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Items: 1 to 20 of 62

1.

Mutations Driving Airborne Transmission of A/H5N1 Virus in Mammals Cause Substantial Attenuation in Chickens only when combined.

Richard M, Herfst S, van den Brand JMA, de Meulder D, Lexmond P, Bestebroer TM, Fouchier RAM.

Sci Rep. 2017 Aug 3;7(1):7187. doi: 10.1038/s41598-017-07000-6.

2.

Subtype-specific structural constraints in the evolution of influenza A virus hemagglutinin genes.

Gultyaev AP, Spronken MI, Richard M, Schrauwen EJ, Olsthoorn RC, Fouchier RA.

Sci Rep. 2016 Dec 14;6:38892. doi: 10.1038/srep38892.

3.

Preclinical evaluation of the safety and pathogenicity of a live attenuated recombinant influenza A/H7N9 seed strain and corresponding MF59-adjuvanted split vaccine.

Ou H, Yao W, Wu N, Wang FX, Weng T, Han C, Lu X, Yu D, Wu H, Cheng L, Chen H, Yao H, Li L.

Oncotarget. 2016 Dec 6;7(49):81012-81025. doi: 10.18632/oncotarget.12746.

4.

Role of the B Allele of Influenza A Virus Segment 8 in Setting Mammalian Host Range and Pathogenicity.

Turnbull ML, Wise HM, Nicol MQ, Smith N, Dunfee RL, Beard PM, Jagger BW, Ligertwood Y, Hardisty GR, Xiao H, Benton DJ, Coburn AM, Paulo JA, Gygi SP, McCauley JW, Taubenberger JK, Lycett SJ, Weekes MP, Dutia BM, Digard P.

J Virol. 2016 Sep 29;90(20):9263-84. doi: 10.1128/JVI.01205-16. Print 2016 Oct 15.

5.

Elevation of CpG frequencies in influenza A genome attenuates pathogenicity but enhances host response to infection.

Gaunt E, Wise HM, Zhang H, Lee LN, Atkinson NJ, Nicol MQ, Highton AJ, Klenerman P, Beard PM, Dutia BM, Digard P, Simmonds P.

Elife. 2016 Feb 16;5:e12735. doi: 10.7554/eLife.12735.

6.

Amino Acid Substitutions That Affect Receptor Binding and Stability of the Hemagglutinin of Influenza A/H7N9 Virus.

Schrauwen EJ, Richard M, Burke DF, Rimmelzwaan GF, Herfst S, Fouchier RA.

J Virol. 2016 Jan 20;90(7):3794-9. doi: 10.1128/JVI.03052-15.

7.

Seroprevalence of Antibodies against Seal Influenza A(H10N7) Virus in Harbor Seals and Gray Seals from the Netherlands.

Bodewes R, Rubio García A, Brasseur SM, Sanchez Conteras GJ, van de Bildt MW, Koopmans MP, Osterhaus AD, Kuiken T.

PLoS One. 2015 Dec 14;10(12):e0144899. doi: 10.1371/journal.pone.0144899. eCollection 2015.

8.

Differential Recognition of Influenza A Viruses by M158-66 Epitope-Specific CD8+ T Cells Is Determined by Extraepitopic Amino Acid Residues.

van de Sandt CE, Kreijtz JH, Geelhoed-Mieras MM, Nieuwkoop NJ, Spronken MI, van de Vijver DA, Fouchier RA, Osterhaus AD, Rimmelzwaan GF.

J Virol. 2015 Nov 4;90(2):1009-22. doi: 10.1128/JVI.02439-15.

9.

Optimisations and Challenges Involved in the Creation of Various Bioluminescent and Fluorescent Influenza A Virus Strains for In Vitro and In Vivo Applications.

Spronken MI, Short KR, Herfst S, Bestebroer TM, Vaes VP, van der Hoeven B, Koster AJ, Kremers GJ, Scott DP, Gultyaev AP, Sorell EM, de Graaf M, Bárcena M, Rimmelzwaan GF, Fouchier RA.

PLoS One. 2015 Aug 4;10(8):e0133888. doi: 10.1371/journal.pone.0133888. eCollection 2015.

10.

Establishment of a High-Throughput Assay to Monitor Influenza A Virus RNA Transcription and Replication.

Wang Z, Zhao F, Gao Q, Liu Z, Zhang Y, Li X, Li Y, Ma W, Deng T, Zhang Z, Cen S.

