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Items: 20


Proteasome stress sensitizes malignant pleural mesothelioma cells to bortezomib-induced apoptosis.

Cerruti F, Jocollè G, Salio C, Oliva L, Paglietti L, Alessandria B, Mioletti S, Donati G, Numico G, Cenci S, Cascio P.

Sci Rep. 2017 Dec 15;7(1):17626. doi: 10.1038/s41598-017-17977-9.


The life cycle of the 26S proteasome: from birth, through regulation and function, and onto its death.

Livneh I, Cohen-Kaplan V, Cohen-Rosenzweig C, Avni N, Ciechanover A.

Cell Res. 2016 Aug;26(8):869-85. doi: 10.1038/cr.2016.86. Epub 2016 Jul 22. Review.


Expression of three topologically distinct membrane proteins elicits unique stress response pathways in the yeast Saccharomyces cerevisiae.

Buck TM, Jordan R, Lyons-Weiler J, Adelman JL, Needham PG, Kleyman TR, Brodsky JL.

Physiol Genomics. 2015 Jun;47(6):198-214. doi: 10.1152/physiolgenomics.00101.2014. Epub 2015 Mar 10.


Yeast Pah1p phosphatidate phosphatase is regulated by proteasome-mediated degradation.

Pascual F, Hsieh LS, Soto-Cardalda A, Carman GM.

J Biol Chem. 2014 Apr 4;289(14):9811-22. doi: 10.1074/jbc.M114.550103. Epub 2014 Feb 21.


Cdc48 chaperone and adaptor Ubx4 distribute the proteasome in the nucleus for anaphase proteolysis.

Chien CY, Chen RH.

J Biol Chem. 2013 Dec 27;288(52):37180-91. doi: 10.1074/jbc.M113.513598. Epub 2013 Nov 13.


The 26S proteasome drives trinucleotide repeat expansions.

Concannon C, Lahue RS.

Nucleic Acids Res. 2013 Jul;41(12):6098-108. doi: 10.1093/nar/gkt295. Epub 2013 Apr 24.


Translational infidelity-induced protein stress results from a deficiency in Trm9-catalyzed tRNA modifications.

Patil A, Chan CT, Dyavaiah M, Rooney JP, Dedon PC, Begley TJ.

RNA Biol. 2012 Jul;9(7):990-1001. doi: 10.4161/rna.20531. Epub 2012 Jul 1.


A network of ubiquitin ligases is important for the dynamics of misfolded protein aggregates in yeast.

Theodoraki MA, Nillegoda NB, Saini J, Caplan AJ.

J Biol Chem. 2012 Jul 6;287(28):23911-22. doi: 10.1074/jbc.M112.341164. Epub 2012 May 16.


Structural defects in the regulatory particle-core particle interface of the proteasome induce a novel proteasome stress response.

Park S, Kim W, Tian G, Gygi SP, Finley D.

J Biol Chem. 2011 Oct 21;286(42):36652-66. doi: 10.1074/jbc.M111.285924. Epub 2011 Aug 30.


Yeast biological networks unfold the interplay of antioxidants, genome and phenotype, and reveal a novel regulator of the oxidative stress response.

Otero JM, Papadakis MA, Udatha DB, Nielsen J, Panagiotou G.

PLoS One. 2010 Oct 25;5(10):e13606. doi: 10.1371/journal.pone.0013606.


Inhibition of proteasomal degradation of rpn4 impairs nonhomologous end-joining repair of DNA double-strand breaks.

Ju D, Wang X, Ha SW, Fu J, Xie Y.

PLoS One. 2010 Apr 1;5(4):e9877. doi: 10.1371/journal.pone.0009877.


Proteasomal degradation of Rpn4 in Saccharomyces cerevisiae is critical for cell viability under stressed conditions.

Wang X, Xu H, Ha SW, Ju D, Xie Y.

Genetics. 2010 Feb;184(2):335-42. doi: 10.1534/genetics.109.112227. Epub 2009 Nov 23.


Tandem affinity purification and mass spectrometric analysis of ubiquitylated proteins in Arabidopsis.

Saracco SA, Hansson M, Scalf M, Walker JM, Smith LM, Vierstra RD.

Plant J. 2009 Jul;59(2):344-58. doi: 10.1111/j.1365-313X.2009.03862.x. Epub 2009 Mar 9.


Analysis of quality control substrates in distinct cellular compartments reveals a unique role for Rpn4p in tolerating misfolded membrane proteins.

Metzger MB, Michaelis S.

Mol Biol Cell. 2009 Feb;20(3):1006-19. doi: 10.1091/mbc.E08-02-0140. Epub 2008 Dec 10.


Blm10 binds to pre-activated proteasome core particles with open gate conformation.

Lehmann A, Jechow K, Enenkel C.

EMBO Rep. 2008 Dec;9(12):1237-43. doi: 10.1038/embor.2008.190. Epub 2008 Oct 17. Erratum in: EMBO Rep. 2009 Jan;10(1):101.


Disruption of Rpn4-induced proteasome expression in Saccharomyces cerevisiae reduces cell viability under stressed conditions.

Wang X, Xu H, Ju D, Xie Y.

Genetics. 2008 Dec;180(4):1945-53. doi: 10.1534/genetics.108.094524. Epub 2008 Oct 1.


Genome-wide analysis identifies MYND-domain protein Mub1 as an essential factor for Rpn4 ubiquitylation.

Ju D, Wang X, Xu H, Xie Y.

Mol Cell Biol. 2008 Feb;28(4):1404-12. Epub 2007 Dec 10.


A proteasome for all occasions.

Hanna J, Finley D.

FEBS Lett. 2007 Jun 19;581(15):2854-61. Epub 2007 Mar 30. Review.


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