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Neutrophil Extracellular Traps in Pulmonary Diseases: Too Much of a Good Thing?

Porto BN, Stein RT.

Front Immunol. 2016 Aug 15;7:311. doi: 10.3389/fimmu.2016.00311. Review.


Effect of Fluoroquinolones and Macrolides on Eradication and Resistance of Haemophilus influenzae in Chronic Obstructive Pulmonary Disease.

Pettigrew MM, Tsuji BT, Gent JF, Kong Y, Holden PN, Sethi S, Murphy TF.

Antimicrob Agents Chemother. 2016 Jun 20;60(7):4151-8. doi: 10.1128/AAC.00301-16.


Transformed Recombinant Enrichment Profiling Rapidly Identifies HMW1 as an Intracellular Invasion Locus in Haemophilus influenza.

Mell JC, Viadas C, Moleres J, Sinha S, Fernández-Calvet A, Porsch EA, St Geme JW 3rd, Nislow C, Redfield RJ, Garmendia J.

PLoS Pathog. 2016 Apr 28;12(4):e1005576. doi: 10.1371/journal.ppat.1005576. Erratum in: PLoS Pathog. 2016 May;12(5):e1005681.


Haemophilus influenzae induces steroid-resistant inflammatory responses in COPD.

Cosío BG, Jahn A, Iglesias A, Shafiek H, Busquets X, Agustí A.

BMC Pulm Med. 2015 Dec 7;15:157. doi: 10.1186/s12890-015-0155-3.


Small airway epithelial-C/EBPβ is increased in patients with advanced COPD.

Mori M, Bjermer L, Erjefält JS, Stampfli MR, Roos AB.

Respir Res. 2015 Oct 29;16:133. doi: 10.1186/s12931-015-0297-0.


Bacterial exploitation of phosphorylcholine mimicry suppresses inflammation to promote airway infection.

Hergott CB, Roche AM, Naidu NA, Mesaros C, Blair IA, Weiser JN.

J Clin Invest. 2015 Oct 1;125(10):3878-90. doi: 10.1172/JCI81888.


Genome Expression Profiling-Based Identification and Administration Efficacy of Host-Directed Antimicrobial Drugs against Respiratory Infection by Nontypeable Haemophilus influenzae.

Euba B, Moleres J, Segura V, Viadas C, Morey P, Moranta D, Leiva J, de-Torres JP, Bengoechea JA, Garmendia J.

Antimicrob Agents Chemother. 2015 Dec;59(12):7581-92. doi: 10.1128/AAC.01278-15.


Determinants of bacteriological outcomes in exacerbations of chronic obstructive pulmonary disease.

Sethi S, Anzueto A, Miravitlles M, Arvis P, Alder J, Haverstock D, Trajanovic M, Wilson R.

Infection. 2016 Feb;44(1):65-76. doi: 10.1007/s15010-015-0833-3.


Rationale and Design of the Genomic Research in Alpha-1 Antitrypsin Deficiency and Sarcoidosis Study. Alpha-1 Protocol.

Strange C, Senior RM, Sciurba F, O'Neal S, Morris A, Wisniewski SR, Bowler R, Hochheiser HS, Becich MJ, Zhang Y, Leader JK, Methé BA, Kaminski N, Sandhaus RA; GRADS Alpha-1 Study Group..

Ann Am Thorac Soc. 2015 Oct;12(10):1551-60. doi: 10.1513/AnnalsATS.201503-143OC.


The Lung Immune Response to Nontypeable Haemophilus influenzae (Lung Immunity to NTHi).

King PT, Sharma R.

J Immunol Res. 2015;2015:706376. doi: 10.1155/2015/706376. Review.


Airway bacteria measured by quantitative polymerase chain reaction and culture in patients with stable COPD: relationship with neutrophilic airway inflammation, exacerbation frequency, and lung function.

Bafadhel M, Haldar K, Barker B, Patel H, Mistry V, Barer MR, Pavord ID, Brightling CE.

Int J Chron Obstruct Pulmon Dis. 2015 Jun 9;10:1075-83. doi: 10.2147/COPD.S80091.


The existence of bronchiectasis predicts worse prognosis in patients with COPD.

Mao B, Lu HW, Li MH, Fan LC, Yang JW, Miao XY, Xu JF.

Sci Rep. 2015 Jun 16;5:10961. doi: 10.1038/srep10961.


Expression of IgA Proteases by Haemophilus influenzae in the Respiratory Tract of Adults With Chronic Obstructive Pulmonary Disease.

Murphy TF, Kirkham C, Jones MM, Sethi S, Kong Y, Pettigrew MM.

J Infect Dis. 2015 Dec 1;212(11):1798-805. doi: 10.1093/infdis/jiv299.


Respiratory infection by Corynebacterium striatum: epidemiological and clinical determinants.

Renom F, Gomila M, Garau M, Gallegos MD, Guerrero D, Lalucat J, Soriano JB.

New Microbes New Infect. 2014 Jul;2(4):106-14. doi: 10.1002/nmi2.48.


Peroxiredoxin-glutaredoxin and catalase promote resistance of nontypeable Haemophilus influenzae 86-028NP to oxidants and survival within neutrophil extracellular traps.

Juneau RA, Pang B, Armbruster CE, Murrah KA, Perez AC, Swords WE.

Infect Immun. 2015 Jan;83(1):239-46. doi: 10.1128/IAI.02390-14.


Lower airway colonization and inflammatory response in COPD: a focus on Haemophilus influenzae.

Finney LJ, Ritchie A, Pollard E, Johnston SL, Mallia P.

Int J Chron Obstruct Pulmon Dis. 2014 Oct 13;9:1119-32. doi: 10.2147/COPD.S54477. Review.


Inflammatory thresholds and the species-specific effects of colonising bacteria in stable chronic obstructive pulmonary disease.

Singh R, Mackay AJ, Patel AR, Garcha DS, Kowlessar BS, Brill SE, Donnelly LE, Barnes PJ, Donaldson GC, Wedzicha JA.

Respir Res. 2014 Sep 14;15:114. doi: 10.1186/s12931-014-0114-1.


Airway epithelial platelet-activating factor receptor expression is markedly upregulated in chronic obstructive pulmonary disease.

Shukla SD, Sohal SS, Mahmood MQ, Reid D, Muller HK, Walters EH.

Int J Chron Obstruct Pulmon Dis. 2014 Aug 13;9:853-61. doi: 10.2147/COPD.S67044.

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