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Lack of concordance between residual viremia and viral variants driving de novo infection of CD4(+) T cells on ART.

Puertas MC, Noguera-Julian M, Massanella M, Pou C, Buzon MJ, Clotet B, Stevenson M, Paredes R, Blanco J, Martinez-Picado J.

Retrovirology. 2016 Aug 2;13(1):51. doi: 10.1186/s12977-016-0282-9.


Immunological and pharmacological strategies to reactivate HIV-1 from latently infected cells: a possibility for HIV-1 paediatric patients?

Martínez-Bonet M, Clemente MI, Serramía MJ, Moreno S, Muñoz E, Muñoz-Fernández MA.

J Virus Erad. 2015 Jul 1;1(3):148-52. Review.


Host Double Strand Break Repair Generates HIV-1 Strains Resistant to CRISPR/Cas9.

Yoder KE, Bundschuh R.

Sci Rep. 2016 Jul 12;6:29530. doi: 10.1038/srep29530.


The Latent Reservoir for HIV-1: How Immunologic Memory and Clonal Expansion Contribute to HIV-1 Persistence.

Murray AJ, Kwon KJ, Farber DL, Siliciano RF.

J Immunol. 2016 Jul 15;197(2):407-17. doi: 10.4049/jimmunol.1600343. Review.


Real-Time Predictions of Reservoir Size and Rebound Time during Antiretroviral Therapy Interruption Trials for HIV.

Hill AL, Rosenbloom DI, Goldstein E, Hanhauser E, Kuritzkes DR, Siliciano RF, Henrich TJ.

PLoS Pathog. 2016 Apr 27;12(4):e1005535. doi: 10.1371/journal.ppat.1005535. Erratum in: PLoS Pathog. 2016 Jul;12(7):e1005778.


Measuring the latent reservoir in vivo.

Massanella M, Richman DD.

J Clin Invest. 2016 Feb;126(2):464-72. doi: 10.1172/JCI80567. Review.


Residual Viremia in Treated HIV+ Individuals.

Conway JM, Perelson AS.

PLoS Comput Biol. 2016 Jan 6;12(1):e1004677. doi: 10.1371/journal.pcbi.1004677.


Well-mixed plasma and tissue viral populations in RT-SHIV-infected macaques implies a lack of viral replication in the tissues during antiretroviral therapy.

Kearney MF, Anderson EM, Coomer C, Smith L, Shao W, Johnson N, Kline C, Spindler J, Mellors JW, Coffin JM, Ambrose Z.

Retrovirology. 2015 Nov 11;12:93. doi: 10.1186/s12977-015-0212-2.


Activation and lysis of human CD4 cells latently infected with HIV-1.

Pegu A, Asokan M, Wu L, Wang K, Hataye J, Casazza JP, Guo X, Shi W, Georgiev I, Zhou T, Chen X, O'Dell S, Todd JP, Kwong PD, Rao SS, Yang ZY, Koup RA, Mascola JR, Nabel GJ.

Nat Commun. 2015 Oct 20;6:8447. doi: 10.1038/ncomms9447.


Transcriptional Changes in CD8(+) T Cells During Antiretroviral Therapy Intensified With Raltegravir.

Ouyang Z, Buzon MJ, Zheng L, Sun H, Yu XG, Bosch RJ, Mellors JW, Eron JJ, Gandhi RT, Lichterfeld M.

Open Forum Infect Dis. 2015 Apr 1;2(2):ofv045. doi: 10.1093/ofid/ofv045.


Towards an HIV-1 cure: measuring the latent reservoir.

Bruner KM, Hosmane NN, Siliciano RF.

Trends Microbiol. 2015 Apr;23(4):192-203. doi: 10.1016/j.tim.2015.01.013. Review.


Epigenetic heterogeneity in HIV-1 latency establishment.

Matsuda Y, Kobayashi-Ishihara M, Fujikawa D, Ishida T, Watanabe T, Yamagishi M.

Sci Rep. 2015 Jan 9;5:7701. doi: 10.1038/srep07701.


Potential implication of residual viremia in patients on effective antiretroviral therapy.

Sahu GK.

AIDS Res Hum Retroviruses. 2015 Jan;31(1):25-35. doi: 10.1089/AID.2014.0194. Review.


Eradicating HIV-1 infection: seeking to clear a persistent pathogen.

Archin NM, Sung JM, Garrido C, Soriano-Sarabia N, Margolis DM.

Nat Rev Microbiol. 2014 Nov;12(11):750-64. doi: 10.1038/nrmicro3352. Review.


Reduced evolutionary rates in HIV-1 reveal extensive latency periods among replicating lineages.

Immonen TT, Leitner T.

Retrovirology. 2014 Oct 16;11:81. doi: 10.1186/s12977-014-0081-0.


Predicting the outcomes of treatment to eradicate the latent reservoir for HIV-1.

Hill AL, Rosenbloom DI, Fu F, Nowak MA, Siliciano RF.

Proc Natl Acad Sci U S A. 2014 Sep 16;111(37):13475-80. doi: 10.1073/pnas.1406663111. Erratum in: Proc Natl Acad Sci U S A. 2014 Oct 28;111(43):15598.


Association between latent proviral characteristics and immune activation in antiretrovirus-treated human immunodeficiency virus type 1-infected adults.

Liang EC, Sceats L, Bayless NL, Strauss-Albee DM, Kubo J, Grant PM, Furman D, Desai M, Katzenstein DA, Davis MM, Zolopa AR, Blish CA.

J Virol. 2014 Aug;88(15):8629-39. doi: 10.1128/JVI.01257-14.


The genealogical population dynamics of HIV-1 in a large transmission chain: bridging within and among host evolutionary rates.

Vrancken B, Rambaut A, Suchard MA, Drummond A, Baele G, Derdelinckx I, Van Wijngaerden E, Vandamme AM, Van Laethem K, Lemey P.

PLoS Comput Biol. 2014 Apr 3;10(4):e1003505. doi: 10.1371/journal.pcbi.1003505.


Residual viremia in an RT-SHIV rhesus macaque HAART model marked by the presence of a predominant plasma clone and a lack of viral evolution.

Kauffman RC, Villalobos A, Bowen JH, Adamson L, Schinazi RF.

PLoS One. 2014 Feb 5;9(2):e88258. doi: 10.1371/journal.pone.0088258.


Persistence of viral reservoirs in multiple tissues after antiretroviral therapy suppression in a macaque RT-SHIV model.

Kline C, Ndjomou J, Franks T, Kiser R, Coalter V, Smedley J, Piatak M Jr, Mellors JW, Lifson JD, Ambrose Z.

PLoS One. 2013 Dec 18;8(12):e84275. doi: 10.1371/journal.pone.0084275.

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