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Items: 1 to 20 of 124


A novel p.T139M mutation in HSPB1 highlighting the phenotypic spectrum in a family.

Amornvit J, Yalvac ME, Chen L, Sahenk Z.

Brain Behav. 2017 Jul 21;7(8):e00774. doi: 10.1002/brb3.774. eCollection 2017 Aug.


HSPB1 mutations causing hereditary neuropathy in humans disrupt non-cell autonomous protection of motor neurons.

Heilman PL, Song S, Miranda CJ, Meyer K, Srivastava AK, Knapp A, Wier CG, Kaspar BK, Kolb SJ.

Exp Neurol. 2017 Nov;297:101-109. doi: 10.1016/j.expneurol.2017.08.002. Epub 2017 Aug 7.


Mechanical signals activate p38 MAPK pathway-dependent reinforcement of actin via mechanosensitive HspB1.

Hoffman L, Jensen CC, Yoshigi M, Beckerle M.

Mol Biol Cell. 2017 Oct 1;28(20):2661-2675. doi: 10.1091/mbc.E17-02-0087. Epub 2017 Aug 2.


Acetylation-induced TDP-43 pathology is suppressed by an HSF1-dependent chaperone program.

Wang P, Wander CM, Yuan CX, Bereman MS, Cohen TJ.

Nat Commun. 2017 Jul 19;8(1):82. doi: 10.1038/s41467-017-00088-4.


The ALS-linked E102Q mutation in Sigma receptor-1 leads to ER stress-mediated defects in protein homeostasis and dysregulation of RNA-binding proteins.

Dreser A, Vollrath JT, Sechi A, Johann S, Roos A, Yamoah A, Katona I, Bohlega S, Wiemuth D, Tian Y, Schmidt A, Vervoorts J, Dohmen M, Beyer C, Anink J, Aronica E, Troost D, Weis J, Goswami A.

Cell Death Differ. 2017 Oct;24(10):1655-1671. doi: 10.1038/cdd.2017.88. Epub 2017 Jun 16.


Proline isomerization in the C-terminal region of HSP27.

Alderson TR, Benesch JLP, Baldwin AJ.

Cell Stress Chaperones. 2017 Jul;22(4):639-651. doi: 10.1007/s12192-017-0791-z. Epub 2017 May 25.


Granulostasis: Protein Quality Control of RNP Granules.

Alberti S, Mateju D, Mediani L, Carra S.

Front Mol Neurosci. 2017 Mar 27;10:84. doi: 10.3389/fnmol.2017.00084. eCollection 2017. Review.


The growing world of small heat shock proteins: from structure to functions.

Carra S, Alberti S, Arrigo PA, Benesch JL, Benjamin IJ, Boelens W, Bartelt-Kirbach B, Brundel BJJM, Buchner J, Bukau B, Carver JA, Ecroyd H, Emanuelsson C, Finet S, Golenhofen N, Goloubinoff P, Gusev N, Haslbeck M, Hightower LE, Kampinga HH, Klevit RE, Liberek K, Mchaourab HS, McMenimen KA, Poletti A, Quinlan R, Strelkov SV, Toth ME, Vierling E, Tanguay RM.

Cell Stress Chaperones. 2017 Jul;22(4):601-611. doi: 10.1007/s12192-017-0787-8. Epub 2017 Mar 31. Review.


An interaction study in mammalian cells demonstrates weak binding of HSPB2 to BAG3, which is regulated by HSPB3 and abrogated by HSPB8.

Morelli FF, Mediani L, Heldens L, Bertacchini J, Bigi I, Carrà AD, Vinet J, Carra S.

Cell Stress Chaperones. 2017 Jul;22(4):531-540. doi: 10.1007/s12192-017-0769-x. Epub 2017 Feb 8.


Chaperone activity of human small heat shock protein-GST fusion proteins.

Arbach H, Butler C, McMenimen KA.

