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Protein Phosphatase 2A as a Therapeutic Target in Acute Myeloid Leukemia.

Arriazu E, Pippa R, Odero MD.

Front Oncol. 2016 Apr 6;6:78. doi: 10.3389/fonc.2016.00078. Review.


Silencing of IFN-stimulated gene transcription is regulated by histone H1 and its chaperone TAF-I.

Kadota S, Nagata K.

Nucleic Acids Res. 2014 Jul;42(12):7642-53. doi: 10.1093/nar/gku485.


Sorbitol dehydrogenase overexpression and other aspects of dysregulated protein expression in human precancerous colorectal neoplasms: a quantitative proteomics study.

Uzozie A, Nanni P, Staiano T, Grossmann J, Barkow-Oesterreicher S, Shay JW, Tiwari A, Buffoli F, Laczko E, Marra G.

Mol Cell Proteomics. 2014 May;13(5):1198-218. doi: 10.1074/mcp.M113.035105.


Transcriptional repressor NIR interacts with the p53-inhibiting ubiquitin ligase MDM2.

Heyne K, Förster J, Schüle R, Roemer K.

Nucleic Acids Res. 2014 Apr;42(6):3565-79. doi: 10.1093/nar/gkt1371.


Silencing PP2A inhibitor by lenti-shRNA interference ameliorates neuropathologies and memory deficits in tg2576 mice.

Liu GP, Wei W, Zhou X, Shi HR, Liu XH, Chai GS, Yao XQ, Zhang JY, Peng CX, Hu J, Li XC, Wang Q, Wang JZ.

Mol Ther. 2013 Dec;21(12):2247-57. doi: 10.1038/mt.2013.189.


LHX3 interacts with inhibitor of histone acetyltransferase complex subunits LANP and TAF-1β to modulate pituitary gene regulation.

Hunter CS, Malik RE, Witzmann FA, Rhodes SJ.

PLoS One. 2013 Jul 4;8(7):e68898. doi: 10.1371/journal.pone.0068898.


Targeted ANP32E mutant mice do not demonstrate obvious movement defects.

Wong P, Leo VI, Low M, Mak TW, Zhang X, Reilly PT.

PLoS One. 2013 May 13;8(5):e63815. doi: 10.1371/journal.pone.0063815.


The adenomatous polyposis coli protein contributes to normal compaction of mitotic chromatin.

Dikovskaya D, Khoudoli G, Newton IP, Chadha GS, Klotz D, Visvanathan A, Lamond A, Swedlow JR, Näthke IS.

PLoS One. 2012;7(6):e38102. doi: 10.1371/journal.pone.0038102.


Overexpression of SET is a recurrent event associated with poor outcome and contributes to protein phosphatase 2A inhibition in acute myeloid leukemia.

Cristóbal I, Garcia-Orti L, Cirauqui C, Cortes-Lavaud X, García-Sánchez MA, Calasanz MJ, Odero MD.

Haematologica. 2012 Apr;97(4):543-50. doi: 10.3324/haematol.2011.050542.


A peek into the complex realm of histone phosphorylation.

Banerjee T, Chakravarti D.

Mol Cell Biol. 2011 Dec;31(24):4858-73. doi: 10.1128/MCB.05631-11. Review.


Inhibition of p53 acetylation by INHAT subunit SET/TAF-Iβ represses p53 activity.

Kim JY, Lee KS, Seol JE, Yu K, Chakravarti D, Seo SB.

Nucleic Acids Res. 2012 Jan;40(1):75-87. doi: 10.1093/nar/gkr614.


Acidic nuclear phosphoprotein 32kDa (ANP32)B-deficient mouse reveals a hierarchy of ANP32 importance in mammalian development.

Reilly PT, Afzal S, Gorrini C, Lui K, Bukhman YV, Wakeham A, Haight J, Ling TW, Cheung CC, Elia AJ, Turner PV, Mak TW.

Proc Natl Acad Sci U S A. 2011 Jun 21;108(25):10243-8. doi: 10.1073/pnas.1106211108.


Differential expression of thrombospondin (THBS1) in tumorigenic and nontumorigenic prostate epithelial cells in response to a chromatin-binding soy peptide.

Galvez AF, Huang L, Magbanua MM, Dawson K, Rodriguez RL.

Nutr Cancer. 2011;63(4):623-36. doi: 10.1080/01635581.2011.539312.


The beta-arrestin pathway-selective type 1A angiotensin receptor (AT1A) agonist [Sar1,Ile4,Ile8]angiotensin II regulates a robust G protein-independent signaling network.

Kendall RT, Strungs EG, Rachidi SM, Lee MH, El-Shewy HM, Luttrell DK, Janech MG, Luttrell LM.

J Biol Chem. 2011 Jun 3;286(22):19880-91. doi: 10.1074/jbc.M111.233080.


Curing HIV: Pharmacologic approaches to target HIV-1 latency.

Choudhary SK, Margolis DM.

Annu Rev Pharmacol Toxicol. 2011;51:397-418. doi: 10.1146/annurev-pharmtox-010510-100237. Review.


pp32 (ANP32A) expression inhibits pancreatic cancer cell growth and induces gemcitabine resistance by disrupting HuR binding to mRNAs.

Williams TK, Costantino CL, Bildzukewicz NA, Richards NG, Rittenhouse DW, Einstein L, Cozzitorto JA, Keen JC, Dasgupta A, Gorospe M, Gonye GE, Yeo CJ, Witkiewicz AK, Brody JR.

PLoS One. 2010 Nov 29;5(11):e15455. doi: 10.1371/journal.pone.0015455.


Cellular and viral chromatin proteins are positive factors in the regulation of adenovirus gene expression.

Komatsu T, Haruki H, Nagata K.

Nucleic Acids Res. 2011 Feb;39(3):889-901. doi: 10.1093/nar/gkq783.


Proteomics analysis of the estrogen receptor alpha receptosome.

Nalvarte I, Schwend T, Gustafsson JA.

Mol Cell Proteomics. 2010 Jul;9(7):1411-22. doi: 10.1074/mcp.M900457-MCP200.


NIR, an inhibitor of histone acetyltransferases, regulates transcription factor TAp63 and is controlled by the cell cycle.

Heyne K, Willnecker V, Schneider J, Conrad M, Raulf N, Schüle R, Roemer K.

Nucleic Acids Res. 2010 Jun;38(10):3159-71. doi: 10.1093/nar/gkq016.

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