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Items: 1 to 20 of 43

1.

VHL promotes immune response against renal cell carcinoma via NF-κB-dependent regulation of VCAM-1.

Labrousse-Arias D, Martínez-Alonso E, Corral-Escariz M, Bienes-Martínez R, Berridy J, Serrano-Oviedo L, Conde E, García-Bermejo ML, Giménez-Bachs JM, Salinas-Sánchez AS, Sánchez-Prieto R, Yao M, Lasa M, Calzada MJ.

J Cell Biol. 2017 Mar 6;216(3):835-847. doi: 10.1083/jcb.201608024. Epub 2017 Feb 24.

2.

Molecular markers of paragangliomas/pheochromocytomas.

Zhikrivetskaya SO, Snezhkina AV, Zaretsky AR, Alekseev BY, Pokrovsky AV, Golovyuk AL, Melnikova NV, Stepanov OA, Kalinin DV, Moskalev AA, Krasnov GS, Dmitriev AA, Kudryavtseva AV.

Oncotarget. 2017 Apr 11;8(15):25756-25782. doi: 10.18632/oncotarget.15201. Review.

3.

A Late G1 Lipid Checkpoint That Is Dysregulated in Clear Cell Renal Carcinoma Cells.

Patel D, Salloum D, Saqcena M, Chatterjee A, Mroz V, Ohh M, Foster DA.

J Biol Chem. 2017 Jan 20;292(3):936-944. doi: 10.1074/jbc.M116.757864. Epub 2016 Dec 12.

PMID:
27956548
4.

Ubiquitin-Mediated Regulation of Cell Death, Inflammation, and Defense of Homeostasis.

Meier P, Morris O, Broemer M.

Curr Top Dev Biol. 2015;114:209-39. doi: 10.1016/bs.ctdb.2015.07.015. Epub 2015 Sep 11. Review.

5.

Insights into Cullin-RING E3 ubiquitin ligase recruitment: structure of the VHL-EloBC-Cul2 complex.

Nguyen HC, Yang H, Fribourgh JL, Wolfe LS, Xiong Y.

Structure. 2015 Mar 3;23(3):441-9. doi: 10.1016/j.str.2014.12.014. Epub 2015 Feb 5.

6.

Stabilization of LKB1 and Akt by neddylation regulates energy metabolism in liver cancer.

Barbier-Torres L, Delgado TC, García-Rodríguez JL, Zubiete-Franco I, Fernández-Ramos D, Buqué X, Cano A, Gutiérrez-de Juan V, Fernández-Domínguez I, Lopitz-Otsoa F, Fernández-Tussy P, Boix L, Bruix J, Villa E, Castro A, Lu SC, Aspichueta P, Xirodimas D, Varela-Rey M, Mato JM, Beraza N, Martínez-Chantar ML.

Oncotarget. 2015 Feb 10;6(4):2509-23.

7.

Neddylation and deneddylation in cardiac biology.

Kandala S, Kim IM, Su H.

Am J Cardiovasc Dis. 2014 Dec 29;4(4):140-58. eCollection 2014. Review.

8.

Protein neddylation: beyond cullin-RING ligases.

Enchev RI, Schulman BA, Peter M.

Nat Rev Mol Cell Biol. 2015 Jan;16(1):30-44. doi: 10.1038/nrm3919. Review.

9.

Identification of NAE Inhibitors Exhibiting Potent Activity in Leukemia Cells: Exploring the Structural Determinants of NAE Specificity.

Lukkarila JL, da Silva SR, Ali M, Shahani VM, Xu GW, Berman J, Roughton A, Dhe-Paganon S, Schimmer AD, Gunning PT.

ACS Med Chem Lett. 2011 May 16;2(8):577-82. doi: 10.1021/ml2000615. eCollection 2011 Aug 11.

10.

The NEDD8 modification pathway in plants.

Mergner J, Schwechheimer C.

Front Plant Sci. 2014 Mar 21;5:103. doi: 10.3389/fpls.2014.00103. eCollection 2014. Review.

11.

Targeting Neddylation pathways to inactivate cullin-RING ligases for anticancer therapy.

Zhao Y, Morgan MA, Sun Y.

Antioxid Redox Signal. 2014 Dec 10;21(17):2383-400. doi: 10.1089/ars.2013.5795. Epub 2014 Feb 20. Review.

12.

Targeting both IGF-1R and mTOR synergistically inhibits growth of renal cell carcinoma in vitro.

Cardillo TM, Trisal P, Arrojo R, Goldenberg DM, Chang CH.

BMC Cancer. 2013 Apr 1;13:170. doi: 10.1186/1471-2407-13-170.

13.

DCNL1 functions as a substrate sensor and activator of cullin 2-RING ligase.

Heir P, Sufan RI, Greer SN, Poon BP, Lee JE, Ohh M.

Mol Cell Biol. 2013 Apr;33(8):1621-31. doi: 10.1128/MCB.01342-12. Epub 2013 Feb 11.

14.

Modification by ubiquitin-like proteins: significance in apoptosis and autophagy pathways.

Cajee UF, Hull R, Ntwasa M.

Int J Mol Sci. 2012;13(9):11804-31. doi: 10.3390/ijms130911804. Epub 2012 Sep 19. Review.

15.

Regulation of hypoxia-inducible factor 2-a is essential for integrity of the glomerular barrier.

Ding M, Coward RJ, Jeansson M, Kim W, Quaggin SE.

Am J Physiol Renal Physiol. 2013 Jan 1;304(1):F120-6. doi: 10.1152/ajprenal.00416.2012. Epub 2012 Oct 10.

16.

State of the science: an update on renal cell carcinoma.

Jonasch E, Futreal PA, Davis IJ, Bailey ST, Kim WY, Brugarolas J, Giaccia AJ, Kurban G, Pause A, Frydman J, Zurita AJ, Rini BI, Sharma P, Atkins MB, Walker CL, Rathmell WK.

Mol Cancer Res. 2012 Jul;10(7):859-80. doi: 10.1158/1541-7786.MCR-12-0117. Epub 2012 May 25. Review.

17.

The p53 inhibitor pifithrin-α can stimulate fibrosis in a rat model of ischemic acute kidney injury.

Dagher PC, Mai EM, Hato T, Lee SY, Anderson MD, Karozos SC, Mang HE, Knipe NL, Plotkin Z, Sutton TA.

Am J Physiol Renal Physiol. 2012 Jan 15;302(2):F284-91. doi: 10.1152/ajprenal.00317.2011. Epub 2011 Nov 2.

18.

Changes in the ratio of free NEDD8 to ubiquitin triggers NEDDylation by ubiquitin enzymes.

Hjerpe R, Thomas Y, Chen J, Zemla A, Curran S, Shpiro N, Dick LR, Kurz T.

Biochem J. 2012 Feb 1;441(3):927-36. doi: 10.1042/BJ20111671.

19.

The NEDD8 Conjugation Pathway and Its Relevance in Cancer Biology and Therapy.

Soucy TA, Dick LR, Smith PG, Milhollen MA, Brownell JE.

Genes Cancer. 2010 Jul;1(7):708-16. doi: 10.1177/1947601910382898.

20.

New insights into the biology of renal cell carcinoma.

Li L, Kaelin WG Jr.

Hematol Oncol Clin North Am. 2011 Aug;25(4):667-86. doi: 10.1016/j.hoc.2011.04.004. Review.

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