Cell Stress Chaperones. 2017 Jul;22(4):503-515. doi: 10.1007/s12192-017-0764-2. Epub 2017 Jan 27.


HDAC6 Inhibitors Rescued the Defective Axonal Mitochondrial Movement in Motor Neurons Derived from the Induced Pluripotent Stem Cells of Peripheral Neuropathy Patients with HSPB1 Mutation.

Kim JY, Woo SY, Hong YB, Choi H, Kim J, Choi H, Mook-Jung I, Ha N, Kyung J, Koo SK, Jung SC, Choi BO.

Stem Cells Int. 2016;2016:9475981. doi: 10.1155/2016/9475981. Epub 2016 Dec 26.


Mutant HSPB1 causes loss of translational repression by binding to PCBP1, an RNA binding protein with a possible role in neurodegenerative disease.

Geuens T, De Winter V, Rajan N, Achsel T, Mateiu L, Almeida-Souza L, Asselbergh B, Bouhy D, Auer-Grumbach M, Bagni C, Timmerman V.

Acta Neuropathol Commun. 2017 Jan 11;5(1):5. doi: 10.1186/s40478-016-0407-3.


Small heat shock proteins in ageing and age-related diseases.

Charmpilas N, Kyriakakis E, Tavernarakis N.

Cell Stress Chaperones. 2017 Jul;22(4):481-492. doi: 10.1007/s12192-016-0761-x. Epub 2017 Jan 10. Review.


Chaperonopathies: Spotlight on Hereditary Motor Neuropathies.

Lupo V, Aguado C, Knecht E, Espinós C.

Front Mol Biosci. 2016 Dec 14;3:81. doi: 10.3389/fmolb.2016.00081. eCollection 2016. Review.


Interaction of small heat shock proteins with light component of neurofilaments (NFL).

Nefedova VV, Sudnitsyna MV, Gusev NB.

Cell Stress Chaperones. 2017 Jul;22(4):467-479. doi: 10.1007/s12192-016-0757-6. Epub 2016 Dec 20.


Development of Improved HDAC6 Inhibitors as Pharmacological Therapy for Axonal Charcot-Marie-Tooth Disease.

Benoy V, Vanden Berghe P, Jarpe M, Van Damme P, Robberecht W, Van Den Bosch L.

Neurotherapeutics. 2017 Apr;14(2):417-428. doi: 10.1007/s13311-016-0501-z.


Oligomerization and chaperone-like activity of Drosophila melanogaster small heat shock protein DmHsp27 and three arginine mutants in the alpha-crystallin domain.

Moutaoufik MT, Morrow G, Maaroufi H, Férard C, Finet S, Tanguay RM.

Cell Stress Chaperones. 2017 Jul;22(4):455-466. doi: 10.1007/s12192-016-0748-7. Epub 2016 Dec 8.


Pilot phenotype and natural history study of hereditary neuropathies caused by mutations in the HSPB1 gene.

Rossor AM, Morrow JM, Polke JM, Murphy SM, Houlden H; INC-RDCRC, Laura M, Manji H, Blake J, Reilly MM.

Neuromuscul Disord. 2017 Jan;27(1):50-56. doi: 10.1016/j.nmd.2016.10.001. Epub 2016 Oct 8.


Changes to the Aqueous Humor Proteome during Glaucoma.

Kaeslin MA, Killer HE, Fuhrer CA, Zeleny N, Huber AR, Neutzner A.

PLoS One. 2016 Oct 27;11(10):e0165314. doi: 10.1371/journal.pone.0165314. eCollection 2016.


Heat shock protein 27 is a potential indicator for response to YangZheng XiaoJi and chemotherapy agents in cancer cells.

Owen S, Zhao H, Dart A, Wang Y, Ruge F, Gao Y, Wei C, Wu Y, Jiang WG.

Int J Oncol. 2016 Nov;49(5):1839-1847. doi: 10.3892/ijo.2016.3685. Epub 2016 Sep 6.

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