PLoS One. 2015 Jul 21;10(7):e0133558. doi: 10.1371/journal.pone.0133558. eCollection 2015.

11.

Recombinant Immunomodulating Lentogenic or Mesogenic Oncolytic Newcastle Disease Virus for Treatment of Pancreatic Adenocarcinoma.

Buijs P, van Nieuwkoop S, Vaes V, Fouchier R, van Eijck C, van den Hoogen B.

Viruses. 2015 Jun 11;7(6):2980-98. doi: 10.3390/v7062756.

12.

Analysis of the genetic diversity of influenza A viruses using next-generation DNA sequencing.

Van den Hoecke S, Verhelst J, Vuylsteke M, Saelens X.

BMC Genomics. 2015 Feb 14;16:79. doi: 10.1186/s12864-015-1284-z.

13.

Optimization of an enzyme-linked lectin assay suitable for rapid antigenic characterization of the neuraminidase of human influenza A(H3N2) viruses.

Westgeest KB, Bestebroer TM, Spronken MI, Gao J, Couzens L, Osterhaus AD, Eichelberger M, Fouchier RA, de Graaf M.

J Virol Methods. 2015 Jun 1;217:55-63. doi: 10.1016/j.jviromet.2015.02.014. Epub 2015 Feb 21.

14.

Identification of amino acid substitutions supporting antigenic change of influenza A(H1N1)pdm09 viruses.

Koel BF, Mögling R, Chutinimitkul S, Fraaij PL, Burke DF, van der Vliet S, de Wit E, Bestebroer TM, Rimmelzwaan GF, Osterhaus AD, Smith DJ, Fouchier RA, de Graaf M.

J Virol. 2015 Apr;89(7):3763-75. doi: 10.1128/JVI.02962-14. Epub 2015 Jan 21.

15.

An efficient genome sequencing method for equine influenza [H3N8] virus reveals a new polymorphism in the PA-X protein.

Rash A, Woodward A, Bryant N, McCauley J, Elton D.

Virol J. 2014 Sep 2;11:159. doi: 10.1186/1743-422X-11-159.

16.

RNA structural constraints in the evolution of the influenza A virus genome NP segment.

Gultyaev AP, Tsyganov-Bodounov A, Spronken MI, van der Kooij S, Fouchier RA, Olsthoorn RC.

RNA Biol. 2014;11(7):942-52. doi: 10.4161/rna.29730. Epub 2014 Jul 23.

17.

Protective immunity and safety of a genetically modified influenza virus vaccine.

Barbosa RP, Salgado AP, Garcia CC, Filho BG, Gonçalves AP, Lima BH, Lopes GA, Rachid MA, Peixoto AC, de Oliveira DB, Ataíde MA, Zirke CA, Cotrim TM, Costa ÉA, Almeida GM, Russo RC, Gazzinelli RT, Machado Ade M.

PLoS One. 2014 Jun 13;9(6):e98685. doi: 10.1371/journal.pone.0098685. eCollection 2014.

18.

Antigenic variation of clade 2.1 H5N1 virus is determined by a few amino acid substitutions immediately adjacent to the receptor binding site.

Koel BF, van der Vliet S, Burke DF, Bestebroer TM, Bharoto EE, Yasa IW, Herliana I, Laksono BM, Xu K, Skepner E, Russell CA, Rimmelzwaan GF, Perez DR, Osterhaus AD, Smith DJ, Prajitno TY, Fouchier RA.

MBio. 2014 Jun 10;5(3):e01070-14. doi: 10.1128/mBio.01070-14. Erratum in: MBio. 2014;5(4):doi:10.1128/mBio.01645-14.

19.

U4 at the 3' UTR of PB1 segment of H5N1 influenza virus promotes RNA polymerase activity and contributes to viral pathogenicity.

Sun W, Li J, Han P, Yang Y, Kang X, Li Y, Li J, Zhang Y, Wu X, Jiang T, Qin C, Hu Y, Zhu Q.

PLoS One. 2014 Mar 27;9(3):e93366. doi: 10.1371/journal.pone.0093366. eCollection 2014.

20.

Characterization of two distinct neuraminidases from avian-origin human-infecting H7N9 influenza viruses.

Wu Y, Bi Y, Vavricka CJ, Sun X, Zhang Y, Gao F, Zhao M, Xiao H, Qin C, He J, Liu W, Yan J, Qi J, Gao GF.

Cell Res. 2013 Dec;23(12):1347-55. doi: 10.1038/cr.2013.144. Epub 2013 Oct 29.

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