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Items: 1 to 20 of 88


Parkinson's disease-associated receptor GPR37 is an ER chaperone for LRP6.

Berger BS, Acebron SP, Herbst J, Koch S, Niehrs C.

EMBO Rep. 2017 May;18(5):712-725. doi: 10.15252/embr.201643585. Epub 2017 Mar 24.


Pathogenic LRRK2 variants are gain-of-function mutations that enhance LRRK2-mediated repression of β-catenin signaling.

Berwick DC, Javaheri B, Wetzel A, Hopkinson M, Nixon-Abell J, Grannò S, Pitsillides AA, Harvey K.

Mol Neurodegener. 2017 Jan 19;12(1):9. doi: 10.1186/s13024-017-0153-4.


Mice with a heterozygous Lrp6 deletion have impaired fracture healing.

Burgers TA, Vivanco JF, Zahatnansky J, Moren AJ, Mason JJ, Williams BO.

Bone Res. 2016 Sep 6;4:16025. doi: 10.1038/boneres.2016.25. eCollection 2016.


Integrated live imaging and molecular profiling of embryoid bodies reveals a synchronized progression of early differentiation.

Boxman J, Sagy N, Achanta S, Vadigepalli R, Nachman I.

Sci Rep. 2016 Aug 17;6:31623. doi: 10.1038/srep31623.


Mutations in WNT10B Are Identified in Individuals with Oligodontia.

Yu P, Yang W, Han D, Wang X, Guo S, Li J, Li F, Zhang X, Wong SW, Bai B, Liu Y, Du J, Sun ZS, Shi S, Feng H, Cai T.

Am J Hum Genet. 2016 Jul 7;99(1):195-201. doi: 10.1016/j.ajhg.2016.05.012. Epub 2016 Jun 16.


Wnt/β-catenin signaling plays an ever-expanding role in stem cell self-renewal, tumorigenesis and cancer chemoresistance.

Mohammed MK, Shao C, Wang J, Wei Q, Wang X, Collier Z, Tang S, Liu H, Zhang F, Huang J, Guo D, Lu M, Liu F, Liu J, Ma C, Shi LL, Athiviraham A, He TC, Lee MJ.

Genes Dis. 2016 Mar;3(1):11-40. Epub 2016 Jan 14.


Characterization of genetically engineered mouse models carrying Col2a1-cre-induced deletions of Lrp5 and/or Lrp6.

Schumacher CA, Joiner DM, Less KD, Drewry MO, Williams BO.

Bone Res. 2016 Mar 1;4:15042. doi: 10.1038/boneres.2015.42. eCollection 2016.


Pluripotency Factors on Their Lineage Move.

Weidgang CE, Seufferlein T, Kleger A, Mueller M.

Stem Cells Int. 2016;2016:6838253. doi: 10.1155/2016/6838253. Epub 2015 Dec 6. Review.


Novel Mode of Defective Neural Tube Closure in the Non-Obese Diabetic (NOD) Mouse Strain.

Salbaum JM, Kruger C, MacGowan J, Herion NJ, Burk D, Kappen C.

Sci Rep. 2015 Nov 23;5:16917. doi: 10.1038/srep16917.


Isoforms, structures, and functions of versatile spectraplakin MACF1.

Hu L, Su P, Li R, Yin C, Zhang Y, Shang P, Yang T, Qian A.

BMB Rep. 2016 Jan;49(1):37-44. doi: 10.5483/BMBRep.2016.49.1.185. Review.


Loss-of-Function Mutations in the WNT Co-receptor LRP6 Cause Autosomal-Dominant Oligodontia.

Massink MP, Créton MA, Spanevello F, Fennis WM, Cune MS, Savelberg SM, Nijman IJ, Maurice MM, van den Boogaard MJ, van Haaften G.

Am J Hum Genet. 2015 Oct 1;97(4):621-6. doi: 10.1016/j.ajhg.2015.08.014. Epub 2015 Sep 17.


Wnt/ß-catenin signalling and the dynamics of fate decisions in early mouse embryos and embryonic stem (ES) cells.

Muñoz-Descalzo S, Hadjantonakis AK, Arias AM.

Semin Cell Dev Biol. 2015 Dec;47-48:101-9. doi: 10.1016/j.semcdb.2015.08.011. Epub 2015 Aug 29. Review.


LRP6 in mesenchymal stem cells is required for bone formation during bone growth and bone remodeling.

Li C, Williams BO, Cao X, Wan M.

Bone Res. 2014 Apr 29;2:14006. doi: 10.1038/boneres.2014.6. eCollection 2014.


LDL Receptor-Related Protein 6 Modulates Ret Proto-Oncogene Signaling in Renal Development and Cystic Dysplasia.

Wang Y, Stokes A, Duan Z, Hui J, Xu Y, Chen Y, Chen HW, Lam K, Zhou CJ.

J Am Soc Nephrol. 2016 Feb;27(2):417-27. doi: 10.1681/ASN.2014100998. Epub 2015 Jun 5.


Canonical wnt signaling is required for commissural axon guidance.

Avilés EC, Stoeckli ET.

Dev Neurobiol. 2016 Feb;76(2):190-208. doi: 10.1002/dneu.22307. Epub 2015 Jul 3.


Quantitative phosphoproteome analysis of embryonic stem cell differentiation toward blood.

Piazzi M, Williamson A, Lee CF, Pearson S, Lacaud G, Kouskoff V, McCubrey JA, Cocco L, Whetton AD.

Oncotarget. 2015 May 10;6(13):10924-39.


Wnt-Lrp5 signaling regulates fatty acid metabolism in the osteoblast.

Frey JL, Li Z, Ellis JM, Zhang Q, Farber CR, Aja S, Wolfgang MJ, Clemens TL, Riddle RC.

Mol Cell Biol. 2015 Jun 1;35(11):1979-91. doi: 10.1128/MCB.01343-14. Epub 2015 Mar 23.


Updating the Wnt pathways.

Yu J, Virshup DM.

Biosci Rep. 2014 Oct 17;34(5). pii: e00142. doi: 10.1042/BSR20140119.


Unfolded protein response is required for the definitive endodermal specification of mouse embryonic stem cells via Smad2 and β-catenin signaling.

Xu H, Tsang KS, Wang Y, Chan JC, Xu G, Gao WQ.

J Biol Chem. 2014 Sep 19;289(38):26290-301. doi: 10.1074/jbc.M114.572560. Epub 2014 Aug 4.


Generation of organized germ layers from a single mouse embryonic stem cell.

Poh YC, Chen J, Hong Y, Yi H, Zhang S, Chen J, Wu DC, Wang L, Jia Q, Singh R, Yao W, Tan Y, Tajik A, Tanaka TS, Wang N.

Nat Commun. 2014 May 30;5:4000. doi: 10.1038/ncomms5000.

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