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Items: 1 to 20 of 24


Gq pathway regulates proximal C-type lectin-like receptor-2 (CLEC-2) signaling in platelets.

Badolia R, Inamdar V, Manne BK, Dangelmaier C, Eble JA, Kunapuli SP.

J Biol Chem. 2017 Sep 1;292(35):14516-14531. doi: 10.1074/jbc.M117.791012. Epub 2017 Jul 13.


Regulation, Signaling, and Physiological Functions of G-Proteins.

Syrovatkina V, Alegre KO, Dey R, Huang XY.

J Mol Biol. 2016 Sep 25;428(19):3850-68. doi: 10.1016/j.jmb.2016.08.002. Epub 2016 Aug 8. Review.


Calcific Aortic Valve Disease: Part 2-Morphomechanical Abnormalities, Gene Reexpression, and Gender Effects on Ventricular Hypertrophy and Its Reversibility.

Pasipoularides A.

J Cardiovasc Transl Res. 2016 Aug;9(4):374-99. doi: 10.1007/s12265-016-9695-z. Epub 2016 May 16. Review.


Metabotropic glutamate receptor-1 as a novel target for the antiangiogenic treatment of breast cancer.

Speyer CL, Hachem AH, Assi AA, Johnson JS, DeVries JA, Gorski DH.

PLoS One. 2014 Mar 14;9(3):e88830. doi: 10.1371/journal.pone.0088830. eCollection 2014.


Crosstalk between G protein-coupled receptors (GPCRs) and tyrosine kinase receptor (TXR) in the heart after morphine withdrawal.

Almela P, García-Carmona JA, Martínez-Laorden E, Milanés MV, Laorden ML.

Front Pharmacol. 2013 Dec 27;4:164. doi: 10.3389/fphar.2013.00164. eCollection 2013.


Metabotropic glutamate receptor-1 contributes to progression in triple negative breast cancer.

Banda M, Speyer CL, Semma SN, Osuala KO, Kounalakis N, Torres Torres KE, Barnard NJ, Kim HJ, Sloane BF, Miller FR, Goydos JS, Gorski DH.

PLoS One. 2014 Jan 3;9(1):e81126. doi: 10.1371/journal.pone.0081126. eCollection 2014.


Something old, something new and something borrowed: emerging paradigm of insulin-like growth factor type 1 receptor (IGF-1R) signaling regulation.

Girnita L, Worrall C, Takahashi S, Seregard S, Girnita A.

Cell Mol Life Sci. 2014 Jul;71(13):2403-27. doi: 10.1007/s00018-013-1514-y. Epub 2013 Nov 26. Review.


Orphan G protein receptor GPR55 as an emerging target in cancer therapy and management.

Leyva-Illades D, Demorrow S.

Cancer Manag Res. 2013 Jul 1;5:147-55. doi: 10.2147/CMAR.S35175. Print 2013.


RanBPM is an inhibitor of ERK signaling.

Atabakhsh E, Schild-Poulter C.

PLoS One. 2012;7(10):e47803. doi: 10.1371/journal.pone.0047803. Epub 2012 Oct 31.


Pertussis toxin, an inhibitor of G(αi) PCR, inhibits bile acid- and cytokine-induced apoptosis in primary rat hepatocytes.

Karimian G, Buist-Homan M, Faber KN, Moshage H.

PLoS One. 2012;7(8):e43156. doi: 10.1371/journal.pone.0043156. Epub 2012 Aug 10.


Resistance to inhibitors of cholinesterase-8A (Ric-8A) is critical for growth factor receptor-induced actin cytoskeletal reorganization.

Wang L, Guo D, Xing B, Zhang JJ, Shu HB, Guo L, Huang XY.

J Biol Chem. 2011 Sep 2;286(35):31055-61. doi: 10.1074/jbc.M111.253427. Epub 2011 Jul 19.


Metabotropic glutamate receptor-1: a potential therapeutic target for the treatment of breast cancer.

Speyer CL, Smith JS, Banda M, DeVries JA, Mekani T, Gorski DH.

Breast Cancer Res Treat. 2012 Apr;132(2):565-73. doi: 10.1007/s10549-011-1624-x. Epub 2011 Jun 17.


Chemokines: key players in cancer progression and metastasis.

Singh R, Lillard JW Jr, Singh S.

Front Biosci (Schol Ed). 2011 Jun 1;3:1569-82. Review.


Crosstalk between VEGFR2 and muscarinic receptors regulates the mTOR pathway in serum starved SK-N-SH human neuroblastoma cells.

Edelstein J, Hao T, Cao Q, Morales L, Rockwell P.

Cell Signal. 2011 Jan;23(1):239-48. doi: 10.1016/j.cellsig.2010.09.008. Epub 2010 Sep 16.


A G{alpha}i-GIV molecular complex binds epidermal growth factor receptor and determines whether cells migrate or proliferate.

Ghosh P, Beas AO, Bornheimer SJ, Garcia-Marcos M, Forry EP, Johannson C, Ear J, Jung BH, Cabrera B, Carethers JM, Farquhar MG.

Mol Biol Cell. 2010 Jul 1;21(13):2338-54. doi: 10.1091/mbc.E10-01-0028. Epub 2010 May 12.


Src-dependent TrkA transactivation is required for pituitary adenylate cyclase-activating polypeptide 38-mediated Rit activation and neuronal differentiation.

Shi GX, Jin L, Andres DA.

Mol Biol Cell. 2010 May 1;21(9):1597-608. doi: 10.1091/mbc.E09-12-1033. Epub 2010 Mar 10.


The ceramide-1-phosphate analogue PCERA-1 modulates tumour necrosis factor-alpha and interleukin-10 production in macrophages via the cAMP-PKA-CREB pathway in a GTP-dependent manner.

Avni D, Philosoph A, Meijler MM, Zor T.

Immunology. 2010 Mar;129(3):375-85. doi: 10.1111/j.1365-2567.2009.03188.x. Epub 2009 Nov 16.


17beta-estradiol-mediated neuroprotection and ERK activation require a pertussis toxin-sensitive mechanism involving GRK2 and beta-arrestin-1.

Dominguez R, Hu E, Zhou M, Baudry M.

J Neurosci. 2009 Apr 1;29(13):4228-38. doi: 10.1523/JNEUROSCI.0550-09.2009.


GIV is a nonreceptor GEF for G alpha i with a unique motif that regulates Akt signaling.

Garcia-Marcos M, Ghosh P, Farquhar MG.

Proc Natl Acad Sci U S A. 2009 Mar 3;106(9):3178-83. doi: 10.1073/pnas.0900294106. Epub 2009 Feb 11.


Activation of Galphai3 triggers cell migration via regulation of GIV.

Ghosh P, Garcia-Marcos M, Bornheimer SJ, Farquhar MG.

J Cell Biol. 2008 Jul 28;182(2):381-93. doi: 10.1083/jcb.200712066.

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