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Items: 1 to 20 of 26


Genome-wide screening for genetic alterations in esophageal cancer by aCGH identifies 11q13 amplification oncogenes associated with nodal metastasis.

Ying J, Shan L, Li J, Zhong L, Xue L, Zhao H, Li L, Langford C, Guo L, Qiu T, Lu N, Tao Q.

PLoS One. 2012;7(6):e39797. doi: 10.1371/journal.pone.0039797. Epub 2012 Jun 25.


Divergent genomic and epigenomic landscapes of lung cancer subtypes underscore the selection of different oncogenic pathways during tumor development.

Lockwood WW, Wilson IM, Coe BP, Chari R, Pikor LA, Thu KL, Solis LM, Nunez MI, Behrens C, Yee J, English J, Murray N, Tsao MS, Minna JD, Gazdar AF, Wistuba II, MacAulay CE, Lam S, Lam WL.

PLoS One. 2012;7(5):e37775. doi: 10.1371/journal.pone.0037775. Epub 2012 May 21.


Integrative genomic analyses identify BRF2 as a novel lineage-specific oncogene in lung squamous cell carcinoma.

Lockwood WW, Chari R, Coe BP, Thu KL, Garnis C, Malloff CA, Campbell J, Williams AC, Hwang D, Zhu CQ, Buys TP, Yee J, English JC, Macaulay C, Tsao MS, Gazdar AF, Minna JD, Lam S, Lam WL.

PLoS Med. 2010 Jul 27;7(7):e1000315. doi: 10.1371/journal.pmed.1000315.


Integrating the multiple dimensions of genomic and epigenomic landscapes of cancer.

Chari R, Thu KL, Wilson IM, Lockwood WW, Lonergan KM, Coe BP, Malloff CA, Gazdar AF, Lam S, Garnis C, MacAulay CE, Alvarez CE, Lam WL.

Cancer Metastasis Rev. 2010 Mar;29(1):73-93. doi: 10.1007/s10555-010-9199-2. Review.


Constitutively overexpressed 21 kDa protein in Hodgkin lymphoma and aggressive non-Hodgkin lymphomas identified as cytochrome B5b (CYB5B).

Murphy D, Parker J, Zhou M, Fadlelmola FM, Steidl C, Karsan A, Gascoyne RD, Chen H, Banerjee D.

Mol Cancer. 2010 Jan 26;9:14. doi: 10.1186/1476-4598-9-14.


Genomic imbalances in precancerous tissues signal oral cancer risk.

Garnis C, Chari R, Buys TP, Zhang L, Ng RT, Rosin MP, Lam WL.

Mol Cancer. 2009 Jul 23;8:50. doi: 10.1186/1476-4598-8-50.


Multiple aberrations of chromosome 3p detected in oral premalignant lesions.

Tsui IF, Rosin MP, Zhang L, Ng RT, Lam WL.

Cancer Prev Res (Phila). 2008 Nov;1(6):424-9. doi: 10.1158/1940-6207.CAPR-08-0123.


Technical demonstration of whole genome array comparative genomic hybridization.

Kennett JY, Watson SK, Saprunoff H, Heryet C, Lam WL.

J Vis Exp. 2008 Aug 5;(18). pii: 870. doi: 10.3791/870.


Genomic markers for malignant progression in pulmonary adenocarcinoma with bronchioloalveolar features.

Aviel-Ronen S, Coe BP, Lau SK, da Cunha Santos G, Zhu CQ, Strumpf D, Jurisica I, Lam WL, Tsao MS.

Proc Natl Acad Sci U S A. 2008 Jul 22;105(29):10155-60. doi: 10.1073/pnas.0709618105. Epub 2008 Jul 15.


MD-SeeGH: a platform for integrative analysis of multi-dimensional genomic data.

Chi B, deLeeuw RJ, Coe BP, Ng RT, MacAulay C, Lam WL.

BMC Bioinformatics. 2008 May 20;9:243. doi: 10.1186/1471-2105-9-243.


DNA amplification is a ubiquitous mechanism of oncogene activation in lung and other cancers.

Lockwood WW, Chari R, Coe BP, Girard L, Macaulay C, Lam S, Gazdar AF, Minna JD, Lam WL.

Oncogene. 2008 Jul 31;27(33):4615-24. doi: 10.1038/onc.2008.98. Epub 2008 Apr 7.


Computational methods for the analysis of array comparative genomic hybridization.

Chari R, Lockwood WW, Lam WL.

Cancer Inform. 2007 Feb 10;2:48-58.


Epidermal growth factor receptor (EGFR) is transcriptionally induced by the Y-box binding protein-1 (YB-1) and can be inhibited with Iressa in basal-like breast cancer, providing a potential target for therapy.

Stratford AL, Habibi G, Astanehe A, Jiang H, Hu K, Park E, Shadeo A, Buys TP, Lam W, Pugh T, Marra M, Nielsen TO, Klinge U, Mertens PR, Aparicio S, Dunn SE.

Breast Cancer Res. 2007;9(5):R61.


aCGHViewer: a generic visualization tool for aCGH data.

Shankar G, Rossi MR, McQuaid DE, Conroy JM, Gaile DG, Cowell JK, Nowak NJ, Liang P.

Cancer Inform. 2006;2:36-43.


A comprehensive analysis of common copy-number variations in the human genome.

Wong KK, deLeeuw RJ, Dosanjh NS, Kimm LR, Cheng Z, Horsman DE, MacAulay C, Ng RT, Brown CJ, Eichler EE, Lam WL.

Am J Hum Genet. 2007 Jan;80(1):91-104. Epub 2006 Dec 5.


Large fragment Bst DNA polymerase for whole genome amplification of DNA from formalin-fixed paraffin-embedded tissues.

Aviel-Ronen S, Qi Zhu C, Coe BP, Liu N, Watson SK, Lam WL, Tsao MS.

BMC Genomics. 2006 Dec 12;7:312.


Integrated functional visualization of eukaryotic genomes.

Ghai R, Lindemann H, Chakraborty T.

BMC Bioinformatics. 2006 Jul 18;7:348.


A graphical assessment of p-values from sliding window haplotype tests of association to identify asthma susceptibility loci on chromosome 11q.

Mathias RA, Gao P, Goldstein JL, Wilson AF, Pugh EW, Furbert-Harris P, Dunston GM, Malveaux FJ, Togias A, Barnes KC, Beaty TH, Huang SK.

BMC Genet. 2006 Jun 14;7:38.


Differential disruption of cell cycle pathways in small cell and non-small cell lung cancer.

Coe BP, Lockwood WW, Girard L, Chari R, Macaulay C, Lam S, Gazdar AF, Minna JD, Lam WL.

Br J Cancer. 2006 Jun 19;94(12):1927-35. Epub 2006 May 16.


Comprehensive copy number profiles of breast cancer cell model genomes.

Shadeo A, Lam WL.

Breast Cancer Res. 2006;8(1):R9. Epub 2006 Jan 3.

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