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Items: 1 to 20 of 33


Effects of resveratrol on drug- and carcinogen-metabolizing enzymes, implications for cancer prevention.

Guthrie AR, Chow HS, Martinez JA.

Pharmacol Res Perspect. 2017 Jan 31;5(1):e00294. doi: 10.1002/prp2.294. eCollection 2017 Feb. Review.


Ginsenoside Rb1 Inhibits Doxorubicin-Triggered H9C2 Cell Apoptosis via Aryl Hydrocarbon Receptor.

Zhang Y, Wang Y, Ma Z, Liang Q, Tang X, Tan H, Xiao C, Gao Y.

Biomol Ther (Seoul). 2017 Mar 1;25(2):202-212. doi: 10.4062/biomolther.2016.066.


Hop (Humulus lupulus L.) Extract and 6-Prenylnaringenin Induce P450 1A1 Catalyzed Estrogen 2-Hydroxylation.

Wang S, Dunlap TL, Howell CE, Mbachu OC, Rue EA, Phansalkar R, Chen SN, Pauli GF, Dietz BM, Bolton JL.

Chem Res Toxicol. 2016 Jul 18;29(7):1142-50. doi: 10.1021/acs.chemrestox.6b00112. Epub 2016 Jun 22.


The serotonin transporter promotes a pathological estrogen metabolic pathway in pulmonary hypertension via cytochrome P450 1B1.

Johansen AK, Dean A, Morecroft I, Hood K, Nilsen M, Loughlin L, Anagnostopoulou A, Touyz RM, White K, MacLean MR.

Pulm Circ. 2016 Mar;6(1):82-92. doi: 10.1086/685023.


Association between Blood Dioxin Level and Chronic Kidney Disease in an Endemic Area of Exposure.

Huang CY, Wu CL, Wu JS, Chang JW, Cheng YY, Kuo YC, Yang YC, Lee CC, Guo HR.

PLoS One. 2016 Mar 10;11(3):e0150248. doi: 10.1371/journal.pone.0150248. eCollection 2016.


Differential Effects of Glycyrrhiza Species on Genotoxic Estrogen Metabolism: Licochalcone A Downregulates P450 1B1, whereas Isoliquiritigenin Stimulates It.

Dunlap TL, Wang S, Simmler C, Chen SN, Pauli GF, Dietz BM, Bolton JL.

Chem Res Toxicol. 2015 Aug 17;28(8):1584-94. doi: 10.1021/acs.chemrestox.5b00157. Epub 2015 Jul 16.


Low levels of 3,3'-diindolylmethane activate estrogen receptor α and induce proliferation of breast cancer cells in the absence of estradiol.

Marques M, Laflamme L, Benassou I, Cissokho C, Guillemette B, Gaudreau L.

BMC Cancer. 2014 Jul 21;14:524. doi: 10.1186/1471-2407-14-524.


Resveratrol and endometrium: a closer look at an active ingredient of red wine using in vivo and in vitro models.

Amaya SC, Savaris RF, Filipovic CJ, Wise JD, Hestermann E, Young SL, Lessey BA.

Reprod Sci. 2014 Nov;21(11):1362-9. doi: 10.1177/1933719114525271. Epub 2014 Mar 6.


SERMs attenuate estrogen-induced malignant transformation of human mammary epithelial cells by upregulating detoxification of oxidative metabolites.

Hemachandra LP, Patel H, Chandrasena RE, Choi J, Piyankarage SC, Wang S, Wang Y, Thayer EN, Scism RA, Michalsen BT, Xiong R, Siklos MI, Bolton JL, Thatcher GR.

Cancer Prev Res (Phila). 2014 May;7(5):505-15. doi: 10.1158/1940-6207.CAPR-13-0296. Epub 2014 Mar 5.


Resveratrol potentiates effects of simvastatin on inhibition of rat ovarian theca-interstitial cells steroidogenesis.

Ortega I, Villanueva JA, Wong DH, Cress AB, Sokalska A, Stanley SD, Duleba AJ.

J Ovarian Res. 2014 Feb 13;7:21. doi: 10.1186/1757-2215-7-21.


Cytochrome P450 1B1 contributes to increased blood pressure and cardiovascular and renal dysfunction in spontaneously hypertensive rats.

Jennings BL, Montanez DE, May ME Jr, Estes AM, Fang XR, Yaghini FA, Kanu A, Malik KU.

Cardiovasc Drugs Ther. 2014 Apr;28(2):145-61. doi: 10.1007/s10557-014-6510-4.


Resveratrol protects against polychlorinated biphenyl-mediated impairment of glucose homeostasis in adipocytes.

Baker NA, English V, Sunkara M, Morris AJ, Pearson KJ, Cassis LA.

J Nutr Biochem. 2013 Dec;24(12):2168-74. doi: 10.1016/j.jnutbio.2013.08.009.


Should autism be considered a canary bird telling that Homo sapiens may be on its way to extinction?

Christophersen OA.

Microb Ecol Health Dis. 2012 Aug 24;23. doi: 10.3402/mehd.v23i0.19008. eCollection 2012.


The absence of ER-β results in altered gene expression in ovarian granulosa cells isolated from in vivo preovulatory follicles.

Binder AK, Rodriguez KF, Hamilton KJ, Stockton PS, Reed CE, Korach KS.

Endocrinology. 2013 Jun;154(6):2174-87. doi: 10.1210/en.2012-2256. Epub 2013 Apr 11.


A synergetic screening approach with companion effector for combination therapy: application to retinoblastoma.

Mahida JP, Antczak C, Decarlo D, Champ KG, Francis JH, Marr B, Polans AS, Albert DM, Abramson DH, Djaballah H.

PLoS One. 2013;8(3):e59156. doi: 10.1371/journal.pone.0059156. Epub 2013 Mar 19.


Raloxifene and desmethylarzoxifene block estrogen-induced malignant transformation of human breast epithelial cells.

Kastrati I, Edirisinghe PD, Hemachandra LP, Chandrasena ER, Choi J, Wang YT, Bolton JL, Thatcher GR.

PLoS One. 2011;6(11):e27876. doi: 10.1371/journal.pone.0027876. Epub 2011 Nov 29.


Hops (Humulus lupulus) inhibits oxidative estrogen metabolism and estrogen-induced malignant transformation in human mammary epithelial cells (MCF-10A).

Hemachandra LP, Madhubhani P, Chandrasena R, Esala P, Chen SN, Main M, Lankin DC, Scism RA, Dietz BM, Pauli GF, Thatcher GR, Bolton JL.

Cancer Prev Res (Phila). 2012 Jan;5(1):73-81. doi: 10.1158/1940-6207.CAPR-11-0348. Epub 2011 Oct 13.


Monocrotophos induced apoptosis in PC12 cells: role of xenobiotic metabolizing cytochrome P450s.

Kashyap MP, Singh AK, Kumar V, Tripathi VK, Srivastava RK, Agrawal M, Khanna VK, Yadav S, Jain SK, Pant AB.

PLoS One. 2011 Mar 21;6(3):e17757. doi: 10.1371/journal.pone.0017757.

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