Raddant AC, Russo AF.

Expert Rev Mol Med. 2011 Nov 29;13:e36. doi: 10.1017/S1462399411002067. Review.


Acute migraine therapy: new drugs and new approaches.

Monteith TS, Goadsby PJ.

Curr Treat Options Neurol. 2011 Feb;13(1):1-14. doi: 10.1007/s11940-010-0105-6.


Suppression of stretch reflex activity after spinal or systemic treatment with AMPA receptor antagonist NGX424 in rats with developed baclofen tolerance.

Oshiro M, Hefferan MP, Kakinohana O, Lukacova N, Sugahara K, Yaksh TL, Marsala M.

Br J Pharmacol. 2010 Nov;161(5):976-85. doi: 10.1111/j.1476-5381.2010.00954.x.


The GluK1 (GluR5) Kainate/{alpha}-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor antagonist LY293558 reduces soman-induced seizures and neuropathology.

Figueiredo TH, Qashu F, Apland JP, Aroniadou-Anderjaska V, Souza AP, Braga MF.

J Pharmacol Exp Ther. 2011 Feb;336(2):303-12. doi: 10.1124/jpet.110.171835. Epub 2010 Oct 20.


Are the current IHS guidelines for migraine drug trials being followed?

Hougaard A, Tfelt-Hansen P.

J Headache Pain. 2010 Dec;11(6):457-68. doi: 10.1007/s10194-010-0257-5. Epub 2010 Oct 8. Review.


Glutamate receptor ion channels: structure, regulation, and function.

Traynelis SF, Wollmuth LP, McBain CJ, Menniti FS, Vance KM, Ogden KK, Hansen KB, Yuan H, Myers SJ, Dingledine R.

Pharmacol Rev. 2010 Sep;62(3):405-96. doi: 10.1124/pr.109.002451. Review. Erratum in: Pharmacol Rev. 2014 Oct;66(4):1141.


Effects of ionotropic glutamate receptor antagonists on rat dural artery diameter in an intravital microscopy model.

Chan KY, Gupta S, de Vries R, Danser AH, Villalón CM, Muñoz-Islas E, Maassenvandenbrink A.

Br J Pharmacol. 2010 Jul;160(6):1316-25. doi: 10.1111/j.1476-5381.2010.00733.x.

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